Gibney Lab Columbia University Department of Chemistry


1. Lah, M. S.; Gibney, B. R.; Tierney, D. L.; Penner-Hahn, J. E.; Pecoraro, V. L. "The Fused Metallacrown Anion Na2{[Na0.5[Ga(salicylhydroximate)]4]2(m2-OH)4}- is An Inorganic Analogue of a Cryptate" J. Am. Chem. Soc. 1993, 115, 5857-5858.


2. Gibney, B.R.; Stemmler, A.J.; Pilotek, S.; Kampf, J. W.; Pecoraro, V.L. "Generalizing the Metallacrown Analogy: Ligand Variation and Solution Stability of the V(V)O 9-Metallacrown-3 Structure Type" Inorg. Chem. 1993, 32, 6008-6015.

3. Gibney, B. R.; Kessissoglou, D. P.; Kampf, J. W.; Pecoraro, V. L. "Copper(II) 12-Metallacrown-4: Synthesis, Structure, Ligand Variability and Solution Dynamics in the 12-MC-4 Structural Motif" Inorg. Chem. 1994, 33, 4840-4849.

4. Gibney, B.R.; Mulholland, S.E.; Rabanal, F.; Dutton, P. L. "Design of Synthetic Iron-Sulfur Proteins", Photosynthesis: from Light to Biosphere, P. Mathis, Ed., Vol. II, Kluwer Press, Boston, 1995, 645-648.

5. Gibney, B. R.; Pecoraro, V. L. "Theoretical Aspects of Metal Ion Interactions with Synthetic Carrier Ligands", Handbook on Metal-Ligand Interactions in Biological Fluids, Berthon, G., Ed., Vol. 1, Marcel-Dekker, New York, 1995, 62.

6. Pecoraro, V. L.; Gibney, B. R. "Structural Aspects of Selectivity in Metal-Ligand Interactions In Vivo", Handbook on Metal-Ligand Interactions in Biological Fluids, Berthon, G., Ed., Vol. 1, Marcel-Dekker, New York, 1995, 597.

7. Gibney, B. R.; Mulholland, S. E.; Rabanal, F.; Dutton, P. L. "Ferredoxin and Ferredoxin-Heme Maquettes", Proc. Nat. Acad. Sci. U.S.A., 1996, 93, 15041-15046. (PDF)

8. Gibney, B. R.; Wang, H.; Kampf, J. W.; Pecoraro, V. L."Structural Evaluation and Solution Integrity in the Manganese 12-MC-4 Structural Type", Inorg. Chem., 1996, 35, 6184-6193.(PDF)

9. Pecoraro, V. L.; Stemmler, A. J.; Gibney, B. R.; Bodwin, J. J.; Wang, H.; Kampf, J. W.; Barwinski, A. "Metallacrowns: A New Class of Molecular Recognition Agents", Prog. Inorg. Chem., K. Karlin, ed., Vol. 45,Chapter 2, Pergamon Press, 1996, 83-177.

10. Gibney, B. R.; Skalicky, J. J.; Rabanal, F.; Wand, A. J.; Dutton, P. L. "Design of a Unique Scaffold for Maquettes", J. Am. Chem. Soc., 1997, 119, 2323-2324.(PDF)

11. Gibney, B. R.; Johansson, J. S.; Rabanal, F.; Skalicky, J. J.; Wand, A. J.; Dutton, P. L. "Global Topology & Stability, Local Structure & Dynamics in a Synthetic Spin Labeled Four-Helix Bundle Protein", Biochemistry, 1997, 36, 2798-2806.(PDF)

12. Gibney, B. R.; Rabanal, F.; Dutton, P. L. "Synthesis of Novel Proteins", Curr. Opin. Chem. Biol., 1997, 1, 537-542.

13. Johansson, J. S.; Gibney, B. R.; Rabanal, F.; Reddy, K. S.; Dutton, P. L. "A Designed Cavity in the Hydrophobic Core of a Four-a-Helix Bundle Improves Volatile Anesthetic Binding Affinity", Biochemistry, 1998, 37, 1421-1429.(PDF)

