Biology C2005/F2401 - 2010 Intro Bio
Schedule of Lectures, recommended readings, exams, and download links    Updated 12/09/2010 08:25 PM
Students with older editions of the texts can consult older reading lists and find the readings for the same topics:
To study lecture material in advance you may access those from last year which will be very similar. 
See additional notes below.

    ++Download codes:

LH, lecture notes in html;
LP, lecture notes as pdf;
O, outline.		 M,  mp3 audio of lecture;
W, WMA audio of lecture;
Q,  QuickTime movie of eve. lec. PPT   ... .....sync'd to audio (new, experimental);
PP, PowerPoint used in lecture.
 		    
Lecture:
 (C)hasin
(M)owsh.		  Date  Subject of Lecture (last updated 12/09/2010 08:25 PM) Recommended reading in Becker 7th ed. (B) or Savada 9th ed. (S) 

Downloads++
 
1 (C) Tu
9/7/10		 Introduction. Living things. Cells. Exponential growth. Water. B: Ch.1; Ch.2:18-31; Ch.4:75-79
 S: Ch 1 + Ch 5.1+5.2		 LH LP W M Q1 PP
2 (C) Th
9/9/10		 Water contd. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. Polysaccharides. B: Ch.3: 46-47; 61-66
S: Ch.2; Ch 3.1, 3.3 		LH LP W M na2 PP
3 (C) Tu
9/14/10		 Polysaccharides cont. Lipids. Phospholipids. Membranes. B: Ch.3: 66-71; Ch7: 167-173
 S: Ch. 3.4; Ch 6: 105-108		 LH LP W M na2 PP
4 (C) Th
9/16/10		 Amino acids. Stereo-isomers. Protein structure. Peptide bonds. Small molecule separation methods. B: Ch.3: 41-48; Ch.2: 21-22
S: Ch. 3.2		 LH LP W M Q3 PP
5 (C) Tu
9/21/10		 Alpha helix. Beta sheet. 3-D structure. Subunit interaction. Domains.  B: Ch. 3: 49-54
 S: Ch. 3.2 again		 LH LP W M Q PP
6 (C) Th
9/23/10		 Prosthetic groups. Membrane proteins. Catalysis. Enzymes. Protein purification methods. Chemical kinetics. B: Ch.7:161-162,179
 S: Ch. 8:156-161		 LH LP W M Q PP
7 (C) Tu
9/28/10		 Enzyme kinetics. Enzyme inhibitors. Feedback inhibition. Free energy and the direction of chemical reactions. ATP hydrolysis. B: Ch. 6; Ch.5
 S: Ch. 8: 161-165; 148-155		 LH LP W M na2 PP
8 (C)
Th 
9/30/10		 Glycolysis as a pathway in intermediary metabolism.  Anaerobiosis. Krebs (TCA) cycle. Electron transport. B: Ch.9: 224-237
 S: Ch.9: 170-177		 LH LP W M na2 PP
Exam#1 Tu
10/5/10		 Exam #1. Covers topics actually covered in lectures 1 - 7 inclusive. Note exams are not at morning class times. Optional review session (questions answered) at the morning class time and place. 5:40 - 7:20 PM or 7:30 - 9:10M
See EXAM1 INFO page for link to room and time assignments.
Email Jessie Kunkler([email protected]) to request justified changes in exam room assignment		            
9 (C) Th
10/7/10		 Oxidative phosphorylation. Alternative energy sources. Biosynthetic pathways.  B: Ch.10
S: Ch 7:150-157
 optional glance:B:Ch.11/S:Ch.8		 LH LP W M   PP

10 (M)

 

 Tu   
10/12/10
Drop deadline		 DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication B: Ch. 3:54-60 + Box 3A;Ch. 18:508-520
S: Ch. 4.1,
13.1 & 13.2  & fig. 14.8		 LH LP W M   O
11 (M) Th
10/14/10		 Wrap up of DNA structure; Details of DNA synthesis B: Ch. 19:553-566
S: Ch. 13.3 & 13.4		 LH LP W M   O
12(M) Tu
10/19/10		 PCR


