Processing in the probed-sinewave paradigm is likely retinal

S. Sabina Wolfson & Norma Graham (2001)

Visual Neuroscience, 18(6), 1003-1010

reprint (pdf 2.5M)

In the probed-sinewave paradigm -- used to study the dynamics of light adaptation -- a small probe of light is superimposed on a sinusoidally flickering background. Detection threshold for the probe is measured at various times with respect to the flickering background. Here we present such stimuli using three methods: monoptic (the probe and the flickering background are presented to the same eye), dichoptic (the probe is presented to one eye and the flickering background is presented to the other eye), and binocular (the probe and the flickering background are both presented to both eyes). The results suggest that the processing associated with detecting the probe is primarily in the retina (or any place with monocular input). However, the results also suggest a slight amount of processing in the cortex (or any place with binocular input), particularly at the higher frequency of flickering background used here (9.4 Hz versus 1.2 Hz). A simple schematic model with three ocular dominance channels is consistent with the results.

Supported in part by NIH grants EY08459 to Norma Graham and EY06933 to Sabina Wolfson.