14. Pilloud, D.L.; Rabanal, F.; Gibney, B. R.; Farid, R. S.; Moser, C. C.; Dutton, P. L. "Self-Assembled Monolayers of Synthetic Hemoproteins on Silanized Quartz", J. Phys. Chem. B, 1998, 102, 1926-1937. (PDF)

15. Gibney, B. R.; Rabanal, F.; Reddy, K. S.; Dutton, P. L. "Effect of Four Helix Bundle Topology on Heme Binding and Redox Properties", Biochemistry, 1998, 37, 4635-4643.(PDF)

16. Johansson, J. S.; Gibney, B. R.; Skalicky, J. J.; Wand, A. J.; Dutton, P. L. "A Native-Like Three-a-Helix Bundle Protein From Structure Based Redesign: A Novel Maquette Scaffold", J. Am. Chem. Soc., 1998, 120, 3881-3886.(PDF)

17. Skalicky, J. J.; Bieber, R. J.; Gibney, B. R.; Rabanal, F.; Dutton, P. L.; Wand, A. J. "Sequence-Specific Resonance Assignments for a Designed Four-a -Helix Bundle Protein", Journal of Biomolecular NMR, 1998, 11, 227-228.

18. Sharp, R. E.; Palmitessa, A.; Gibney, B. R.; Moser, C. C.; Daldal, F; Dutton, P. L. "Non-inhibiting perturbation of the primary energy conversion site (Qo site) in Rhodobacter capsulatus ubiquinol: cytochrome c oxidoreductase", FEBS Lett., 1998, 431, 423-426.

19. Mulholland, S. E.; Gibney, B. R.; Rabanal, F.; Dutton, P. L. "Characterization of the Fundamental Protein Ligand Requirements of [4Fe-4S]2+/+ Clusters Using Sixteen Amino Acid Peptide Maquettes", J. Am. Chem. Soc., 1998, 120, 10296-10302. (PDF)

20. Valkova-Valchanova, M.; Saribas, A.S.; Gibney, B. R.; Dutton, P. L.; Daldal, F. "Isolation and Characterization of a Two Subunit Cytochrome b-c1 Subcomplex from Rhodobacter capsulatus and Reconstitution of its Ubiquinone Oxidation (Qo) Site with purified Fe-S Protein Subunit", Biochemistry, 1998, 37, 16242-16251. (PDF)

21. Daniels, S.B.; Hantman, S.F.; Solé, N. A.; Gibney, B. R.; Rabanal, F.; Kates, S.A. "PioneerTM: A Continuous-flow Peptide Synthesis System", Peptides 1996, Ramage, R.; Epton, R. eds.; Mayflower Scientific, Ltd.; Kingswinford, England, 1998, 323-324.

22. Sharp, R. E.; Palmitessa, A.; Gibney, B. R.; White, J.L.; Moser, C. C.; Daldal, F; Dutton, P. L. "The ubiquinone Binding Capacity of Rhodobacter capsulatus Cytochrome bc1 Complex: Effect of Diphenylamine, A Weak Qo site Inhibitor", Biochemistry, 1999, 38, 3440-3446.(PDF)

23. Sharp, R. E.; Palmitessa, A.; Gibney, B. R.; Moser, C. C.; Daldal, F; Dutton, P. L. "Correlation Between Cytochrome bc1 Structure and Function: Kinetic and Spectroscopic Observations on Qo Site Occupancy and Dynamics", The Phototrophic Prokaryotes - Proceedings of the IX Int. Symp. on Phototrophic Prokaryotes, Peschek, G. A.; Loefflhardt, W.; Schmetterer, G. eds., Plenum, New York, 1999, 241-250.

