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| ASSOCIATION WITH HUMAN |
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| CANCERS |
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| 1. Growth
Factor Receptor Increased numbers in 20 percent of breast cancers |
| 2. Ras
Protein Activated by mutations in 20 to 30 percent of cancers |
| 3. Abl
Kinase Activated by abnormal chromosomes in chronic myelogenous
leukemia |
| 4. Src
Kinase Activated by mutations in 2 to 5 percent of cancers |
| 5. p53
Protein Mutated or deleted in 50 percent of cancers |