Biology C2005/F2401 - 2003
Schedule of Lectures, Recommended Readings & Exams, 2003
Students with older editions of the texts can consult older reading lists and find the readings for the same topics:
2002, 2001 (Becker 4th ed.) , 2000 (Purves 5th ed.) , 1999, 1998

Prof. Purves welcomes comments on his text; e-mail him at [email protected]
Last modified: 08/30/04 10:10 AM

Lecture:
(C)hasin
(M)owsh.
 Date  Subject of Lecture Recommended reading in Becker 5th ed.(B) or Purves 6th ed. (P)
1 (C) Tu
9/2/03
Introduction. Living things. Cells. Exponential growth. B: Ch.1; Ch.2 p.17-31
P: Ch.1; Ch. 4 p.55-62
2 (C) Th
9/4/03
Water. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. Polysaccharides. Lipids. Amino acids. Stereo-isomers B: Ch.3 p.41-44, 60-71
P: Ch.2
P:Ch.3 p.34-35, 43-46, 49-53
3 (C) Tu
9/9/03
Protein structure. Peptide bonds. Alpha helix. Beta sheet. 3-D structure. Subunit interaction. B: Ch.3 p.44-54
 
+ Ch.2 p.31-37
P: Ch.3 p.
36-42
4 (C) Th
9/11/03
Membrane proteins. Catalysis. Enzymes. Protein purification methods. B: Ch.7 p.175-184
P: Ch.5 p.79-82;
     Ch.6 p.102-105
5 (C) Tu
9/16/03
Enzyme kinetics. Enzyme inhibitors. Feedback inhibition. B: Ch.6 
P: Ch.6 p.105-112
6 (C) Th
9/18/03
Transfer of energy. ATP. Free energy. Introduction to energy metabolism. B: Ch.5; Ch.13 p.368-372
P: Ch.6 p. 95-102
7(C) Tu
9/23/03
Glycolysis as a pathway in intermediary metabolism.  Anaerobiosis. B: Ch.13 p.372-386
P: Ch.7 p.113-121 
Exam#1 Th 9/25/03 Covers topics actually covered in lectures 1 - 6 inclusive. Note exams are not at morning class times. 
Optional review session (questions answered) at morning class time in 700 Fairchild.
5:40 - 6:55 PM and
7:30 - 8:45PM *
Room(s) TBA
8 (C) Tu 
9/30/03
Krebs (TCA) cycle. Electron transport. Oxidative phosphorylation. B: Ch. 14
P: Ch.7 p.122-130
9 (C) Th   
10/2/03
Alternative energy sources. Biosynthetic pathways.  Regulation of pathways.  B: Ch.6 p.147-151; Ch.13 p.386-392
P: Ch.7: p.130-134
10 (M) Tu
10/7/03
last day to drop
DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication B: Ch 3 p.54-60 (+Box3A) 
  + Ch 16 p. 479-491

P: Ch 3 p. 47-49; 
Ch 11:198-205 +Fig.14.7
11(M) Th
10/9/03
Details of DNA synthesis and PCR B: Ch 17 p. 525-538
P: Ch 11 p. 206-end.
12(M) Tu
10/14/03
Transcription & the central dogma B: Ch 19 p. 623-640
  + p. 654-end

P: Ch 12 to p. 223 
13(M) Th
10/16/03
Translation and the genetic code. B:Ch 20 p. 660-674
P: Ch 12 p. 223-231
14(M) Tu
10/21/03
Wrap up of translation; Mutation 

Regulation of protein synthesis in eukaryotes.

B: Ch 20 p. 674-676
P: Ch 12 p. 233 - end
B: Ch 21 p. 692-701

P: Ch 13 p. 249-end
Exam #2 Thu
10/23/03
Exam #2. Covers topics of lectures 7 -  12: Free energy through transcription & the central dogma. Optional review session (questions answered) at morning class time. 5:40 - 6:55PM and
7:30 - 8:45PM *
Room(s) TBA
15(M) Tu  
10/28/03
Bacterial and viral reproduction. B: Ch 18 p.598-603 + Box 16A (p. 484-485)
P: Ch 13 to p. 249 
16(M) Th
10/30/03
Restriction enzymes & recombinant DNA technology I. Gene cloning & forensics.  B: Ch. 18: p. 606-end;
B: Ch. 16: 492--496 & Box 16-C. 
P: Ch. 1
7
-- Tu 11/4/03T Election day - no class  
17(M) Th 11/6/03 Recombinant DNA tech. II. Blots and probes. Discoveries about Eukaryotic gene/genome structure. Introns and exons. Same as above. Also
B: Ch. 19 p.647-653

P: Ch. 14 p. 265-270
 
       
18(M) Tu
11/11/03
Eukaryotic cell division I: Mitosis and the cell cycle (will do details of cell cycle and chromosome structure next term); meiosis B: Ch. 17 p. 523-525 & 544-554
P: Ch. 9 p. 155-167
19(M) Th
11/13/03
Eukaryotic cell division II: Consequences of Meiosis -- sex determination, non- disjunction, life cycles & intro to genetics B: Ch 18 p. 577-590.
P: Ch 9 p. 167-end
20(M) Tu  11/18/03 Eukaryotic genetics I: One gene at a time. B: Ch 18 p. 590-595
P: Ch 10 p.
176-188, 192-196 (skip dihybrid crosses for now)
Exam #3  Th  11/20/03 Exam #3: Covers topics of lectures 13-19.  Optional review session (questions answered) at morning class time. 5:40 - 6:55PM and
7:30 - 8:45PM *
Room(s) TBA
21(M) Tu
11/25/03
Eukaryotic genetics II: Genetic diseases, crosses with more than one gene at a time. Crossing over, linkage and mapping B: Ch 18 p 595-598
P: Ch 10 p 188-193 
+ Ch 18 p 331-342, 346-end
-- Th 11/27/03 Thanksgiving - no class  
22(M) Tu
12/2/03
Wrap up of crossing over, linkage and mapping

Intro to Darwinian evolution & population genetics
same as lec. 21

P: Ch.21

23(M) Th   12/4/03 Population genetics and molecular evolution  (last lecture) P: Ch. 24
Rev session
(M)
Th 12/11 or Tu 12/16/03 Review session (optional) Times & Rooms TBA 
  Th 
12/18/03
4:10 - 7 P.M.
Exam #4.   EMPHASIZES LECTURES 20 - 23, but can refer back to entire course.
4:10-7 PM. Note that this is NOT the standard final exam time for a TTh 10:35 class; make your travel arrangements accordingly.
 
    * For students with a class conflict at 5:40 AND 7:30, should  contact Dr. Chasin to search for an alternative.