Post Partum Depression: Treatment

1. How do you define postpartum emotional disorder and what are their symptoms?

2. I'm a pediatrician, not a psychiatrist or an OB – do I actually have a role in diagnosing PPD?

3. But how do I diagnose post-partum depression?

4. OK….so I diagnosed the patient in the vignette above with postpartum depression. Now what do I do?

5. Will the mother be permanently depressed?


Contents

1. How do you define postpartum emotional disorders and what are their symptoms?

As mentioned above, the three postpartum emotional disorders are postpartum blues, postpartum depression, and postpartum psychosis. Postpartum blues describes the weeping and emotional lability which occur within the first two weeks postpartum. It is a normal condition of heightened emotions. Symptoms include frequent and prolonged crying, irritability, poor sleep, food cravings/loss of appetite, mood changes, and a sense of vulnerability. Symptoms generally resolve by postpartum week three. Postpartum depression is still a poorly defined syndrome, generally understood as unusually severe or prolonged postpartum blues. Symptoms of depression are generally noted at 4-8 weeks postpartum and include despondency, tearfulness, anhedonia, feelings of inadequacy, guilt, severe anxiety, irritability, change in appetite, difficulty concentrating, and fatigue. Often the mother will make multiple phone calls or visits to the pediatrician for trivial complaints. Some mothers will even develop obsessive thought patterns about their child’s health. Untreated, postpartum depression will last 3-14 months. Postpartum psychosis is obviously the most severe of the three disorders and is defined by the development of disordered thought processes. Symptoms begin within several days of delivery and may include confusion, disorientation, manic behavior, agitation, hallucinations, and delusions. Postpartum psychosis is a medical emergency where infanticide is a small but very real risk! Immediate hospitalization of the mother is required.



2. I’m a pediatrician, not a psychiatrist or an OB – do I actually have a role in diagnosing PPD?

Absolutely. First of all, the presence of maternal PPD can have a significant impact on your patient – the child. Maternal PPD can significantly negatively impact maternal-infant interaction and bonding. Other studies have shown that maternal depression correlates with developmental and behavioral difficulties throughout childhood, including the development of conduct and attention disorders. Maternal PPD can also lead to impairments in social and cognitive development through age four, as shown in certain studies by a decrease in intelligence test scores. (Seidman, 1998). Secondly, many mothers do not recognize their problem as depression and therefore do not seek help. The new mother may also feel shame and guilt about her feelings and will not discuss her feelings with anyone, especially her child’s doctor. Also, she may not be aware that help is readily available. Lastly, as mentioned above, you, as the pediatrician, see the mother more than any other health professional (the postpartum OB visit is at 6 weeks only) and therefore are more likely detect the presence of PPD.

 


3. But how do I diagnose post-partum depression?

There will be cases (as in the vignette) where it is obvious that there is something amiss. In such cases, a reasonable first question, even prior to asking any questions about the baby, is “How are you doing – you seem very sad/ upset/ tired?” or open up the conversation with “What a beautiful baby – it’s tiring/ challenging to have a new baby at home isn’t it?” For other cases, a very simple screening tool has been developed for the diagnosis of postpartum depression. The tool is called the Edinburgh Postnatal Depression scale, and studies have shown it to predict up to 50% of cases of PPD. A study by Evins et al. showed that in an OB/GYN residency program, the incidence of detection of PPD was significantly higher when the Edinburgh was used compared to the incidence of spontaneous detection during the course of the interview (35.4% vs. 6.3%). This screen consists of ten questions that screen for anhedonia, guilt, anxiety, coping ability, insomnia, feelings of despondency, and suicidality. The responses are scored from zero to three points where a response earning zero points indicates a total lack of the above feelings whereas a score of three indicates that the mother is experiencing these feelings very often. A total score of 10 or more is suggestive of postpartum depression. The screen should be performed at the 2 week, 2 month, and 4 month visits. See below for a copy of the screen.



4. OK….so I diagnosed the patient in the vignette above with postpartum depression. Now what do I do?

First and foremost, gently tell the mother that the symptoms she is experiencing are consistent with a postpartum emotional disorder. Remind her that this is very common and does not mean that she is “crazy.” For a woman with postpartum blues, this may be sufficient. In addition, there are national and international postpartum support groups that can be contacted. The two largest groups are Postpartum Support International (http://www.chss.iup.edu/postpartum) and Depression after Delivery (http://www.depressionafterdelivery.com).

For more difficult cases referrals should be made to a support group such as one that is currently being formed through the Alianza Dominicana and/or to a psychiatrist. If possible, urge the mother to find someone to help her with the newborn to remove some of the emotional and physical strain. If the psychiatrist deems it necessary, pharmacologic therapy may be initiated. Sertraline (Zoloft) seems to be the drug of choice as it is not excreted in breast milk, thus allowing nursing to continue. If your patient is started on an SSRI, remind them that it may take 1-3 weeks before any improvement is noted.

 


 

5. Will the mother be permanently depressed?

Most mothers recover completely, although some mothers with postpartum psychosis never fully recover. 60% of women with postpartum depression will have a recurrence with subsequent pregnancies. Interestingly, if treatment with an anti-depressant is begun within 24 hours of delivery that risk is reduced to only 6.7%.