Join a study to learn more about your bone health:

Cystic fibrosis related bone disease

We are looking for people with and without cystic fibrosis to determine the effect of the disease on bone.

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Treatment of Vitamin D Deficiency in patients with PHPT

We are recruiting women and men with primary hyperparathyroidism (PHPT).

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Study 3

More details coming soon.

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Cystic fibrosis related bone disease

Recent advances have improved the management of cystic fibrosis and increased the life expectancy for patients. However, there has been an increase in other medical complications such as bone disease. There are a higher number of fractures in people with cystic fibrosis compared to those without the disease; however, it is not clear how bone density and structure is changed by the disease.

We are recruiting women and men with and without cystic fibrosis.

You may be eligible if you are:
  • Between the ages of 18 and 50 years old
  • Interested in learning about your bone health
  • With or without cystic fibrosis
You are not eligible if you:
  • Have cancer
  • Are pregnant
  • Have a parathyroid disorder
A study visit involves:
  • A visit to Columbia University Medical Center for about 2 hrs
  • A bone health evaluation including imaging and blood tests

You will receive $25 to compensate for travel costs.

For more information please call 212-342-5725 or email Anna at: alk2186@cumc.columbia.edu

Download the full study brochure here.


Treatment of Vitamin D Deficiency in patients with PHPT

Many patients with mild Primary Hyperparathyroidism (PHPT) have Vitamin D deficiency. Both PHPT and Vitamin D deficiency can weaken bones and cause osteoporosis. Recent medical guidelines recommend treating patients with PHPT and low vitamin D levels with Vitamin D. Treatment with Vitamin D is particularly important in PHPT patients undergoing surgery to prevent postsurgical complications such as a low blood calcium. This study is designed to investigate the impact of two different Vitamin D repletion regimens over a 6 month period in patients with PHPT and low vitamin D.

We are recruiting women and men with PHPT.

You may be eligible if you have:
  • Primary Hyperparathyroidism
  • Low Vitamin D levels
You may not eligible if you have a history of:
  • Kidney or Liver disease
  • Long-term use of steroid medications, some anti-seizure medications or current use of Cinacalcet
  • Organ transplantation
  • GI diseases such as Crohn’s or Celiac Disease
  • Malignancy (other than cured basal or squamous cell skin carcinoma) within the last 5 years
  • Sarcoidosis
  • HIV/AIDS
This is a randomized controlled trial which means that you will either:
  1. Receive active Vitamin D treatment at baseline (80% of participants) + a daily multivitamin with Vitamin D
  2. OR

  3. Receive a placebo at baseline (20% of participants) + a daily multivitamin with Vitamin D

Group 1 or 2 assignment is by chance (randomized). Neither you nor your physician will know which group you are in until the 6 month time point.

This study involves:
  • Four visits to Columbia University Medical Center over 6 months
  • A bone health evaluation at no cost to you including bone density imaging, blood and urine tests at the baseline and 6 month study visits

You will receive $75 for completing each study visit—a total of $300 for completing all four study visits. After the 6 month study visit you will receive a copy of all study results.

For more information please call 212-342-5725 or email Anna at: alk2186@cumc.columbia.edu

Download the full study brochure here.


Study 3

More information coming soon.