Measurement Issues in Substance Use and Psychiatric Disorders
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A wide variety of studies have been conducted on reliability and validity of substance use and psychiatric disorders in clinical, community and national samples, in the U.S. and abroad. The work has been funded by the National Institute on Drug Abuse ( NIDA ) and the National Institute on Alcohol Abuse and Alcoholism ( NIAAA ).
Findings from this research include:
DSM-IV alcohol and drug dependence showed good validity in U.S. and international community and national samples, while DSM-IV alcohol abuse showed lower and more variable reliability and validity when assessed hierarchically to dependence, as required in DSM-IV.
The Psychiatric Research Interview for Substance and Mental Disorders (PRISM) showed better test-retest reliability for psychiatric disorders than other diagnostic instruments in samples of substance abusers. This interview is now fully computerized and training is available.
Incorrect assumptions that all individuals who meet criteria for DSM-IV alcohol or drug dependence also experience abuse criteria have serious implications for screening in epidemiologic studies and for selection of phenotypes in genetics research, particularly among women and minorities.
Using different analytic strategies, alcohol and cannabis abuse and dependence criteria form a continuous underlying trait.
Nicotine dependence criteria and craving form a unidimensional latent trait with three DSM-IV "abuse" criteria: hazardous use, social/interpersonal problems, and interference with main role functioning.
Topics of current investigation in this area include studies of whether the proposed new criterion set for DSM-5 substance use disorders offer improvements over DSM-IV dependence.
Shmulewitz D, Keyes KM, Wall MM, Aharonovich E, Aivadyan C, Greenstein E, Spivak B, Weizman A, Frisch A, Grant BF, Hasin D: Nicotine
dependence, abuse, and craving: dimensionality in an Israeli sample. In press, Addiction.
Shmulewitz D, Keyes K, Beseler C, Aharonovich E, Aivadyan C, Spivak B, Hasin D: The dimensionality of alcohol use disorders: results from Israel. Drug Alcohol Depend 111(1-2):146-54, 2010. PDF
Beseler CL, Hasin DS: Cannabis dimensionality: dependence, abuse and consumption. Addict Behav 35(11):961-9, 2010. PDF
Hasin DS, Beseler CL: Dimensionality of lifetime alcohol abuse, dependence and binge drinking. Drug Alcohol Depend 101(1-2):53-61, 2009. PDF
Keyes KM, Hasin DS: Socio-economic status and problem alcohol use: the positive relationship between income and the DSM-IV alcohol abuse diagnosis. Addiction 103(7):1120-30, 2008. PDF
Hasin DS, Keyes KM, Alderson D, Wang S, Aharonovich E, Grant BF: Cannabis withdrawal in the United States: results from NESARC. J Clin Psychiatry 69(9):1354-63, 2008. PDF
Hasin D, Samet S, Nunes E, Meydan J, Matsoeane K, Waxman R: Diagnosis of comorbid psychiatric disorders in substance users assessed with the Psychiatric Research Interview for Substance and Mental Disorders for DSM-IV. Am J Psychiatry 163(4):689-96, 2006. PDF
Hasin DS, Hatzenbueler M, Smith S, Grant BF: Co-occurring DSM-IV drug abuse in DSM-IV drug dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend 80(1):117-23, 2005. PDF
Hasin DS, Grant BF: The co-occurrence of DSM-IV alcohol abuse in DSM-IV alcohol dependence: results of the National Epidemiologic Survey on Alcohol and Related Conditions on heterogeneity that differ by population subgroup. Arch Gen Psychiatry 61(9):891-6, 2004. PDF
Hasin D, Schuckit M, Martin CS, Grant BG, Bucholz KK, Helzer JE: The validity of DSM-IV alcohol dependence: what do we know and what do we need to know? Symposium, Research Society on Alcohol Scientific Meeting, June, 2002. Alcoholism: Clinical and Experimental Research. 27:244-252, 2003. PDF
Hasin D, Carpenter K, McCloud S, Smith M, Grant B: The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): reliability of alcohol and drug modules in a clinical sample. Drug and Alcohol Dependence 44:133-141, 1997. PDF
Hasin D, Grant B, Cottler L, Blaine J, Towle L, Ustun T, Sartorius N: Nosological comparisons of alcohol and drug diagnoses: a multisite, multi-instrument international study. Drug and Alcohol Dependence 47: 217-226, 1997. PDF
Choose another research area: Adolescent substance use
Alcohol and nicotine use disorders in Israel
Epidemiology and comorbidity of psychiatric and substance use disorders
Natural history of substance use disorders
State-level influences on drug, alcohol and psychiatric conditions
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