Biology C2005/F2401 - 2011 Intro Bio
Schedule of Lectures, recommended readings, exams, and download links   
Students with older editions of the texts can consult older reading lists and find the readings for the same topics.
To study lecture material in advance you may access those from last year which are usually very similar. 
See additional notes below.

    ++Download codes:

LH, lecture notes in html;
LP, lecture notes as pdf;
O, outline		 M,  mp3 audio of lecture
W, WMA audio of lecture;
Q,  QuickTime movie of eve. lec. PPT   ... .....sync'd to audio (new, experimental)
PP, PowerPoint used in lecture
NA, not available
   Lecture notes, recording, etc. added as we go.
Lecture:
(C)hasin
(M)owsh.		  Date  Subject of Lecture Recommended reading in Becker 8th ed. (B) or Savada 9th ed. (S) 

Downloads++
 
1 (C) Tu
9/6/11		 Introduction. Living things. Cells. Exponential growth. Water. B: Ch.1;Ch.2:18-32; Ch.4:75-79
S: Ch 1 + Ch 5.1+5.2		 LH LP PP M W Q H
2 (C) Th
9/8/11		 Water contd. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. B: Ch.3: 46-47; 60-66
S: Ch.2; Ch 3.1, 3.3 		LH  LP PP M W  Q H
3 (C) Tu
9/13/11		 Polysaccharides. Lipids. Phospholipids. Membranes. Amino acids.
 B: Ch.3: 65-70; Ch7: 167-173
S: Ch. 3.4; Ch 6: 105-108		 LH LP PP  M  W  Q
4 (C) Th
9/15/11		 Amino acids. Stereo-isomers.  Peptide bonds. Small molecule separation methods.
B: Ch.3: 41-48; Ch.2: 21-22
S: Ch. 3.2		 LH LP  PP  M  W Q H 
5 (C) Tu
9/20/11		 Protein structure start. Denaturation. Renaturation. Alpha helix. Beta sheet. 3-D structure. Quaternary structure. Subunit interaction. Domains.  B: Ch. 3: 48-54
S: Ch. 3.2 again		 LH LP PP  M  W Q H PDF of PPT
6 (C) Th
9/22/11		 Prosthetic groups. Membrane proteins. Catalysis. Enzymes. Protein purification methods. Chemical kinetics.
 B: Ch.7:161-162,179
S: Ch. 8:156-161		 LH  LP PP  M W NA  H 
7 (C) Tu
9/27/11		 Enzyme kinetics. Enzyme inhibitors. Feedback inhibition.   LH LP PP M W Q H
8 (C) Th 
9/29/11		 Free energy and the direction of chemical reactions. ATP hydrolysis. Glycolysis as a pathway in intermediary metabolism.  Anaerobiosis.  Fermentation.
 B: Ch.9: 224-238
S: Ch.9: 170-177		 LH LP  PP M  W  Q  H
Exam#1 Tu
10/4/1		 Exam #1.
Covers topics actually covered in lectures 1 - 7 inclusive.
Note exams are not at morning class times. 
Optional review session (questions answered) held at the morning class time and place.		 5:40 - 7:20 PM or 7:30 - 9:10M
See EXAM 1 INFO page for link to room and time assignments.
Email Paige Thompson
( [email protected] ) to request justified changes in exam room assignment		              
9 (C) Th
10/6/11		 Respiration. Electron transport. Oxidative phosphorylation. ATP synthase. Alternative energy sources. Biosynthetic pathways. B: Ch.10
S: Ch 7:150-157
Required: "Carbon" by P. Levi
optional skim: B:Ch.11/S:Ch.8		  LH LP PP M  W NA H

10 (M)		 Tu   
10/11/11
Drop deadline		 DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication B: Ch. 3:54-60 + Box 3A;Ch. 18:505-517
S: Ch. 4.1,
13.1 & 13.2  & fig. 14.8
Required: DNA Articles		 LH  LP Out M  W   H
-- Th
10/13/11		 No lecture today.
To compensate, a second lecture (#12) has been added on Tues. 10/18/11 following the usual lecture time. Two lectures (#11 & #12) will be given on 10/18. See below. 		               
11(M) Tu
10/18/11		 Wrap up of DNA structure; Details of DNA synthesis. The lecture at 5:40 pm will be in 417 IAB, not 309 Havemeyer. 
B: Ch. 19:551-567
S: Ch. 13.3 & 13.4		 LH LP Out M W   H
12 (M) Tu
10/18/11
7:15  repeated Fri. 10/21 am
 PCR
Transcription & the central dogma
Lecture 12 will be given twice afterall. The first time will be from 7:15 to 8:30 in 309 Havemeyer. It will be repeated on Friday, 10/21; 10:35 am to 11:50 in 309 Havemeyer.
 B: Box 19A
S: Ch. 13.5                            
B: Ch. 21: 645-660 & 674-end.
S: Ch. 14.1 -14.3		 LH LP Out M W   H
-- Th
10/20/11		 No lecture today.
To compensate, a lecture has been added at the end of the semester, on the first study day.		                
13 (M) Tu
10/25/11		 Wrap up of transcription; Intro to Translation and the genetic code. B: Ch. 22 to p. 693
S: Ch. 14.5 (14.6 next term)		 LH LP Out M W   H
Exam #2 Th
10/27/11		 Exam #2. Covers topics of lectures 8 - 12. Optional review session (questions answered) at morning class time and place. 5:40 - 7:20 PM and
7:30 - 9:10PM **
Room(s) TBA		              
14 (M) Tu
11/01/11		 Translation & the genetic code, cont. Mutation will be postponed to #15) 
B: Ch. 22: 693-695
S: Ch. 15.1		 LH LP Out M W    H
15 (M) Th
11/3/11		 Mutation & Regulation of protein synthesis in prokaryotes. B: Ch. 23 to p. 718.
S: Ch. 16.2		 LH  LP  Out M  W   H

