Pituitary

• Adenoma: (MEN 1, McCune-Albright)

• Non-functioning Macroadenoma 15-25%

• Prolactin 40-60%

• GH 20%

• Prl + GH 9%

• ACTH 3%

• FSH/LH 2%

• TSH Rare

• Tumors

• Infiltrative: Langerhans Cell (Hand-Schuller-Christian, Eosinophilic), Sarcoid, Hemochromatosis ( HFE C282Y, H63D)

• Autoimmune: Lymphocytic Hypophysitis

• Infectious: Abscess, TB, Mycoses

• Vascular: Aneurysm, Hemorrhage (Sheehans)

• Trauma: Surgery, Irradiation, Chemotherapy

• Empty Sella Syndrome