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After RNA
molecules (mRNA, tRNA and rRNA)
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are produced in
the nucleus, they must be
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exported to the
cytoplasm for protein
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synthesis.
In addition, proteins operating in the
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nucleus must be
imported from the
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cytoplasm.
The traffic through the nuclear
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envelope is
mediated by a protein family which
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can be divided
into exportins and
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importins.
Binding of a molecule (a "cargo") to
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exportins
facilitates its export to the
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cytoplasm.
Importins facilitate import into the
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nucleus.
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