 		 Tu 
11/8/11		 ELECTION DAY - NO CLASS                
16 (M) Th
11/10/11		 Bacterial and viral reproduction.
 		 B: Ch. 20: 620-624 & Box 18A (p.508-509)
S: Ch. 12.6 & 16.1		 LH LP  Out  M  W   H
17 (M) Tu
11/15/11		 Recombinant DNA technology I. Restriction enzymes & forensics. Blots and probes. B: Ch. 18: 518-520
& Boxes 18B & 18C
S: Ch. 15.2		 LH LP  Out M W   H
18 (M) Th
11/17/11
P/F deadline		 Recombinant DNA tech. II. Molecular cloning;

Discoveries about Eukaryotic gene/genome structure. Introns and exons. (This will be covered in '19; on exam #2.)

 B: Ch 20: 628-end.  
S. Ch. 18
B: Ch. 21: 669-674.
S: Ch. 14.4 		LH LP  Out M W   H
19 (M) Tu
11/22/11		 Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term); intro to meiosis B: Ch. 19: 549-551 & 571-580.
S: Ch. 11.1-11.3		 LH  LP  Out M W   H
  Th 11/24/11 Thanksgiving holiday                
20 (M) Tu
11/29/11		 Eukaryotic cell division II & Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and intro to simple inheritance. B: Ch. 20: to p 612.
S: Ch. 11.4-11.5		 LH LP  Out M W   H
Exam #3 Th
12/01/11		 Exam #3: Covers topics of lectures 13-18 (See Exam 3 Page for details -- will include wrap of genetic engineering in start of lect. 19).  Optional review session (questions answered) at morning class time and place. 5:40 - 7:20PM and
7:30 - 9:10M **
Room(s) TBA 		             
 21(M) Tu
12/06/11		 Eukaryotic Genetics I: One gene at a time. Crosses & Genetic diseases. B: Ch. 20: 612-618
S: Ch. 12.1, 12.2, & 12.4 pp. 256-259. (skip dihybrid crosses for now)		 LH LP Out M W   H
22 (M) Th
12/8/11		 Crosses with more than one gene at a time. Intro to Linkage and mapping B: Ch. 20: 618-620
S: Ch. 12.3 to 12.4; Ch. 15.3-15.6 		 LH LP Out  M W    H
23 (M) Tu
12/13/11		 Wrap up of linkage; Darwinian evolution, population genetics and molecular evolution  (last lecture; this is the day after the official last day of classes) PM lecture will be in 301 Pupin, not the usual room.
S: Ch. 1.1 & 1.2; Ch. 21 & Ch. 24 LH LP Out  M W   H
Review  (M)  TBA Optional, date and room TBA                
FINAL EXAM Tu
12/20/11
4:10-7:00
&7:10-10		 Exam #4.   EMPHASIZES LECTURES 19 - 23, but will refer back to entire course.
Important: This is not the usual date & time for a class that meets Tu-Th at 10:35 or 5:40. Please take this into account when buying tickets to go home.
 Rooms TBA 		              
Exams are designed to be completed in 75 minutes. Students with a class conflict at 5:40 exam may take the exam at 7:30 (requires permission including proof of class conflict: CU printout of schedule). Students with class conflicts at 5:40 AND 7:30 should contact Paige Thompson ([email protected]) to search for an alternative.

Download codes:

LH, lecture notes in html, best for viewing on a screen

LP, lecture notes as pdf, best for printing

M, audio of lecture in mp3 format

W, audio of lecture in WMA format

PP, PowerPoint, if used in lecture

Out, Outlines for lectures 10-end.

Q, QuickTime movie (.m4a) of PowerPoint synchronized with audio of evening lecture (~ 40 MB)

H, handouts of '11. Handouts of '10 are not linked in, but can be accessed in the handouts folder.


If you have trouble getting the m4a file to open in QuickTime by clicking in your browser, or the display is too small, save it to a folder on your computer, open QuickTime Player, and then open the lecX_10.m4a file in QuickTime.  QuickTime Player can be downloaded here (iTunes not needed). You may need v. 7.6.6 or later. 

Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. All of the 2010 lectures (on separate web page) are available for those who want to look ahead. There are links to figures in an older Purves (Savada) text embedded in the lectures.  Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject.
Savada and Purves refer to the same basic text: Sadava is the first author from the 8th edition on, Purves was the first author of editions 1-7.
Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures, the handouts, and the problems.  The texts should be used to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams.  You are only responsible for the links to the handouts, hard copies of which are provided in class.