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Natural History of Alcohol Use Disorders |
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This work was begun in the 1980's using previously collected national data. In 1991 - 1992, a new sample of 962 community residents were interviewed who had been screened for drinking patterns that increased their risk of alcohol use disorders. One year later, subjects were re-interviewed. A ten-year follow-up has recently been completed.
Findings from this research include:
Many cases of alcohol abuse remit naturally without developing into cases of dependence.
Nearly half of the cases of DSM-IV alcohol abuse are diagnosed for one symptom: driving after drinking too much.
Withdrawal symptoms from alcohol predict chronic course of DSM-IV alcohol dependence, although tolerance to alcohol does not.
A family history of alcohol problems predicts chronicity as well as onset of DSM-IV alcohol dependence.
A heavy drinker in the household (related or unrelated) predicts chronicity of DSM-IV alcohol dependence.
Drinking to cope with negative affect predicts first-time occurrence of DSM-IV alcohol dependence after one and ten years of follow-up, but does not predict DSM-IV alcohol abuse.
Both family history of alcoholism and low level of response to alcohol predict onset of DSM-IV alcohol dependence after ten years, but not DSM-IV alcohol abuse.
Topics of current investigation in this area include investigation of the onset of alcohol dependence and likelihood of chronic heavy drinking and alcohol use disorders among subjects not in treatment. This research is supported by the National Institute on Alcohol Abuse and Alcoholism ( NIAAA ).
Selected Publications:
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Aharonovich E, Liu X, Samet S, Nunes E, Hasin D: Post-discharge cannabis use and its relationship to cocaine, alcohol and heroin use: a prospective study. In press, Am J Psychiatry. Hasin D, Hatzenbuehler M, Smith S, Grant B: Co-occurring DSM-IV Drug Abuse in DSM-IV Drug Dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions. In press, Drug Alcohol Dependence. Hasin D: Still difficult to know what alcohol dependent individuals can return to controlled drinking: comments on Dawson et al. (2005). Addiction. 2005 Mar;100(3):295-6 Hasin D, Grant BF: The co-occurrence of DSM-IV Alcohol Abuse in DSM-IV alcohol dependence: NESARC results on heterogeneity that differs by population subgroup. Arch Gen Psychiatry 61:891-896, 2004. Henderson C, Liu X, Roux A, Link B, Hasin D: The effects of US state income inequality and alcohol policies on symptoms of depression or alcohol dependence. Social Science and Medicine, 58:565-575, 2004. Goodwin RD, Hasin DS: Sedative use and misuse in the United States. Addiction 97:555-562, 2002. Hasin D, Liu X: High-risk community drinkers: a 10-year follow-up study. Abstract #103. Alcoholism Clinical and Experimental Research 27(5)(Suppl):180A. Hasin D, Paykin A, Endicott J: Course of DSM-IV alcohol dependence in a community sample: effects of parental history and binge drinking. Alcoholism: Clinical and Experimental Research 25: 411-414, 2001.PDF Hasin D, Paykin A, Meydan K, Grant B: Withdrawal and tolerance: their prognostic significance in DSM-IV alcohol dependence. Journal of Studies on Alcohol 63:431-438, 2000. Carpenter K, Hasin D: A prospective evaluation of the relationship between reasons for drinking and DSM-IV alcohol use disorders. Addictive Behaviors 23: 41-46, 1998. Hasin D, Paykin A: Dependence symptoms but no diagnosis: diagnostic "orphans" in a community sample. Drug and Alcohol Dependence 50:19-26, 1998. Hasin D, Van Rossem R, McCloud S, Endicott J: Differentiating DSM-IV alcohol dependence and abuse by course: community heavy drinkers. Journal of Substance Abuse 9:127-135, 1997. PDF Hasin D, Grant BF, Endicott J: The natural history of alcohol abuse; implications for definitions of alcohol use disorders. American Journal of Psychiatry 147:1537-1541, 1990. PDF |
Choose another research area: Genetics and epidemiology of alcohol consumption and dependence symptoms in Israel
Comorbidity of psychiatric and substance use disorders
Measurement issues in substance use and psychiatric disorders
NYSPI/Columbia University |
1051 Riverside Drive, Box 123 |
New York, New York 10032 |
Tel. (212) 543-5035 |
E-mail: dsh2@columbia.edu |