24. Skalicky, J. J.; Gibney, B. R.; Rabanal, F.; Bieber-Urbauer, R. J.; Dutton, P. L.; Wand, A. J. "Solution Structure of a designed four-a-helix bundle maquette scaffold", J. Am. Chem. Soc., 1999, 121, 4941-4951.(PDF)

25. Gibney, B. R.; Rabanal, F.; Skalicky, J. J.; Wand, A. J.; Dutton, P. L. "Iterative Protein Redesign", J. Am. Chem. Soc., 1999, 121, 4952-4960. (PDF)

26. Mulholland, S. E.; Gibney, B. R.; Rabanal, F.; Dutton, P. L. "Determination of Non-Ligand Amino Acids Critical to [4Fe-4S]2+/+ Assembly in Ferredoxin Maquettes", Biochemistry, 1999, 38, 10442-10448.(PDF)

27. Gibney, B. R.; Dutton, P. L. "Histidine Placement in De novo Designed Heme Proteins", Protein Science, 1999, 8, 1888-1898.

28. Sharp, R.E.; Moser, C.C.; Gibney, B. R.; Dutton, P. L. "Primary Steps in the Energy Conversion Reactions of the Cytochrome bc1 Complex Qo Site", J. Bioenerg. Biomembr., 1999, 31, 225-233.(PDF)

29. Sharp, R.E.; Palmitessa, A.; Gibney, B. R.; Moser, C.C.; Dutton, P. L. "Probing the ubiquinone primary energy conversion site in the Rhodobacter capsulatus cytochrome bc1 complex", Biochemical Society Transactions, 1999, 27, 572-576.

30. Chen, X.; Moser, C. C.; Pilloud, D.L.; Gibney, B. R.; Dutton, P. L. "Engineering Oriented Heme Protein Maquette Monolayers Through Surface Charge Distribution Patterns", J. Phys. Chem. B, 1999, 103, 9029-9037. (PDF)

31. Sharp, R.E.; Gibney, B. R.; Palmitessa, A.; White, J.L.; Dixon, J.; Moser, C.C.; Daldal, F.; Dutton, P. L. "Effect of Inhibitors on the Ubiquinone Binding Capacity of the Primary Energy Conversion Site in Rhodobacter capsulatus Cytochrome bc1 Complex", Biochemistry, 1999, 38, 14973-14980.(PDF)

32. Moser, C.C.; Sharp, R.E.; Gibney, B. R.; Isogai, Y.; Dutton, P. L. "Synthetic protein maquette design for light activated intraprotein electron transfer" in Photosynthesis: Mechanisms and Effects, 1999, G. Garab, Ed., Kluwer Academic Publishers, Dordrecht.

33. Sharp, R.E.; Palmitessa, A.; Gibney, B. R.; White, J.L.; Wan, J. T.; Moser, C.C.; Daldal, F.; Dutton, P. L. "Probing the cytochrome bc1 complex Qo site mechanism using weak binding inhibitors" in Photosynthesis: Mechanisms and Effects, 1999, G. Garab, Ed., Kluwer Academic Publishers, Dordrecht..

34. Ugulava, N.B.; Gibney, B. R.; Jarrett, J.T. "Iron-Sulfur Cluster Interconversion in Biotin Synthase: Dissassociation and Reassociation of Iron is Required for Conversion of [2Fe-2S] to [4Fe-4S] Clusters" Biochemistry, 2000, 39, 5206-5214.(PDF)

35. Gibney, B. R.; Isogai, Y.; Reddy, K. S.; Rabanal, F.; Grosset, A. M.; Moser, C. C.; Dutton, P. L. "Comparison of Heme A and Heme B in a designed four-a-helix bundle: Implications for a Cytochrome c Oxidase Maquette", Biochemistry, 2000, 39, 11041-11049.(PDF)

36. Dutton, P.L.; Ohnishi, T.; Darrouzet, E.; Leonard, M.A.; Sharp, R.E.; Gibney, B. R.; Daldal, F.; Moser, C.C. "Coenzyme Q Oxidation-Reduction Reactions in Mitochondrial Electron Transport", Chapter 4 in Coenzyme Q: Molecular Mechanisms in Health and Disease, Quinn, P.E.; Kagan, V.J. eds., CRC Press, Boca Raton, Fl., 2000, 65-82.

37. Shifman, J.M; Gibney, B. R.; Sharp, R.E.; Dutton, P.L. "Heme Redox Potential Control in de novo Designed Four-a-Helix Bundle Proteins", Biochemistry, 2000, 39, 14813-14821. (PDF)

38. Gibney, B. R.; Dutton, P.L. "De novo Design and Synthesis of Heme Proteins" Adv. Inorg. Chem., Mauk, A. G.; Sykes, A. G. eds., Academic Press, New York, 2001, vol 51, 409-455.

