Biology
C2005/F2401 - 2009
Intro Bio
Schedule of Lectures,
recommended readings, exams, and download links
Updated
11/22/2009 05:21 PM
Students with older
editions of the texts can consult
older reading lists and find the readings for
the same topics:
++Download codes:
LH, lecture notes in html;
LP, lecture notes as pdf; M, mp3
audio of lecture; W, WMA audio of lecture;
PP, PowerPoint used in lecture; O,
outline.
To study lecture material in advance you may access those from
last year
which will be very similar.
See additional notes below.
|
Lecture: (C)hasin (M)owsh. |
Date | Subject of Lecture (last updated 11/22/2009 05:21 PM) | Recommended reading in Becker 7th ed. (B) or Savada 8th ed. (S) |
Downloads++ |
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| 1 (C) |
Tu 9/8/09 |
Introduction. Living things. Cells. Exponential growth. Water. |
B: Ch.1; Ch.2:18-31;
Ch.4:75-79 S: Ch 1 + Ch 4.1+4.2 |
LH | LP | M | W | PP |
| 2 (C) |
Th 9/10/09 |
Water contd. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. Polysaccharides. |
B: Ch.3: 46-47; 61-66 S: Ch.2; Ch 3.1, 3.3 |
LH | LP | M | W | PP |
| 3 (C) |
Tu 9/15/09 |
Polysaccharides cont. Lipids. Phospholipids. Membranes. |
B: Ch.3: 66-71; Ch7: 167-173 S: Ch. 3.4 |
LH | LP | M | W | PP |
| 4 (C) |
Th 9/17/09 |
Amino acids. Stereo-isomers. Protein structure. Peptide bonds. Small molecule separation methods. |
B: Ch.3: 41-48; Ch.2: 21-22 S: Ch 5: 96-100 |
LH | LP | M | W | PP |
| 5 (C) |
Tu 9/22/09 |
Alpha helix. Beta sheet. 3-D structure. Subunit interaction. Domains. |
B: Ch. 3: 49-54 S: Ch. 3.2 |
LH | LP | M1,2 | W1,2 | PP |
| 6 (C) |
Th 9/24/09 |
Prosthetic groups. Membrane proteins. Catalysis. Enzymes. Protein purification methods. Chemical kinetics. |
B: Ch.7:161-162,179 S: Ch. 6:125-130 |
LH | LP | M | W | PP |
| 7 (C) |
Tu 9/29/09 |
Enzyme kinetics. Enzyme inhibitors. Feedback inhibition. Free energy and the direction of chemical reactions. ATP hydrolysis. |
B: Ch. 6; Ch.5 S: Ch. 6: 130-135: 118-125 |
LH | LP | M | W | PP |
| Exam#1 |
Th 10/1/09 |
Exam #1. Covers topics actually covered in lectures 1 - 6 inclusive. Note exams are not at morning class times. Optional review session (questions answered) at the morning class time and place. |
5:40 - 7:20 PM and 7:30 - 9:10M See EXAM1 INFO page for link to room and time assignment. Email Becky Lu to request justified changes in exam room assignment |
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| 8 (C) |
Tu 10/7/09 |
Glycolysis as a pathway in intermediary metabolism. Anaerobiosis. Krebs (TCA) cycle. Electron transport. |
B: Ch.9: 224-237 S: Ch7: 138-149 |
LH | LP | M | W | PP |
| 9 (C) |
Th 10/8/09 |
Oxidative phosphorylation. Alternative energy sources. Biosynthetic pathways. |
B: Ch.10 S: Ch 7:150-157 optional glance:B:Ch.11/S:Ch.8 |
LH | LP | M | W | PP |
|
10 (M)
|
Tu 10/13/09 Drop deadline |
DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication |
B: Ch. 3:54-60 + Box 3A;Ch.
18:508-520 S: Ch. 3.5, 11.1 & 11.2 & fig. 14.6 |
LH | LP | M | W | O |
| 11 (M) |
Th 10/15/09 |
Wrap up of DNA structure; Details of DNA synthesis |
B: Ch. 19:553-566 S: Ch. 11.3 |
LH | LP | M | W | O |
| 12(M) |
Tu 10/20/09 |
PCR
|
B: Box 19A S: Ch. 11.5,
B:
Ch. 21: 645-660 &
674-end. |
LH | LP | M | W | O |
| 13 (M) |
Th 10/22/09 |
Wrap up of transcription; Intro to Translation and the genetic code. |
B: Ch. 22 to p. 692 S: Ch. 12.4 (12.5 next term) |
LH | LP | M | W | O |
| 14 (M) |
Tu 10/27/09 |
Translation & the genetic
code, cont.
