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Measurement Issues in Substance Use and Psychiatric Disorders |
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A wide variety of studies have been conducted on reliability and validity of substance use and psychiatric disorders. These studies have been conducted in clinical, community and national samples, in the U.S. and abroad. The work has been funded by the National Institute on Drug Abuse ( NIDA ) and the National Institute on Alcohol Abuse and Alcoholism ( NIAAA ).
Findings from this research include:
DSM-IV alcohol and drug dependence showed good validity in U.S. community and national samples, as well as in a study conducted in several countries under the auspices of the World Health Organization.
DSM-IV alcohol abuse consistently showed lower reliability and validity than dependence when assessed hierarchically to dependence, as required in DSM-IV
The Psychiatric Research Interview for Substance and Mental Disorders (PRISM) showed better test-retest reliability for many disorders in samples of substance abusers than other diagnostic instruments tested in similar types of samples.
The Alcohol Use Disorders and Associated Disabilities Interview Schedule (AUDADIS) measures of alcohol and drug dependence and consumption patterns showed good to excellent test-retest reliability in various clinical samples.
Using comparative model-fitting, a continuous measure of alcohol dependence defined by number of criteria fit better than a categorical alcohol dependence variable dichotomized at any point, as illustrated in national data.
Using MPlus software with data from the NLAES survey, exploratory and confirmatory latent variable analysis indicated that DSM-IV marijuana abuse and dependence formed separate although correlated factors. DSM-IV cocaine abuse and dependence criteria formed similar patterns.
Not all individuals who meet criteria for DSM-IV alcohol dependence also manifest alcohol abuse, particularly women and minorities. This has implications for both screening in epidemiologic studies and for selection of phenotypes in genetics research.
Topics of current investigation in this area include a test-retest study of an updated version of the PRISM, and computerization of diagnostic interviews to improve ease of administration, reduce administration time, and improve reliability. This research is currently supported by the National Institute on Drug Abuse ( NIDA ) and the National Institute on Alcohol Abuse and Alcoholism ( NIAAA ).
Selected Publications:
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Hasin D, Samet S, Nunes E, Meydan K, Matsoeane K, Waxman R: Diagnosis of Comorbid Disorders in
Substance Users: Psychiatric Research Interview for Substance and Mental Disorders (PRISM-
IV). In press, Am J Psychiatry
Hasin D, Schuckit M, Martin CS, Grant BG, Bucholz KK, Helzer JE: The validity of DSM-IV alcohol dependence: what do we know and what do we need to know? Symposium, Research Society on Alcohol Scientific Meeting, June, 2002. Alcoholism: Clinical and Experimental Research. 27:244-252, 2003. Hasin D: Classification of alcohol use disorders. Alcohol Research & Health 27: 5-17, 2003. PDF Hasin DS, Grant BF, Liu X: DSM-IV alcohol dependence: a categorical or continuous phenotype? Submitted. Hasin DS, Grant BF: The co-occurrence of DSM-IV alcohol abuse in DSM-IV alcohol dependence: NESARC results on heterogeneity that differs by population subgroup. Submitted. Hasin D, Paykin A: Alcohol dependence and abuse diagnoses: concurrent validity in a nationally representative sample. Alcoholism: Clinical and Experimental Research 23:144-150, 1999. Hasin D, Grant B, Cottler L, Blaine J, Towle L, Ustun T, Sartorius N: Nosological comparisons of alcohol and drug diagnoses: a multisite, multi-instrument international study. Drug and Alcohol Dependence 47: 217-226, 1997. Hasin D, Carpenter K, McCloud S, Smith M, Grant B: The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): reliability of alcohol and drug modules in a clinical sample. Drug and Alcohol Dependence 44:133-141, 1997. PDF Hasin D, Trautman K, Miele G, Samet S, Smith M, Endicott J: Psychiatric Research Interview for Substance and Mental Disorders (PRISM): Reliability for substance abusers. American Journal of Psychiatry 153:1195-1201, 1996. PDF |
Choose another research area: Genetics and epidemiology of alcohol consumption and dependence symptoms in Israel
Natural history of alcohol use disorders
Comorbidity of psychiatric and substance use disorders
NYSPI/Columbia University |
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New York, New York 10032 |
Tel. (212) 543-5035 |
E-mail: dsh2@columbia.edu |