Welcome to the Sims Lab at Columbia University!

Department of Systems Biology

Department of Biochemistry and Molecular Biophysics

Our group develops new tools for single cell and cell type-specific analysis, focusing mainly on proteomics and transcriptomics.  We apply cutting-edge microscopy, next-generation sequencing, and microfabrication to enable unbiased, genome-wide measurements in heterogeneous biological systems.

We are located on the 10th floor of the Irving Cancer Research Center at Columbia University Medical Center in New York City.

Latest News:

07/15/2014 - Our paper on cell type-specific gene expression in brain tumor margins is in press at PNAS.

07/07/2014 - Our paper on cell type-specific ribosome profiling and translational regulation in glioblastoma is in press at Journal of Neuroscience.

06/16/2014 - The Pe'er and Sims Labs win a RISE Award from Columbia.

05/30/2014 - Sayantan Bose wins Best Poster Award at the DSB/MAGNet Retreat.

05/12/2014 - Nick Hornstein wins a Ruth Kirschstein National Research Service Award from NIH.