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At last (*whoopee*) the Proceedings of Symposium hosted by Charles
Boyd and me last March has been published by the New York Academy of
Sciences (volume 800). There are so many excellent papers in this
book that I wouldn't presume to pick a limited number for special
comment. Accordingly, for November, I am posting the Table of
Contents.
Volume 800
November 18, 1996
THE ABDOMINAL AORTIC ANEURYSM:
GENETICS, PATHOPHYSIOLOGY, AND
MOLECULAR BIOLOGY
Editors and Conference Organizers
M. David Tilson and Charles D. Boyd
CONTENTS
Introductory Remarks. By M. David Tilson.
Part I. Epidemiology of the Abdominal Aortic
Aneurysm, Clinical Genetics, and Screening
Incidence and Prevalence of Abdominal Aortic Aneurysms,
Estimated by Necropsy Studies and Population Screening by
Ultrasound. By Henrik Bengtsson, Bj^Ôrn Sonesson, and
David Bergqvist. . . . .
Relationship of Cardiovascular Risk Factors to Racial
Differences in Femoral Bypass Surgery and Abdominal
Aortic Aneurysmectomy in Massachusetts. By Wayne W.
LaMorte, Thayer E. Scott, and James O. Menzoian. . . .
The Oxford Screening Program for Aortic Aneurysm and
Screening First-Order Male Siblings of Probands with
Abdominal Aortic Aneurysm. By Jack Collin. . .
.
Genetic Aspects of Abdominal Aortic Aneurysm. By Alain
Verloes, Natzi Sakalihasan, Raymond Limet, and Lucien
Koulischer. . . .
Variables That Affect the Expansion Rate and Rupture of
Abdominal Aortic Aneurysms. By Jack L. Cronenwett. . .
.
Incidence of Cancer and Abdominal Aortic Aneurysms. A
Logistic Regression Analysis. By Emily L. Chan, Paula
Belem, Rocco G. Ciocca, Derald Madsen, Ronald P. Cody,
James W. Mackenzie, Charles D. Boyd, and Alan M. Graham.
.
Part II. Pathophysiology and Animal Models
Inflammatory Aspects of Experimental Aneurysms. Effect
of Methylprednisolone and Cyclosporine. By Philip B.
Dobrin, Norbert Baumgartner, Samy Anidjar, Gregorio
Chejfec, and Robert Mrkvicka. . . .
Effects of Hypertension and Propranolol upon Aneurysm
Expansion in the Andijar/Dobrin Aneurysm Model. By
Michael A. Ricci, Jeffrey M. Slaiby, Gregory R. Gadowski,
Edith D. Hendley, Patricia Nichols, and David B. Pilcher.
. . .
Formation and Growth of Aortic Aneurysms Induced by
Adventitial Elastolysis. By John V. White and Stacey L.
Mazzacco. . .
Hemodynamic and Biochemical Characteristics of the Aorta
in the WKY, SHR, WKHT, and WKHA Rat Strains. By Michael
A. Ricci, Jeffrey M. Slaiby, Edith D. Hendley, William
Stirewalt, Lise Cloutier, Patricia Nichols, and John N.
Evans. . . .
Part III. Enzymology of Matrix Destruction
Role of Serine Proteases in Aneurysm Development. By
Srinivasa K. Rao, Krishna V. Reddy, and Jon R. Cohen. .
.
Biochemistry and Molecular Regulation of Matrix
Macromolecules in Abdominal Aortic Aneurysms. By Anuja
Ghorpade and B. Timothy Baxter. . . .
Plasminogen Activators in Abdominal Aortic Aneurysmal
Disease. By Jeffrey M. Reilly. .
Role of Matrix Metalloproteinases in Abdominal Aortic
Aneurysms. By Robert W. Thompson and William C. Parks.
. .
Cellular Components and Features of Immune Response in
Abdominal Aortic Aneurysms. By William H. Pearce and
Alisa E. Koch. . .
Part IV. Molecular Approaches to the Etiology and
Aneurysms
Candidate Genes for Abdominal Aortic Aneurysms. By
Helena Kuvaniemi, Sandra J. Watton, Simon J. Price,
Yinying Zhu, Zoran Gatalica, and Gerard Tromp. .
.
Interaction between Fibrillin Genotype and Blood Pressure
and the Development of Aneurysmal Disease. By J. T.
Powell, S. T. R. MacSweeney, R. M. Greenhalgh, R. J.
Turner, and A. M. Henney. . .
A Genetic Basis for Autoimmune Manifestations in the
Abdominal Aortic Aneurysm Resides in the MHC Class II
Locus DR-beta-l. By M. David Tilson, Kathleen J.
Ozsvath, Hitoshi Hirose, and Shichao Xia. . . .
Multiple Defects in Type III Collagen Synthesis Are
Associated with the Pathogenesis of Abdominal Aortic
Aneurysms. By David W. Anderson, Troy K. Edwards,
Michael H. Ricketts, Helena Kuivaniemi, Gerard C. Tromp,
Catherine A. Stolle, Susan B. Deak, and Charles D. Boyd.
. .
Closing Remarks and Conference Summary. By Charles
D. Boyd and M. David Tilson
Poster Papers
A Modern Series of Ruptured Intrarenal Aortic Aneurysms.
