Publications

Peer-reviewed Articles


Hypothalamic control of male aggression-seeking behavior. Falkner AL, Grosenick L, Davidson TJ, Deisseroth K, and D Lin. Nature Neuroscience Advanced Online (2016). Supplementary Information

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior. Ferenczi EA*, Zalocusky KA*, Liston C*, Grosenick L, Warden MR, Amatya D, Katovich K, Mehta H, Patenaude B, Ramakrishnan C, Kalanithi P, Etkin A, Knutson B, Glover GH, and K Deisseroth. Science 351(6268), 2016. *equal contributors Supplementary Materials.

SPED Light Sheet Microscopy: Fast Mapping of Biological System Structure and Function. Tomer R, Lovett-Barron M, Kauvar I, Andalman A, Burns VM, Sankaran S, Grosenick L, Broxton M, Yang S, and K Deisseroth. Cell 163(7):1796–1806 (2015).

Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice. Montgomery KL, Yeh AJ, Ho JS, Tsao V, Iyer SM, Grosenick L, Ferenczi EA, Tanabe Y, Deisseroth K, Delp SL, and ASY Poon. Nature Methods 12 969–974 (2015).

Self-tracking Energy Transfer for Neural Stimulation in Untethered Mice. Ho JS, Tanabe Y, Iyer SM, Christensen AJ, Grosenick L, Deisseroth K, Delp SL, and ASY Poon. Arxiv preprint 2015.

Activity sources from fast large-scale brain recordings in adult Drosophila. Aimon S, Katsuki T, Grosenick L, Broxton M, Deisseroth K, and RJ Greenspan. Biorxiv, 2015.

Closed-loop and activity-guided optogenetic control. L. Grosenick, J. Marshel, and K. Deisseroth. Neuron (2015) 86(1) 106–139.

Enhancing the performance of the light field microscope using wavefront coding. N. Cohen, S. Yang, A. Andalman, M. Broxton, L. Grosenick, S, K. Deisseroth, and M. Levoy. Optics Express (2014) 22(20) 24817–24839.

Natural neural projection dynamics underlying social behavior. L. A. Gunaydin*, L. Grosenick*, J. C. Finkelstein*, I. V. Kauvar*, L. E. Fenno, A. Adhikari, S. Lammel, J. J. Mirzabekov, R. D. Airan, K. A. Zalocusky, K. M. Tye, P. Anikeeva, R. C. Malenka, and K. Deisseroth. Cell (2014) 157, 1535-1551. *equal contributors

Targeting cells with single vectors using multiple-feature Boolean logic. L. E. Fenno, J. Mattis, C. Ramakrishnan, M. Hyun, S. Y. Lee, M. He, J. Tucciarone, A. Selimbeyoglu, A. Berndt, L. Grosenick, K. A. Zalocusky, H. Bernstein, H. Swanson, C. Perry, I. Diester, F. M. Boyce, C. E. Bass, R. Neve, Z. J. Huang, and K. Deisseroth. Nature Methods (2014). Supplementary Information.

Wave Optics Theory and 3-D Deconvolution for the Light Field Microscope. M. Broxton, L. Grosenick, S. Yang, N. Cohen, A. Andalman, K. Deisseroth, and M. Levoy. Optics Express (2013) 21(21) 25418–25439.

Intepretable Whole-Brain Prediction Analysis with GraphNet. L. Grosenick, B. Klingenberg, Kiefer Katovich, B. Knutson, J. E. Taylor. NeuroImage (2013) 72(15):304–321.

A Generalized Least Squares Matrix Decomposition. G. I. Allen, L. Grosenick, J. E. Taylor. J American Statistical Association (2013).

The Open Connectome Project Data Cluster: Scalable Analysis and Vision for High-Throughput Neuroscience. R. Burns, W. Gray Roncal, D. Kleissas, K. Lillaney, P. Manavalan, E. Perlman, D. R. Berger, D. D. Bock, K. Chung, L. Grosenick, N. Kasthuri, N. C. Weiler, K. Deisseroth, M. Kazhdan, J. Lichtman, R. C. Reid, S. J. Smith, A. S. Szalay, J. T. Vogelstein, R. J. Vogelstein. Proceedings of the 25th International Conference on Scientific and Statistical Database Management (SSDBM) (2013) Article No. 27.


