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| How HIV controls its own mRNA |
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| transport |
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| • | Figure
5-B-2. The role of the |
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| HIV
rev protein. |
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| (a)
The rev protein is a product |
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| of
the doubly spliced |
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| mRNA.
Without rev, export of |
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| unspliced
and singly spliced |
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| mRNAs
(I and II) is very slow. |
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| (b)
The rev protein can bind to |
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| the
rev-response-element |
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| (RRE)
of mRNA I and II, |
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| accelerating
their export. |
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| (c)
Sequences of NLS and |
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| NES
in the rev proten. |
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