Biology C2006 / F2402 - Spring 2012 - Schedule  Last modified:   February 01, 2012

Lecture #
M = Mowsh.
F= Firestein
H = Heicklen

 Date

 Topic

Recommended reading
B = Becker, 8th ed (7th in paren. if dif. )  
S = Sadava/Purves  9th ed (8th in paren if dif.)
Sh = Sherwood, 6th ed. (5th in paren)
 

Dates for 2012 midterm exams are 2/9, 3/8, & 4/5. Final  5/10 (Thurs).
 Please plan carefully as there will be NO makeups. Please email Dr. M  or Paige <pnt2102@columbia.edu> immediately if you foresee any difficulties with these dates.

For 2011 notes and recommended readings in older editions of the texts see   2011 schedule or Older Schedules . For recordings of 2011 see lecture links '11
Detailed outlines for each lecture will be posted the day before (for Dr. M). Recordings of the lecture will be posted afterwards.
Readings will be updated for the 8th ed of Becker shortly
1  M Tu 1/17 Introduction to course; Overview of the Cell & Methods of Cell Biology
 
B: Ch.4
S: Ch.5 (4)
2 M Th 1/19
Cytoskeleton (for each euk. organelle, see appropriate part of Sa. Ch. 4.3)


Introduction to Membrane Structure (next time)
B: Ch.15 p. 422- 425 (425-427)& table 15-2, & p.442 (446)-end.
S: Ch. 5.3 (4.3)

B: Ch 7
S: Ch 6.1 & 6.2 (5.1 & 5.2)
3 M Tu 1/24 Membrane structure, Cell-cell junctions & the ECM (Junctions will be next time.) See above & B. Ch.17 p. 481-487 (484- 490).
4 M Th 1/26 Cell-cell junctions & the ECM ; Cell & tissue types

Transport of small molecules
S: Ch. 40.1 p. 835-838 (857-860)
See below.
5 M Tu 1/31 Transport of small molecules across membranes B: Ch.8
S: Ch. 6.3 & 6.4 (5.3 & 5.4)
6M Th 2/2 Transport of small molecules cont; Moving large molecules into (& out of) the cell; RME
 
B: Ch.12 esp. p. 341-355 (342-356)
S: Ch. 6.5 (5.5)
The readings in Becker below are for the 7th ed,. They will be updated for the 8th ed.shortly
7 M

 

Tu 2/7 Sorting of Proteins to their Proper Place -- Overview

Intro to Structure of Nucleus & Chromatin 

 


Transport into nuclei

B: Ch.22 p.696 (702) - end
S: Ch. 14.6 (12.5)

B: Ch.18 p. 530 - 538 (533 to 541)
S: Ch. 11.3, p. 215-216 (Ch 9.3 p. 187-188)

B: Ch.18 p.538 (541) - end
S. Ch. 5.3 (4.3)

*** Thurs 2/9 Exam #1 - Covers topics in lectures 1- 6 Review Session: 10:35 am
Exam times: 5:40 and 7:30 pm
8 M Tu 2/14 Chromatin Structure wrap up

Regulation of Eukaryotic Gene Activity

See above.

B: Ch. 23 p. 721- 731 (727-737)
 
9 M Th 2/16 Regulation of Eukaryotic Transcription  B: Ch. 23 p. 732 -744 (737-749)
S: Ch.16.3 & 16.4 (14.4)
10 M Tu 2/21 Post Transcriptional Regulation
 
B. Ch. 23 p. 744 (750)-end.
S: Ch.16.5 (14.5 & 14.6)
11 M Th 2/23 Role of ER in protein sorting; Roles of rest of endomembrane system (Golgi, lysosomes, etc.) B: Ch.12 & end Ch. 22
S: Ch. 5.3 & 14.6 (4.3 & 12.5)
12 M Tu 2/28 How proteins get to other organelles (mitochondria, peroxisomes, etc.)  
13 M Th 3/1 Chemical communication 1 -- signaling -- Types of signals & receptors. Intracellular receptors for lipid soluble signals; G Proteins & 2nd messengers

