Calculation Estimated GFR

• MDRD equation: GFR, in mL/min per 1.73 mm2

• GFR =   186.3 X ((serum creatinine) exp[-1.154]) X (Age exp[-0.203]) X (0.742 if female) X (1.21 if African American)

• Cockcroft-Gault equation: ml/min

• GFR= (140 – Age )X Wt kg/ (serum creatinine X 72)

• X (0.85 if female)

• Creatinine production is determined by muscle mass. Serum creatinine must always be interpreted with respect to patient's weight, age, and sex. The ADQI consensus committee on ARF favors the Modification of Diet in Renal Disease (MDRD) equation to estimate GFR (70 mL/min per 1.73 mm2 is considered the lower limit of normal).