Mutation (in #15) |
B: Ch. 22: 692-695 S: Ch. 12.6 |
LH | LP | M | W | O |
| Exam #2 |
Th 10/29/09 |
Exam #2. Covers topics of lectures 7 - 13. Optional review session (questions answered) at morning class time and place. |
5:40 - 7:20 PM and 7:30 - 9:10PM ** Room(s) TBA |
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|
Tu 11/03/09 |
ELECTION DAY - NO CLASS | |||||||
|
15 (M) |
Th 11/5/09 |
Regulation of protein synthesis in prokaryotes. |
B: Ch. 23 to p. 717. S: Ch. 13.4 |
LH | LP | M | W | O |
| 16 (M) |
Tu 11/10/09 |
Bacterial and viral
reproduction. |
B: Ch. 20: 620-624 & Box 18A
(p.511-512) S: Ch. 13.1-13.3 |
LH | LP | M | W | O |
| 17 (M) |
Th 11/12/09 |
Recombinant DNA technology I. Restriction enzymes & forensics. Blots and probes. |
B: Ch. 18: 521-523 &
Box 18C (530-531) S: Ch. 16.1 |
LH | LP | M | W | O |
| 18 (M) |
Tu 11/17/09 |
Recombinant DNA tech. II.
Molecular cloning;
|
B: Ch 20: 629-end. S. Ch. 16.2-end B: Ch. 21: 669-673. S: Ch. 14.2 & 14.3 |
LH | LP | M | W | O |
| 19 (M) |
Th 11/19/09 |
Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term); intro to meiosis |
B: Ch. 19: 551-553 & 572-582. S: Ch. 9.1-9.3 |
LH | LP | M | W | O |
| 20 (M) |
Tu 11/24/09 |
Eukaryotic cell division II & Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and intro to simple inheritance. |
B: Ch. 20: to p 612. S: Ch. 9.4-9.5 |
LH | LP | O | ||
|
|
Th 11/26/09 |
Thanksgiving holiday | ||||||
| 21(M) | Tu 12/01/09 | Eukaryotic Genetics I: One gene at a time. Crosses & Genetic diseases. |
B:
Ch. 20: 612-618 S: Ch. 10.1,10.2, & 10.4 pp. 225-228. (skip dihybrid crosses for now) |
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| Exam #3 |
Th 12/03/09 |
Exam #3: Covers topics of lectures 13-18. Optional review session (questions answered) at morning class time and place. |
5:40 - 7:20PM and 7:30 - 9:10M ** Room(s) TBA |
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| 22 (M) |
Tu 12/08/09 |
Crosses with more than one gene at a time. Intro to Linkage and mapping |
B:
Ch. 20: 618-620 S: Rest of Ch. 10; Ch. 17.1-17.3 & 17.5 (17.4 next term) |
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| 23 (M) |
Th 12/10/09 |
Wrap up of linkage; Darwinian evolution, population genetics and molecular evolution (last lecture) | S: Ch. 1.1 & 1.2; Ch. 22 & Ch. 24 | |||||
| Review (M) | TBA | Optional, date TBA | ||||||
| FINAL EXAM |
Tuesday, Dec. 22, 2009 4:10-7:00 |
Exam #4. EMPHASIZES LECTURES
19 - 23, but will refer back to entire course.
Important: This is not the usual date & time for a class that meets Tu-Th at 10:35. Please take this into account when buying tickets to go home. |
Rooms TBA |
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| ***Exams are designed to be completed in 75 minutes. Students with a class conflict at 5:40 exam may take the exam at 7:30 (requires permission including proof of class conflict: CU printout of schedule). Students with class conflicts at 5:40 AND 7:30 should contact Becky Lu bl2384@columbia.edu to search for an alternative. | ||||||||
| *Download codes: LH, lecture notes in html, best for viewing on a screen; LP, lecture notes as pdf, best for printing; M, audio of lecture in mp3 format; W, audio of lecture in WMA format; PP, PowerPoint, if used in lecture; O, outlines for lectures 10-end. | ||||||||
| Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. All of the 2008 lectures (on separate web page) are available for those who want to look ahead. There are links to figures in an older Purves (Savada) text embedded in the lectures. Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject. | ||||||||
| Savada and Purves refer to the same basic text: Sadava is the first author of the 8th edition, Purves was the first author of editions 1-7. | ||||||||
| Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures, the handouts, and the problems. The texts should be used to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams. You are only responsible for the links to the handouts, hard copies of which are provided in class. | ||||||||