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| Mutagens don’t always start |
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| out
that way |
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| • | Many
compounds that enter out cells are |
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| lipophilic
(typically organic compounds). |
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| These compounds
are not reactive with |
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| DNA. A system of enzymes called P450 |
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| monooxygenases
add oxygen molecules |
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| in order
to make them more soluble but |
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| this
also makes them reactive with DNA. |
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