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XP-E is
thought to be involved with the recognition of
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damaged
DNA because it has the capacity to bind to UV-
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damaged DNA
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XP-F
in association with the ERCC1 protein, incises DNA on
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the 5'
side of the damaged site
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XP-G
incises DNA 3' to the damaged site
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XP-V
protein is a low-fidelity class Y DNA polymerase, that
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can
replicate UV-induced pyrimidine dimers in vivo with the
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insertion
of the correct bases in the daughter strand
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CSA
likely participates in a CSB/RNA polII complex stalled
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at
damaged sites in transcriptionally active DNA that helps
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remove the stalled RNA polII from the DNA damage site.
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CSB is
believed to be a DNA helicase that is required for
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ubiquitinating
RNA polII for its remove and degradation at
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sites
of DNA damage.
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