Biology C2005/F2401 - 2005 -- Revised 11/16/05
Re-Revised Schedule of Lectures, Recommended Readings & Exams, 2005 Updated 12/01/2005 05:15 PM
Students with older editions of the texts can consult older reading lists and find the readings for the same topics:
(
2004, (Purves 7th ed; Becker 5th), 2003 (Purves 6th ed; Becker 5th) , 2002, 2001 (Purves 6th ed; Becker 4th ed.) , 2000 (Purves 5th ed, Becker 4th.)
Prof. Purves welcomes comments on his text; e-mail him at [email protected]

Lecture
(+link):
(C)hasin
(M)owsh.
 Date  Subject of Lecture Recommended reading in Becker 6th ed. (B) or Purves 7th ed. (P)
1 (C) Tu
9/6/05
Introduction. Living things. Cells. Exponential growth. B: CH.1; Ch.2:16-19,20-23; Ch.4:74-79
P: Ch.1 + Ch.4: p.62-70
2 (C) Th
9/8/05
Water. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. Polysaccharides. Lipids. Amino acids. Stereo-isomers B: 61-70
P: Ch.2
P: CH.3 p.35-38, 45-54, 57-58
3 (C) Tu
9/13/05
Protein structure. Peptide bonds. Alpha helix. Beta sheet. 3-D structure. Subunit interaction. B:Ch2: 25-37; Ch.3: 40-53
P: Ch.3 38-45
4 (C) Th
9/15/05
Membrane proteins. Catalysis. Enzymes. Protein purification methods. B: Ch.2:23-25; Ch.6:129-136; Ch.7:173-176
P: Ch.5 87-91
  Ch.6 113-115
5 (C) Tu
9/20/05
Enzyme kinetics. Enzyme inhibitors. Feedback inhibition. B: rest of Ch.6
P: Ch.6 115-123
6 (C) Th
9/22/05
Transfer of energy. ATP. Free energy. Introduction to energy metabolism. B: Ch. 5; Ch. 9: 221-225
P: Ch.6 106-113
7(C) Tu
9/27/05
Glycolysis as a pathway in intermediary metabolism.  Anaerobiosis. B: CH.9: 226-234
P: Ch.7 125-131
Exam#1 Th
9/29/05
Exam #1. Covers topics actually covered in lectures 1 - 6 inclusive. Note exams are not at morning class times. 
Optional review session (questions answered) at morning class time and place.
5:40 - 7:20 PM and
7:30 - 9:10M *
Room(s) TBA
8 (C) Tu 
10/4/05
Krebs (TCA) cycle. Electron transport. Oxidative phosphorylation. ** B: Ch.10
P: Ch.7 131-140
9 (M) Th
10/6/05
DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication B: Ch 3: 53-60 & Box 3A; Ch 18:510-523
P: Ch 3 p. 54-end
Ch. 11 to p 220 & fig. 14.5
10 (M) Tu   
10/11/05
Details of DNA synthesis and PCR B: Ch. 19 556-569
P: Ch 11 p. 220-end
  Th
10/13/05
NO CLASS (A lecture will be held on the first study day to make up for the missed class)  
11(C) Tu
10/18/05
Metabolism reprised: Alternative energy sources. Biosynthetic pathways.  Regulation of pathways. ** B: Ch.: 234-238; optional glance:Ch.11
P: Ch.7 140-143
12(M) Th
10/20/05
Transcription & the central dogma B: Ch 21: 649-665 & 680-end.
P: Ch 12 to p.
239
  Tu
10/25/05
NO CLASS; a makeup lecture will be given on a Friday am. and Monday pm (exact time and place TBA)  
Exam #2 Thu
10/27/05
Exam #2. Covers topics of lectures 7 - 12. Optional review session (questions answered) at morning class time and place. 5:40 - 7:20 PM and
7:30 - 9:10PM *
Room(s) TBA
    The make up classes scheduled for 10/28 & 10/31 have been postponed. The make up lectures will be on Fri. 11/11 at 10:35 AM and Mon. 11/14 at 7 PM. (Same lecture both times.) See below for rooms.  
13(M) Tu
11/1/05
Translation and the genetic code. B: Ch 22 to p. 698
P: Ch 12 p. 239-247
14(M) Th 
11/3/05
Wrap up of translation; Mutation 
 
Regulation of protein synthesis in prokaryotes.
B: Ch 22: 698-700
P: Ch 12 p. 250-end
B: Ch 23 to p. 723.

P: Ch 13 p. 269-end
  Tu
11/8/05
ELECTION DAY - NO CLASS  
15(M) Th
11/10/05
Bacterial and viral reproduction. B: Ch 20: 625-631 & Box 18A (p.515-517)
P: Ch 13 to p. 269
16(M)
16 audio WAV
Fri 10:35 AM
11/11/05
301 Pupin
Restriction enzymes & recombinant DNA technology I.
Gene cloning & forensics.  Note lecture is in 301 Pupin. We couldn't get the usual room.
B: Ch 18: 524-527 & Box 18C (534-535)
B: Ch 20: 633-end.
P: Ch 16
  Mon 7PM
11/14/05
417 IAB
(Repeat of previous Fri.) Note lecture is at 7 PM in 417 IAB. We couldn't get the usual room at the usual time. Same as above
17(M) Tu
11/15/05
Recombinant DNA tech. II. Blots and probes. Discoveries about Eukaryotic gene/genome structure. Introns and exons. Same as previous lecture. Also
B: Ch 21: 673-679.

P: Ch 14 p. 285-290
18(M) Th
11/17/05
We are one lecture behind. See above for material to be covered on 11/17; see outline for details. We will try to catch up somewhat in later lectures.  
19(M) Tu
11/22/05
Eukaryotic cell division I: Mitosis and the cell cycle (will do details of cell cycle and chromosome structure next term); intro to meiosis B: Ch 19: 554-556 & 576-586.
P: Ch 9 to p. 177
-- Th 11/24/05 Thanksgiving - no class  
20(M) Tu  11/29/05 Eukaryotic cell division II & Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and simple inheritance. B: Ch 20: to p 617.
P: Ch 9 p. 177-end
Exam #3  Th
12/1/05
Exam #3: Covers topics of lectures 13 - 19.  Optional review session (questions answered) at morning class time and place. 5:40 - 7:20PM and
7:30 - 9:10M *
Room(s) TBA
21(M) Tu 12/6/05 Eukaryotic genetics I: One gene at a time. B: Ch 20: 617-621
P: Ch 10 to p. 200, 205-end (skip dihybrid crosses for now)
22(M)
22audio
WAV
Th
12/8/05
Eukaryotic genetics II: Genetic diseases, crosses with more than one gene at a time. Crossing over, linkage and mapping B: Ch 20: 622-625
P: Ch 10 -- the rest, Ch 17 to p. 350 & 355-end. (cancer next term)
23(M) Tu 
12/13/05
(note: 1 day after "end of classes")
Darwinian evolution, population genetics and molecular evolution  (last lecture) P. Ch 23 (& Ch 1), & Ch 26
Rev session
(M)
TBA Review session (optional) Times & Rooms TBA 
  Tu 12/20/05 at 4:10 Exam #4.   EMPHASIZES LECTURES 20 - 23, but will refer back to entire course.
Important: This is not the usual date & time for a class that meets Tu-Th at 10:35. Please take this into account when buying tickets to go home.
 
    *Exams are designed to be completed in 75 minutes. Students with a class conflict at 5:40 AND 7:30, should  contact Dr. Chasin to search for an alternative.  
    **This lecture will be repeated Oct. 7, 2005 Friday,
 2:15-3:30 in 825 Mudd.