For Signaling overall: B. Ch. 14 & S. Ch. 7 (15); for hormones S. Ch. 41
B: Ch. 14 p. 392-406 (392-405)
S: Ch.7 (Ch.15)

S: Ch. 41, esp. 856-857 (878-879) -- receptors, & 861-863 (883-885) --thyroid

14 M Tu 3/6 Chemical communication 2 -- use of signals -- Homeostasis & Control of temperature
 

Control of Blood Glucose (if time)

S: Ch. 40.1 & 40.4;
Sh: Ch 1 (homeostasis)
Sh: Ch. 17 p. 641-end (654-end) (temp.)

Ch. 41.3 p. 864- 865 (887) & 51.4 p. 1086 (50.4 p. 1087)
Sh: Ch. 19 p. 701-716 (719-733)

  *** Thurs  3/8 Review Session & Exam #2 - Covers topics in lectures 7 - 13.  See Info for Exam #2 for details. Review Session: 10:35 am
Exam times: 5:40 and 7:30 pm
  3/13, 3/15 Spring Vacation  -  no class!  
The remaining schedule of lecture topics is tentative -- it will be finalized as soon as possible. The readings in Becker below are for the 7th ed,. They will be updated for the 8th ed.
15 M Tu 3/20 Animal Development 1 -- Stem cells
Note: This is the drop date for most schools
S: Ch. 19
16 M

 

Th 3/22 Animal Development 2 -- Sex Determination See above & S: Ch. 41.3 p. 867 (889)
17 F Tu 3/27 Electrical Communication 1  Notes are in word, not html For lect. 13 & 14, see B: Ch. 13 & S: Ch 45 (Ch 44)
18 F Th 3/29 Electrical Communication 2 Notes are in word, not html See above.
 19 M Tu 4/3 Wrap up of Electrical  Communication S: Ch. 46.1 (Ch 45.1) & figs. 47.1 & 47.10 (46.1 & 46.10)
  Thurs 4/5 Review Session & Exam #3 - Covers topics in lectures 14 -18 Review Session: 10:35 am
Exam times: 5:40 and 7:30 pm
20 M Tu 4/10 Organization of the Nervous System & Intro to
Effectors: Skeletal & Smooth Muscle
B: Ch. 16 p. 461-473 (461-475)
S: Ch. 48.1 & 48.2 (Ch 47.1 & 47.2)
21 M Th 4/12 Muscle contraction; heart & circulation (if time) See above & S: Ch 50.3 ( Ch 49.3)
22 M Tu 4/17 Hormones -- Major ones

 

Stress response: Co-ordination of nervous & hormonal signals

B: Ch. 14 p. 406-419 (405-419).
S: Ch. 41
Sh: Ch. 18

S: Ch. 41.3 p. 865-867 (887-888)  -- Stress
Sh: Ch. 19 p.698-701 (716-719)

23 M Th 4/19 Kidney Function -- Salt & Water Homeostasis


Intro to immune response next time

S: Ch. 52.4 -52.6 (Ch 51.4-51.6)

S: Ch. 42 ( Ch 18).

24 M Tu 4/24 Molec. & Cell. details of Immune Response
 
S: Ch. 42 (Ch 18).
25 M Th 4/26  Regulation of the Cell Cycle & Cancer.
 
B:  19 p. 582 -end (586-end) & Ch. 24
S: Ch. 11.2 (Ch 9.2) & Ch. 11.7 (Ch 17.4)
    5/1 to 5/3 Study Days. Optional Review before final TBA (prob. after study days)  
   Thurs 5/10 Exam #4 - EMPHASIZES LECTURES 19 - 24, but may refer back to the entire course. Exam will be at 4:10; later session for conflicts if needed. 6 pm for those in Sames' Orgo class.
Sherwood's Physiology  is completely optional, for those who like to read in more depth. See Textbooks for more details.