Intersectionality is a concept or perspective that considers the simultaneous manifestation or influence of multiple dimensions of identity, difference, and inequality. The use of intersectionality as an analytical framework in the humanities and social sciences has increased drastically in the past two decades. Much scholarship focused on trans people centralizes the roles of cissexism or transphobia. Given this critical sensitivity to privilege and oppression, scholars engaging in research focused on trans issues may find that several of intersectionality’s core assumptions resonate with their own. Furthermore, adopting an intersectional lens in research with trans people will allow scholars to add nuance and depth to what is already known about manifestations and consequences of cissexism. The purpose of this entry is to serve as a primer for scholars who would like to incorporate intersectionality into research focused on trans people. The entry begins with a brief history of intersectionality, with particular attention devoted to its roots in the thought and praxis of (primarily cisgender [cis]) women of color. Next, the entry describes various approaches to using intersectionality in research. Moreover, examples are offered that illustrate how these approaches may be employed in research on cissexism.