ACADEMIC AND RESEARCH EXPERIENCE
Assistant Professor, Department of Chemistry, Columbia University, 2006-Present
Postdoctoral Fellow, Stanford University School of Medicine, 2000-2006
Mentor: Professor Joseph D. Puglisi
Graduate Student Researcher,
University of California, 1995-2000
Advisor: Professor Ignacio Tinoco, Jr.
TEACHING EXPERIENCE
Assistant Professor: 2006-Present
Graduate Biophysical Chemistry
Graduate Student Instructor:
1995-2000
Undergraduate Organic Chemistry II (Discussion Section)
Undergraduate Biophysical Chemistry II (Discussion Section)
Undergraduate Honors General Chemistry I (Laboratory and Discussion Section)
AWARDS AND HONORS
American Cancer Society Postdoctoral Fellowship,
2001-2005
UC Berkeley Outstanding Graduate Student Instructor Award,
1999
NIH Research Grant Supplement for Underrepresented Minorities,
1995-Present
Graduate Opportunity Program Fellow,
1995-1997
Florida International University Chemistry Department Outstanding Senior Award,
1995
ACS-Student Affiliate Outstanding Grant,
1995
Minority Biomedical Research Society Grant,
1994-1995
National Dean's List,
1990-1995
SOURCE OF INDEPENDENT FUNDING
Burroughs Wellcome Fund, Career Award in the Biomedical Sciences 2004
PROFESSIONAL SOCIETIES
American Chemical Society
Biophysical Society
American Association for the Advancement of Science
American Cancer Society
PUBLICATIONS
Gonzalez, R.L., Jr., Chu, S. and Puglisi, J.D. (2006). Direct
observation of allosteric during aminoacyl-tRNA delivery to the
ribosome. (Submitted)
Dorywalska, M., Blanchard, S.C.,
Gonzalez, R.L.,
Jr., Chu, S. and Puglisi, J.D. (2004). Site-specific labeling of 16S rRNA for single-molecule spectroscopy.
Nucleic Acids Res.
31, 182-189. [
PDF
]
Blanchard, S.C.,
Gonzalez, R.L.,
Jr., Kim, H.D., Chu, S. and Puglisi, J.D. (2004). tRNA selection and kinetic proofreading in translation.
Nat. Struct. Mol. Biol.
11, 1008-1014. [
PDF
] [
Supp Mat
]
Blanchard, S.C.*, Kim, H.D.*,
Gonzalez, R.L., Jr.*, Puglisi, J.D. and Chu, S. (2004). tRNA dynamics on the ribosome during translation.
Proc. Natl. Acad. Sci. USA,
101, 12893-12898. (*Equal Authorship) [
PDF
] [
Supp Mat
]
Lynch, S.R.,
Gonzalez, R.L.,Jr.
and Puglisi, J.D. (2003). Comparison of X-Ray Crystal Structure of
the 30S Subunit-Antibiotic Complex with NMR Structure of Decoding Site
Oligonucleotide Paromomycin Complex.
Structure,
11, 43-53. [
PDF
]
Gonzalez, R.L., Jr.
and Tinoco, I. Jr. (2000). NMR Spectroscopy Techniques for the
Identification and Characterization of Metal Ion Binding Sites in RNA.
Methods Enzymol.,
338, 421-443.
Yuen, H-W., Tinoco, I. Jr. and
Gonzalez, R.L., Jr.
(2000). The Effect of Magnesium(II) Ion and Cobalt(III) Hexammine Ion on an RNA Pseudoknot.
Berkeley Scientific,
4, 139-143.
Gonzalez, L.R.,Jr
and Tinoco, I. Jr. (1999). Solution Structure and Thermodynamics of a Divalent Metal Ion Binding Site in an RNA Pseudoknot.
J. Mol. Biol.,
289, 1267-1282. [
PDF
]
U.S. PATENTS PENDING
Gonzalez, R.L., Jr, Blanchard, S.C. and Puglisi, J.D. (Filed 27 January 2003). Surface Based Translation System
Gonzalez, R.L., Jr, Blanchard, S.c. and Puglisi, J.D. (Filed 27 January 2003). Translational Profiling
[
PDF Form of Ruben's CV]