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The toxic state -- what form did it take?

You lose hair, for instance. I think methotrexate gives you loss of hair -- either methotrexate or cytoxan. It's methotrexate. And it can also produce nausea and vomiting. They're tough drugs to take, many of them. Cytoxan is less toxic, especially in small doses.

But they have to be given in combinations to be effective.

You can get a 50% improvement in recurrence; so that 50% fewer people recur with just L-PAM alone. But you can get a 93% prevention of recurrence with the combination.

So this has inspired quite a few workers, although far from everybody knows about it or is doing it.

Curiously enough, when these breast cancer figures were brought out was the day of Mrs. Ford's operation.

This was in the fall, wasn't it?

In the fall. And the next time they tried to do something about publicizing the figures, Mrs. Rockefeller had an operation for cancer, and the whole business about what to do or anything new about treatment was smothered by the fact of the operations. A very strance concatenation of circumstances.