Improved Survival at a Cost. By Enrico Ascer, Patrick S.
DePippo, Judith Hanson, William Yorkovich, and Elke
Lorenson. . .
Predicting Survival from Ruptured Abdominal Aortic
Aneurysm. Computer Modeling with AIMTM versus Clinical
Judgment. By Lise Cloutier, Michael A. Ricci, Steven
Wald, Jens Eldrup-Jorgensen,and Carl Bredenberg. . .
Detection of Chlamydia pneumoniae in Abdominal Aortic
Aneurysms. By Jukka Juvonen, Tatu Juvonen, Aino Laurila,
Hannu Alak, Kari Lounatmaa, Marja Surcel, Maija Leinonen,
Matti I. Kairaluoma, and Pekka Saikku. . .
Trace Elements, Atherosclerosis, and Abdominal Aneurysms.
By Leslie M. Klevay. . .
Identification of Uric Acid in Aortic Aneurysms and
Atherosclerotic Artery. By Peter Patetsios, Wiliam
Rodino, Willem Wisselink, Douglas Bryan, John D. Kirwin,
and Thomas F. Panetta. . .
Smoking as a Risk Factor for Abdominal Aortic Aneurysm.
By J. T. Powell, P. Worrell, S. T. R. MacSweeney, P. J.
Franks, and R. M. Greenhalgh. . .
The UK Small Aneurysm Trial. By J. T. Powell, R. M.
Greenhalgh, C. V. Ruckley, and F. G. R. Fowkes. . .
Design of a Trial to Evaluate the Effect of Propranolol
upon Abdominal Aortic Aneurysm Expansion. By Michael
A. Ricci, David B. Pilcher, and Ruth McBride. . .
Abdominal Aortic Aneurysm with Left Iliac Aneurysm in
Identical Twins. By Michael A. Ricci, Beth Nutter,
Iris McDonald, and Gail Strindberg. . .
Aortic Aneurysmal Disease in Women. Is There a Greater
Incidence of Suprarenal Involvement? By Michael F.
Silane, Kathleen M. Conte, Gary A. Fantini, and Elias
Kazam. . .
Replicas of Human Aortic and Iliac Artery Aneurysms for
Endovascular Repair. Practice Makes Perfect. By W.
Wisselink, W. Rodino, P. Patetsios, J. D. Kirwin, D. H.
Bryan, and T. F. Panetta. . .
Elastin Degradation Products Induce Adventitial
Angiogenesis in the Anidjar/Dobrin Rat Aneurysm Model.
By Gary B. Nackman, Fredrick J. Karkowski, Vivian J.
Halpern, Harold P. Gaetz, and M. David Tilson. . .
Suppression of Experimental Aneurysmal Degeneration with
Chemically Modified Tetracycline Derivatives. By Drazen
Petrinec, Dennis R. Holmes, Shiziong Liao, Lorne M.
Golub, and Robert W. Thompson. .
CD-18 Monoclonal Antibody Blocks the Early Events of
Aneurysm Expansion. By G. Strindberg, M. A. Ricci,
R. S. Guibord, M. Mercier, P. Nichols, and M. M. Bednar.
. .
Do Aneurysms Cause Atherosclerosis? By Bauer Sumpio and
M. David Tilson. . .
An in Vitro Model of Aneurysmal Disease: Effect of
Leukocyte Infiltration and Shear Stress on MMP Production
within the Arterial Wall. By M. M. Thompson, A. Wills,
E. McDermott, M. Crowther, N. Brindle, and P. R. F. Bell.
. .
Wall Strength and Stiffness of Aneurysmal and
Nonaneurysmal Abdominal Aorta. By David A. Vorp, M. L.
Raghavan, Satish C. Muluk, Michel S. Makaroun, David L.
Steed, Ron Shapiro, and Marshall W. Webster. . .
Neovascularization in the Abdominal Aortic Aneurysm.
Endothelial Nitric Oxide Synthase, Nitric Oxide, and
Elastolysis. By David Paik and M. David Tilson. . .
Decrease of Plasma Vitamin E ( -Tocopherol) Levels in
Patients with Abdominal Aortic Aneurysm. By N.
Sakalihasan, J. Pincemail, J. O. Defraigne, B. Nusgens,
C. Lapiere, and R. Limet. . .
Aneurysmal Smooth Muscle Cells Exhibit Increased Matrix
Metalloproteinase-2 Production in Vitro. By M. Crowther,
N. P. J. Brindle, R. Sayers, P. R. F. Bell, and M. M.
Thompson. . .
Smooth Muscle Cell Apoptosis and p53 Expression in Human
Abdominal Aortic Aneurysms. By Dennis R. Holmes, Angel
L¢pez-Candales, Shixiong Liao, and Robert W. Thompson.
. .
Molecular Mimicry in Human Aortic Aneurysmal Diseases.
By K. J. Ozsvath, H. Hirose, S. Xia, and M. D. Tilson.
. .
Phenotypic Overlap between Familial Aneurysms and
Ehlers-Danlos Type IV Resulting from a Type III
Procollagen Gene Mutation. By David W. Anderson, Smita
Thakker-Varia, and Catherine A. Stolle. .