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Recent Contributions from the Leighton Group
"Tandem Asymmetric Aza-Darzens/Ring-Opening Reactions: Dual Functionality from the Silane Lewis Acid" S. Corey Valdez; Leighton, J. L. J. Am. Chem. Soc. 2009, 131, 14638-14639. [Link]
"Highly Enantioselective Pictet-Spengler Reactions with α-Ketoamide-Derived Ketimines: Access to an Unusual Class of Quaternary α-Amino Amides" Bou-Hamdan, F. R.; Leighton, J. L. Angew. Chem. Int. Ed. 2009, 48, 2403-2406. [Link]
"Tandem Silylformylation-Crotylsilylation/Tamao Oxidation of Internal Alkynes: A Remarkable Example of Generating Complexity from Simplicity" Spletstoser, J. T.; Zacuto, M. J.; Leighton, J. L. Org. Lett. 2008, 10, 5593–5596. [Link]
Department of Chemistry, Columbia University 3000 Broadway MC 3117 New York, NY 10027
Telephone: (212) 854-4262 Fax: (212) 932-1289
Email: leighton@chem.columbia.edu