Transcription & the central dogma

B: Box 19A
S: Ch. 13.5   

B: Ch. 21: 645-660 & 674-end.
S: Ch. 14.1 -14.3		 LH LP W M   O
13 (M) Th
10/21/10		 Wrap up of transcription; Intro to Translation and the genetic code. B: Ch. 22 to p. 692
S: Ch. 14.5 (14.6 next term)		 LH LP W M   O
14 (M) Tu
10/26/10		 Translation & the genetic code, cont.; Mutation (will finish in #15 if necessary)  
 		 B: Ch. 22: 692-695
S: Ch. 15.1		 LH LP W M   O
Exam #2 Th
10/28/10		 Exam #2. Covers topics of lectures 8 - 13. Optional review session (questions answered) at morning class time and place. 5:40 - 7:20 PM and
7:30 - 9:10PM **
Room(s) TBA		            
  Tu
11/02/10		 ELECTION DAY - NO CLASS              
15 (M)
 		 Th
11/4/10		 Regulation of protein synthesis in prokaryotes. B: Ch. 23 to p. 717.
S: Ch. 16.2		 LH LP W M   O
16 (M) Tu 
11/9/10		 Bacterial and viral reproduction.
 		 B: Ch. 20: 620-624 & Box 18A (p.511-512)
S: Ch. 12.6 & 16.1		 LH LP W M   O
17 (M) Th
11/11/10		 Recombinant DNA technology I. Restriction enzymes & forensics. Blots and probes. B: Ch. 18: 521-523
& Box 18C (530-531)
 S: Ch. 15.2		 LH LP W M   O
18 (M) Tu
11/16/10		 Recombinant DNA tech. II. Molecular cloning;

Discoveries about Eukaryotic gene/genome structure. Introns and exons.

 B: Ch 20: 629-end.  
S. Ch. 18
B: Ch. 21: 669-673.
S: Ch. 14.4 		LH LP W M   O
19 (M) Th
11/18/10
 P/F deadline		 Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term); intro to meiosis B: Ch. 19: 551-553 & 572-582.
S: Ch. 11.1-11.3		 LH  LP W M   O
20 (M) Tu
11/23/10		 Eukaryotic cell division II & Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and intro to simple inheritance. B: Ch. 20: to p 612.
S: Ch. 11.4-11.5		 LH  LP W M   O

 		 Th
11/25/10		 Thanksgiving holiday              
 21(M) Tu 11/3010 Eukaryotic Genetics I: One gene at a time. Crosses & Genetic diseases. B: Ch. 20: 612-618
S: Ch. 12.1, 12.2, & 12.4 pp. 256-259. (skip dihybrid crosses for now)		 LH  LP W M   O
Exam #3 Th
12/02/10		 Exam #3: Covers topics of lectures 14-18 (See Exam 3 Page for details).  Optional review session (questions answered) at morning class time and place. 5:40 - 7:20PM and
7:30 - 9:10M **
Room(s) TBA 		           
22 (M) Tu
12/07/10		 Crosses with more than one gene at a time. Intro to Linkage and mapping B: Ch. 20: 618-620
S: Ch. 12.3 to 12.4; Ch. 15.3-15.6 		LH  LP W M   O
23 (M) Th
12/9/10		 Wrap up of linkage; Darwinian evolution, population genetics and molecular evolution  (last lecture) S: Ch. 1.1 & 1.2; Ch. 21 & Ch. 24 LH  LP W M   O
Review  (M)  TBA Optional, date TBA              
FINAL EXAM Tuesday,
Dec. 21,
2010
4:10-7:00 		Exam #4.   EMPHASIZES LECTURES 19 - 23, but will refer back to entire course.
Important: This is not the usual date & time for a class that meets Tu-Th at 10:35. Please take this into account when buying tickets to go home.
 Rooms TBA 		            
***Exams are designed to be completed in 75 minutes. Students with a class conflict at 5:40 exam may take the exam at 7:30 (requires permission including proof of class conflict: CU printout of schedule). Students with class conflicts at 5:40 AND 7:30 should contact Jessie Kunkler ([email protected]) to search for an alternative.
*Download codes: LH, lecture notes in html, best for viewing on a screen; LP, lecture notes as pdf, best for printing; M, audio of lecture in mp3 format; W, audio of lecture in WMA format; PP, PowerPoint, if used in lecture; O, outlines for lectures 10-end.

Q, QuickTime movie (.m4a) of PowerPoint synchronized with audio of evening lecture (alpha version, new for 2010, ~ 40 MB)
If you have trouble getting the m4a file to open in QuickTime by clicking in your browser, or it is too small, then save it to a folder on your computer, open QuickTime Player, and then open the lecX_10.m4a file in QuickTime.  QuickTime Player can be downloaded here (Itunes not needed). You may need v. 7.6.6 or later. 

Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. All of the 2009 lectures (on separate web page) are available for those who want to look ahead. There are links to figures in an older Purves (Savada) text embedded in the lectures.  Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject.
Savada and Purves refer to the same basic text: Sadava is the first author from the 8th edition on, Purves was the first author of editions 1-7.
Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures, the handouts, and the  problems.  The texts should be used to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams.  You are only responsible for the links to the handouts, hard copies of which are provided in class.
1 Incomplete, only about 75% of morning lecture.  2Not available.  3Low volume; use headphones.