The key to how DNA works resides in its
structure and in how it duplicates
In 1957, Matthew Meselson and Franklin Stahl did an
experiment to determine which of the following models
best represented DNA replication:
1.  Did the two strands unwind and each act as a template
for new strands? This is semi-conservative replication,
because each new strand is half comprised of molecules
from the old strand.
2.  Did the strands not unwind, but somehow generate a
new double stranded DNA copy of entirely new
molecules? This is conservative replication.