Genetic disorders of
collagen are numerous :
One such group of 10
different collagen deficiency
diseases is  the Ehlers-Danlos
(E-D) syndrome.
The “India-rubber man” of
circus fame had an E-D
syndrome.
Osteogenesis imperfecta :
abnormal (fragile) bone
formation in human babies
Paganini may also  have  suffered
from an E-D condition known as
Marfan’s syndrome.