Alkaline Phosphatase

• Encoded by 3 Genes with Multiple Isoenzymes:

• 1)Tissue Unspecific: Liver, Bone, 1st Trimester Pregnancy, Kidney

• 2) Intestine, 3rd Trimester Pregnancy

• 3) Intestine

• Post-prandial Increase: Blood Group O and B Secretors

• Regan Isoenzyme (Carcinoplacental): Tumor Marker

• (Lung, Gasrtic, Ovarian, Renal, Osteosarcoma, Uterine, Hodgkin)