Osteomalacic Disorders

• Vitamin D Deficiency:

• Lack of sun exposure

• Primary nutritional

• Gastrtectomy

• Malabsorption syndromes

• Activation/Catabolism:

• Liver Disease

• Vitamin D dependent Rickets I

• Anticonvulsants

• Steroids

• Vitamin D Resistance:

• Inherited Vitamin D dependent Rickets II (HVDRR)

• Oncogenic

• Calcium Deficiency:

• Calcium –deficient nutrition/malabsorption

• High Dietary phytate

• Phosphate Depletion:

• Renal Phopshate Leak

• Phophate-binding Antacids

• Osteoblastic Skeletal Metastates

• Renal Disease:

• RTA

• Renal Osteodystrophy

• Aluminum

• Hypophosphatasia

• Medications:

• Etidronate

• Fluoride