Lecture #	Date	Topic	Recommended reading	Html	Pdf	WMA	MP3
Dates for 2014 midterm exams are 2/13, 3/13, & 4/10. Exam #4 is 5/15 (All Thurs.) Please plan carefully as there will be NO makeups. Please email Dr. M or Paige <pnt2102@columbia.edu> immediately if you foresee any difficulties with these dates.
For 2013 notes, recordings, and recommended readings see 2013 schedule; for pages in older editions of the texts see Older Schedules . Detailed outlines/notes for each lecture will be posted the day before (for Dr. M). Recordings of the lecture will be posted afterwards.
1 M	Tu 1/21	Introduction to course; Overview of the Cell & Methods of Cell Biology	B: Ch.4 S: Ch.5 (4 in 8th)
2 M	Th 1/23	Cytoskeleton (for each euk. organelle, see appropriate part of Sa. Ch. 4.3) Introduction to Membrane Structure (maybe next time)	B: Ch.15 p. 422- 425 (425-427)& table 15-2, & p.442 (446)-end. S: Ch. 5.3 B: Ch 7 S: Ch 6.1 & 6.2
3 M	Tu 1/28	Membrane structure, Cell-cell junctions & the ECM	See above & B. Ch.17 p. 481-487 (484- 490)
4 M	Th 1/30	Cell-cell junctions & the ECM, cont.; Cell & tissue types Transport of small molecules	S. fig. 6.7 for junctions S: Ch. 40.1 & 40.2 (40.1) See below.
5 M	Tu 2/4	Transport of small molecules across membranes	B: Ch.8 S: Ch. 6.3 & 6.4
6M	Th 2/6	Transport of small molecules cont; Moving large molecules into (& out of) the cell; RME	B: Ch.12 esp. p. 341-355 (342-356) S: Ch. 6.5
7 M	Tu 2/11	Sorting of Proteins to their Proper Place -- Overview Intro to Structure of Nucleus & Chromatin; & Transport into nuclei	B: Ch.22 p.696 - end S: Ch. 14.6 B: Ch.18 p. 527 (530) to end S: Ch. 11.3, p. 211-213 (215-217)
***	Thurs 2/13	Exam #1 - Covers topics in lectures 1- 6	Review Session: 10:10 am Exam times: 5:40 and 7:30 pm
8 M	Tu 2/18	Role of ER in protein sorting; Roles of rest of endomembrane system (Golgi, lysosomes, etc.)	B: Ch.12 & end Ch. 22 S: Ch. 5.3 & 14.6
9 M	Th 2/20	How proteins get to other organelles (mitochondria, peroxisomes, etc.)	See above.
10 H	Tu 2/25	Chromatin Structure wrap up Regulation of Eukaryotic Gene Activity Note: This is the drop date for most schools	See above. B: Ch. 23 p. 722 - 732 (721- 731)
11 H	Th 2/27	Regulation of Eukaryotic Transcription	B: Ch. 23 p. 732 -744 S: Ch. 16.2 (16.3) & 16.4
12 M	Tu 3/4	Post Transcriptional Regulation	B. Ch. 23 p. 744-end. S: Ch.16.5
13 M	Th 3/6	Chemical communication 1 -- signaling -- Types of signals & receptors. Intracellular receptors for lipid soluble signals; G Proteins & 2nd messengers For Signaling overall: B. Ch. 14 & S. Ch. 7; for hormones S. Ch. 41	B: Ch. 14 p. 392-405 (406) S: Ch.7 S: Ch. 41.1 & section on thyroid 41.4 (41.3)
14 M	Tu 3/11	Chemical communication 2 -- use of signals -- Homeostasis & Control of temperature Control of Blood Glucose (if time)	S: Ch.40.1, 40.2, & 40.5 (40.1 & 40.4) Sh: Ch 1 (homeostasis) Sh: Ch. 17 p. 641-end (temp.) Ch. 41.4 (41.3) -section on insulin & glucagon & 51.4 Sh: Ch. 19 p. 701-716 (719-733)
*******	Thurs 3/13	Review Session & Exam #2 - Covers topics in lectures 7 - 13. See Info for Exam #2 for details.	Review Session: 10:10 am Exam times: 5:40 and 7:30 pm
	3/18, 3/20	Spring Vacation - no class!
Schedule up to here is firm. So is date of Exam #3. Order of remaining topics may be altered. Note that there is no class on Tu 4/15, and a makeup class is scheduled on Fri 4/4.
15 H	Tu 3/25	Animal Development 1 -- Stem cells	S: Ch. 19
16 H	Th 3/27	Animal Development 2 -- Sex Determination	See above & S: Ch. 41.4 (41.3) section on sex steroids.
17 M	Fri 3/28; Time & Place TBA	Hormones -- Major ones -- uses of chemical signaling	B: Ch. 14 p. 406-418 (406-419). S: Ch. 41 Sh: Ch. 18
18 M	Tu 4/1	Electrical Communication 1 Notes are in word, not html	For lect. 16 & 17, see B: Ch. 13 & S: Ch 45 (Ch 44)
19 M	Th 4/3	Electrical Communication 2 Notes are in word, not html	See above.
20 M	Tu 4/8	Wrap up of Electrical Communication Lactation & Stress response: Co-ordination of nervous & hormonal signals (if time)	S: Ch. 46.1 & figs. 47.1 & 47.9 (47.10) S: Ch. 41.4 (41.3) for stress Sh: Ch. 19
	Thurs 4/10	Review Session & Exam #3 - Covers topics in lectures 14 -19	Review Session: 10:35 am Exam times: 5:40 and 7:30 pm
	Tu 4/15	No class -- Jewish Holiday
21 M	Th 4/17	Organization of the Nervous System & Intro to Effectors: Skeletal & Smooth Muscle	B: Ch. 16 p. 460-470 (461-473) S: Ch. 48.1 & 48.2
22 M	Tu 4/22	Muscle contraction; heart & circulation (if time)	See above & S: Ch 50.3
23 M	Th 4/24	Kidney Function -- Salt & Water Homeostasis Intro to immune response (if time)	S: Ch. 52.4 -52.6 S: Ch. 42
24 M	Tu 4/29	Immune Response	S: Ch. 42
25 M	Th 5/1	Cancer & Regulation of the Cell Cycle	B: 19 p. 580 -end (582-end) & Ch. 24 S: Ch. 11.2 & Ch. 11.7
	5/6 to 5/8	Study Days. Optional Review before final TBA (prob. after study days)
	Thurs 5/15	Exam #4 - EMPHASIZES LECTURES 20 - 25, but may refer back to the entire course.	Exam will be at 4 pm; later session that day for conflicts if needed.
Sherwood's Physiology is completely optional, for those who like to read in more depth. See Textbooks for more details.
Textbooks: B = Becker, 8th ed (7th in paren. if dif. ) S = Sadava/Purves 10th ed (9th in paren if dif.) Sh = Sherwood, 6th ed. ; note that Silverthorn is equivalent
Lecturers: H = Heicklen; M = Mowshowitz
Lecture Formats: H = HTML; P = PDF
Recording Formats: W = WMA; M = MP3