Dr. Santella's Lab


Our research involves the development of laboratory methods for the detection of human exposure to environmental and occupational carcinogens and their use in molecular epidemiology studies to identify causative factors, susceptible populations, and preventive interventions. Work has concentrated on the measurement of carcinogens bound to DNA or protein using highly specific and sensitive immunoassays (ELISA and immunohistochemistry). The relationship between polymorphisms in genes involved in the activation and detoxification of chemical carcinogens as well as repair of DNA adducts are being investigated to better understand individual differences in risk for cancer development.
Regina M. Santella, Ph.D.
rps1@columbia.edu
Mailman School of Public Health
Department of Environmental Health Sciences
630 West 168th Street
New York, NY 10032
Telephone:(212) 305-1996
Fax: (212) 305-5328


Information On Monoclonal Antibodies
Information On Immunoassay Methods
Immunohistochemistry Pictures
List of publications: 1995 to present
Meet The Lab

 

Related Sites

Columbia University Homepage

Mailman School of Public Health

Department of Environmental Health Sciences

NIEHS Center for Environmental Health in Northern Manhattan

Herbert Irving Comprehensive Cancer Center

Biomarkers Core Facility

American Association of Cancer Research

Women in Cancer Research

Molecular Epidemiology Group (MEG/AACR)