Drugs Associated With Gynecomastia

• Estrogens or Estrogen-Like Agents:

• DES, OCP, Estrogen-containing cosmetics, Phytoestrogens (bourbon), Marijuana, Digitalis

• Drugs that Enhance Estrogen Production:

• Anabolic Steroids, Gonadotropins, Clomiphene

• Drugs that Inhibit Testosterone Synthysis/Action:

• Ketoconazole, Metronidazole, Finansteride, Cimetidine, Alkylating Agents, Flutimide, Spironolactone, Alcohol

• Multiple/Unknown Mechanism: INH, Calcium Channel Blockers, Captopril, TCA, Opiates, Phenytoin