 

Structural and molecular interrogation of intact biological systems.

K. Chung, J. Wallace, S.-Y. Kim, S. Kalyanasundaram, A. S. Andalman, T. J. Davidson, J. J. Mirzabekov, K. A. Zalocusky, J. Mattis, A. K. Denisin, S. Pak, H. Bernstein, C. Ramakrishnan, L. Grosenick, V. Gradinaru, and K. Deisseroth.

Nature (2013) 497:332–337 (cover).

See CLARITY web page for supplementary movies and information, and check out the Chung Lab at MIT.


Deterministic matrices matching the compressed sensing phase transitions of Gaussian random matrices. H. Monajemi, S. Jafarpour, M. Gavish, Stat 330/CME 362 Collaboration*, and D. L. Donoho PNAS (2012). * Stat 330/CME 362 Collaboration is S. Ambikasaran, S. Bacallado, D. Bharadia, Y. Chen, Y. Choi, M. Chowdhury, S. Chowdhury, A. Damle, W. Fithian, G. Goetz, L. Grosenick, S. Gross, G. Hills, M. Hornstein, M. Lakkam, J. Lee, J. Li, L. Liu, C. Sing-Long, M. Marx, A. Mittal, H. Monajemi, A. No, R. Omrani, L. Pekelis, J. Qin, K. S. Raines, E. Ryu, A. Saxe, D. Shi, K. Siilats, D. Strauss, G. Tang, C. Wang, Z. Zhou, and Z. Zhu.

Optetrode: a multichannel readout for optogenetic control in freely moving mice. P. Anikeeva, A. S. Andalman, I. Witten, M. Warden, I. Goshen, L. Grosenick, L. Gunaydin, L. M. Frank, and K. Deisseroth. Nature Neuroscience (2011) 15, 163–170.

Amygdala circuitry mediating reversible and bidirectional control of anxiety. K. M. Tye*, R. Prakash*, S.-Y. Kim*, L. E. Fenno*, L. Grosenick, H. Zarabi, K. R. Thompson, V. Gradinaru, C. Ramakrishnan, and K. Deisseroth. Nature (2011) 471, 358–362. *equal contributors.

Elastic Source Selection for in vivo imaging of neuronal ensembles. L. Grosenick, and T. Anderson and Stephen J. Smith. From Nano to Macro, 6th IEEE International Symposium on Biomedical Imaging. (2009) 1263–1266.

EEG classification by ICA source selection of Laplacian-filtered data. C. G. Carvalhaes, M. Perreau Guimaraes, L. Grosenick and P. Suppes. From Nano to Macro, 6th IEEE International Symposium on Biomedical Imaging. (2009) 1003–1006.

Interpretable classifiers for fMRI improve prediction of purchases. L. Grosenick, S. M. Greer, and B. Knutson. IEEE transactions on Neural Systems and Rehabilitation Engineering (2008) 16(6):539–549.


 

Fish can infer social rank by observation alone.

L. Grosenick, T. S. Clement, and R. D. Fernald.

Nature (2007) 445:429-432 (cover).
supplement


Quantifying inter-subject agreement in brain-imaging analyses. D. K. Wong*, L. Grosenick*, T. Uy, M. Perreau Guimaraes, C. G. Carvalhaes, P. Desain, and P. Suppes. NeuroImage (2007) 39(3):1051–1063/. *equal contributors.

Single-trial classification of MEG recordings. M. Perreau Guimaraes, D. K. Wong, T. Uy, L. Grosenick, and P. Suppes. IEEE transactions on Biomedical Engineering (2007) 54(3):436–443.

Expression, structure, function, and evolution of gonadotropin-releasing hormone (GnRH) receptors GnRH-R1SHS and GnRH-R2PEY in the teleost, Astatotilapia burtoni. C. A. Flanagan, C.-C. Chen, M. Coetsee, S. Mamputha, K. E. Whitlock, N. Bredenkamp, L. Grosenick, R. D. Fernald, and N. Illing. Endocrinology (2007) 148(10):5060–5071.

Multichannel classification of single EEG trials with Independent Component Analysis. D. K. Wong, M. Perreau Guimaraes, T. Uy, L. Grosenick, and P. Suppes. Advances in Neural Networks-ISNN 2006 541–547.

