Importins and exportins
After RNA molecules (mRNA, tRNA and rRNA)
are produced in the nucleus, they must be
exported to the cytoplasm for protein
synthesis.  In addition, proteins operating in the
nucleus must be imported from the
cytoplasm.  The traffic through the nuclear
envelope is mediated by a protein family which
can be divided into exportins and
importins.  Binding of a molecule (a "cargo") to
exportins facilitates its export to the
cytoplasm.  Importins facilitate import into the
nucleus.