39. Grosset, A.M.; Gibney, B. R.; Rabanal, F.; Moser, C.C.; Dutton, P.L "Proof of Principle in a De Novo Designed Synthetic Protein Maquette: An Allosterically Regulated, Charge Activated Conformational Switch in a Tetra-a-Helix Bundle", Biochemistry, 2001, 40, 5474-5487.(PDF)

40. Kennedy, M.L.; Silchenko, S.; Houndonougbo, N.; Gibney, B. R.; Dutton, P.L.; Rodgers, K. R.; Benson,D. R. "Model Hemoprotein Reduction Potentials: The Effects of Histidine to Iron Coordination Equilibrium ", J. Am. Chem. Soc., 2001, 123, 4635-4636.(PDF)

41. Ugulava, N.B.; Gibney, B. R.; Jarrett, J.T. "Biotin Synthase Contains Two-Distinct Iron-Sulfur Cluster Binding Sites: Chemical and Spectroelectrochemical Analysis of Iron-Sulfur Cluster Interconversions", Biochemistry, 2001, 40, 8343-8451.(PDF)

42. Kennedy, M.L.; Gibney, B.R. "Metalloprotein and Redox Protein Design" Curr. Opin. Struct. Biol. 2001, 11, 485-490.(PDF)

43. Gibney, B. R.; Huang, S.S.; Skalicky, J. J.; Fuentes, E.J.; Wand, A. J.; Dutton, P. L. "Hydrophobic Modulation of Heme Properties in Heme Protein Maquettes", Biochemistry, 2001, 40, 10550-10561. (PDF)

44. Chen, X.; Discher, B.M.; Pilloud, D.L.; Gibney, B. R.; Moser, C.C.; Dutton, P. L. "De novo Design of a Cytochrome b Maquette for Electron Transfer and Coupled Reactions on Electrodes", J. Phys, Chem. B, 2002, 106, 617-624. (PDF)

45. Daugherty, R.G.; Wasowicz, T.; Gibney, B.R.; DeRose, V.J. "Design and Spectroscopic Characterization of Peptide Models for the Plastocyanin Copper-binding Loop", Inorg. Chem. 2002, 41, 2623-2632. (Featured on Cover of Issue) (PDF)

46. Kennedy, M.L.; Gibney, B.R. "Proton Coupling to [4Fe-4S] 2+/+ and [4Fe-4Se]2+/+ Oxidation/Reduction in a Designed Protein" J. Am. Chem. Soc., 2002, 124, 6826-6827.(PDF)

47. Privett, H.K.; Reedy, C.J.; Kennedy, M.L.; Gibney, B.R. "Nonnatural Amino Acid Ligands in Heme Protein Design", J. Am. Chem. Soc., 2002, 124, 6828-6829. (PDF)

48.Gibney, B.R.; Pecoraro, V.L. "Use of Salicyl- and Napthoylhydroxamate Complexes in Preparation of Manganese and Copper 12-Metallacrown-4 Complexes: Mn(II)(Acetate)2 [Mn(III)(Salicylhydroximate)] 4 and (tetramethylammonium)2 [Cu(II)5(napthoylhydroximate) 4]," Inorganic Syntheses, vol. 33, McGraw-Hill Book Company, Inc., New York, 2002, 70-74.

49. Huang, S.S.; Gibney, B.R.; Stayrook, S.E.; Dutton, P.L.; Lewis, M. "X-ray Structure of a Maquette Scaffold" J. Mol. Biol., 2003, 326, 1219-1225. (PDF)

50. Reedy, C.J.; Kennedy, M.L.; Gibney, B.R. "Thermodynamic Characterization of Ferric and Ferrous Haem Binding to a Designed Four-a-Helix Protein" Chem. Commun., 2003, 570-571. (PDF)

51. Gibney, B.R. "Iron-Sulfur Protein Design" ChemTracts-Inorganic Chemistry, 2003, 16, 263-271 (Invited Group Highlight).