Welcome to the Sims Lab at Columbia University!
Our group develops new tools for genomic analysis, focusing on applications in cancer, neuroscience, and immunology. We are located on the 2nd floor of the Lasker Biomedical Research Building at Columbia University Medical Center in New York City.
Latest News:
02/12/2025 - DEFND-seq, a scalable technique for co-sequencing RNA and DNA from individual nuclei, is now published in Nature Methods.
01/16/2025 - Our supervised machine learning framework for cell type annotation from CITE-seq and spatial profiling data is published in Cell Reports Methods. Another great collaboration with the Farber lab!
11/06/2024 - Our work on mapping immune memory to COVID-19 vaccines and influenza across human tissues with Dr. Donna Farber's lab is published in Immunity.
08/27/2024 - Our work on cell type-specific metabolic vulnerability to ferroptosis in GBM with Dr. Peter Canoll's lab is published in EMBO Journal.
