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the
presence of inhibitors.
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competitive inhibitors are molecules that bind to the
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same
site as the substrate - preventing the substrate
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from
binding as they do so - but are not changed by the
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enzyme.
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noncompetitive inhibitors are molecules that bind to
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some
other site on the enzyme reducing its catalytic
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power.
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pH.
The conformation of a protein is influenced by pH and
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as
enzyme activity is crucially dependent on its
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conformation,
its activity is likewise affected.
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