Invited Talks


Identification of cellular-activity timing relationships spanning large tissue volumes during behavior. L. Grosenick*, M. Broxton*, C. K. Kim*, C. Liston*, P. Kalanithi, B. Poole, S. Yang, A. Andalman, T. Anderson, Louis C. Leung, E. Scharff, E. Ferenczi, J. Vogelstein, N. Cohen, A. Levskaya, Z. Zhang, O. Yizhar, R. Madelaine, C. Ramakrishnan, S. Ganguli, A. Muto, K. Kawakami, P. Mourrain, S. J. Smith, P. Suppes, M. Levoy, and K. Deisseroth. FENS Spring Brain Conference 2014: Controlling Neurons, Circuits, and Behavior. *equal contributors

Synchronous 3D imaging of large neural populations with single-neuron resolution at video rates in vitro and in vivo with light field microscopy. L. Grosenick*, M. Broxton*, C. K. Kim*, C. Liston*, S. Yang, A. Andalman, N. Cohen, L. Leung, B. Poole, J. Vogelstein, T. Anderson, Z. Zhang, O. Yizhar, B. Grone, C. Ramakrishnan, A. Muto, K. Kawakami, P. Mourrain, S. J. Smith, P. Suppes, M. Levoy, K. Deisseroth. (2013) Olympus Fourth Annual Neuroimaging Symposium: Functional brain imaging with cellular resolution (at Society for Neuroscience 2013). *equal contributors

Cosyne Workshops 2011 Towards closed-loop system identification and control of neural circuits with optogenetics. L. Grosenick, J. Mattis, M. Broxton, O. Yizhar, M. Levoy, and K. Deisseroth.

Fast, interpretable multivariate methods for whole-brain fMRI. Organization of Human Brain Mapping. 2010. Trainee Abstract Award. L. Grosenick, B.Klingenberg, B. Knutson, J.E. Taylor.

Fast classification, regression, and multivariate methods for sparse but structured data with applications to whole-brain fMRI and volumetric calcium imaging. Columbia Department of Statistics. 2010. L. Grosenick, B.Klingenberg, B. Knutson, G. I. Allen, J.E. Taylor.

Fast, interpretable multivariate models for whole-brain fMRI regression and classification. Johns Hopkins University Whiting School of Engineering. 2010. L. Grosenick, B.Klingenberg, B. Knutson, J.E. Taylor.

Elastic Source Selection for In Vivo Imaging of Neuronal Ensembles. IEEE International Symposium on Biomedical Imaging. 2009. L. Grosenick, T. Anderson, S. J. Smith.

Selected Conference Posters


Synchronous 3-D imaging of large neural populations with single-neuron resolution at video rates in vitro and in vivo with light field microscopy. L. Grosenick*, M. Broxton*, C. K. Kim*, C. Liston*, S. Yang, A. Andalman, N. Cohen, L. Leung, B. Poole, J. Vogelstein, T. Anderson, Z. Zhang, O. Yizhar, B. Grone, C. Ramakrishnan, A. Muto, K. Kawakami, P. Mourrain, S. J. Smith, P. Suppes, M. Levoy, K. Deisseroth. (2013) Society for Neuroscience (SfN). *equal contributors

Real-time optical measurement of projection activity: dynamics of genetically- and anatomically-defined neuronal afferents predict social behavior in freely moving mice. L. A. Gunaydin*, I. V. Kauvar*, L. Grosenick*, and K. Deisseroth. (2013) Society for Neuroscience (SfN). *equal contributors

Whole-Brain Spatio-Temporal Dimension Reduction via Sparse Generalized PCA. G. I. Allen, L. Grosenick, J. E. Taylor. Organization of Human Brain Mapping (OHBM) 2011.

Whole-brain Sparse Penalized Discriminant Analysis for Predicting Choice. L. Grosenick, B. Klingenberg, S. Greer, J. E. Taylor, and B. Knutson. Organization of Human Brain Mapping (OHBM) 2009.

Single-Trial Classification and Representation of Melody in the Brain. L. Grosenick, D. B. Franzson, L. Harbott, M. Perreau-Guimaeres, B. Bohannan, and P. Suppes. Association for Psychological Science.