The First Cholera Outbreak
Asiatic Cholera Pandemic of 1817-23 
Note: This cholera pandemic, occurring during John Snow's early life, did not reach the British isles. 
This was the first great cholera pandemic of the nineteenth century.  It was unprecedented in its fury, affecting almost every country in Asia. While early cases of cholera were reported from Purneah (now Purnia) in Bihar (state in east India) in early 1816, the pandemic is believed to have originated in the town of Jessore (near Calcutta) in August 1817.  A civil surgeon, reporting on the high incidence of a severe gastrointestinal disease among his patients, drew attention to the source of contagion -- contaminated rice.  Amidst attacks of vomiting and diarrhea thousands of people collapsed and died, including hundreds of British soldiers transiting through Bengal.  Cholera then spread rapidly across the country and, in December 1818, arrived in Sri Lanka (Ceylon).