Adrenal

• Adrenal Cushing Syndrome:

• Adenoma

• Carcinoma

• Bilateral Micronodular Hyperplasia: Carney’s syndrome (lentigines, atrial myxomas, adrenla hyperplasia ¼ of patinets) PRKAR1A

• Bilateral Macronodular Hyperplasia: McCune-Albright, GIP receptor

• CAH:

• 21-hydroxylase deficincy: Increased 17-0HP, Decreased E2, Decreased Mineralcorticoid

• 11-β-hydroxylase deficiency: Increased DOC/11-Deoxycortisol Decreased E2, Increased mineralcorticoid activity

• 17-α-hydroxylase deficiency: Increased DOC/Corticosterone, Decreased Androgens and E2

• 3- β-hydroxysteroid dehydrogenase deficiency deficiency: Increased DHEAS, Decreased E2