Biology C2005/F2401 - 2008 Intro Bio
Schedule of Lectures, recommended readings, exams, and download links    Updated 09/09/2009 10:15 PM
Students with older editions of the texts can consult older reading lists and find the readings for the same topics:
++Download codes:
LH, lecture notes in html; LP, lecture notes as pdf; M, mp3 audio of lecture; W, WMA audio of lecture; PP, PowerPoint used in lecture; O, outline.
To study lecture material in advance you may access those from last year which will be very similar.  *, 2008 audio not available. Very similar 2007 version posted.  **. Truncated, missing 10 min. at end. ^ audio missing last 1 minute.
See additional notes below.

Lecture:
(C)hasin
(M)owsh.
 Date  Subject of Lecture (last updated 09/09/2009 10:15 PM) Recommended reading in Becker 7th ed. (B) or Savada 8th ed. (S) 

Downloads++
Podcast link

1 (C) Tu
9/2/08
Introduction. Living things. Cells. Exponential growth. Water. B: Ch.1; Ch.2:18-31; Ch.4:75-79
S: Ch 1 + Ch 4.1+4.2
LH LP M W PP
2 (C) Th
9/4/08
Water cont. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. Polysaccharides. B: Ch.3: 46-47; 61-66
S: Ch.2; Ch 3.1, 3.3
LH LP M* W* PP
3 (C) Tu
9/9/08
Polysaccharides cont. Lipids. Phospholipids. Membranes. B: Ch.3: 66-71; Ch7: 167-173
S: Ch. 3.4
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4 (C) Th
9/11/08
Amino acids. Stereo-isomers. Protein structure. Peptide bonds. Small molecule separation methods. B: Ch.3: 41-48; Ch.2: 21-22
S: Ch 5: 96-100
LH LP M W PP
5 (C) Tu
9/16/08
Alpha helix. Beta sheet. 3-D structure. Subunit interaction. Domains.  B: Ch. 3: 49-54
S: Ch. 3.2
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6 (C) Th
9/18/08
Prosthetic groups. Membrane proteins. Catalysis. Enzymes. Protein purification methods. Chemical kinetics. B: Ch.7:161-162,179
S: Ch. 6:125-130
LH LP M** W** PP
7 (C) Tu
9/23/08
Enzyme kinetics. Enzyme inhibitors. Feedback inhibition. Free energy and the direction of chemical reactions. ATP hydrolysis. B: Ch. 6; Ch.5
S: Ch. 6: 130-135: 118-125
LH LP M W PP
Exam#1 Th
9/25/08
Exam #1. Covers topics actually covered in lectures 1 - 6 inclusive. Note exams are not at morning class times. Optional review session (questions answered) at the morning class time and place. 5:40 - 7:20 PM and
7:30 - 9:10M ***
Room(s) TBA
         
8 (C) Th
9/30/08
Glycolysis as a pathway in intermediary metabolism.  Anaerobiosis. Krebs (TCA) cycle. Electron transport. B: Ch.9: 224-237
S: Ch7: 138-149
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9 (C) Th
10/2/08
Oxidative phosphorylation. Alternative energy sources. Biosynthetic pathways.  B: Ch.10
S: Ch 7:150-157
optional glance:B:Ch.11/S:Ch.8
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10 (M)

 

Tu   
10/7/08
Last day to drop
DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication B: Ch. 3:54-60 + Box 3A;Ch. 18:508-520
S: Ch. 3.5,
11.1 & 11.2  & fig. 14.
6
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  Th
10/9/08
No lecture. Postponed to Friday 10/10/08            
11 (M) Friday
10/10/08
 
Details of DNA synthesis and PCR

417 IAB at 10:35 AM

This lecture will not be repeated Monday evening. By request, it WILL be repeated Mon Afternoon. I apologize for any confusion.
B: Ch. 19:553-566
S:
Ch. 11.3 & 11.5
LH LP M^ W^ O
  Mon
10/13/08
Repeat of Lecture 11. 717 Hamilton, at 1:10pm.            
  Tu
10/14/08
No lecture. To compensate, there will be a lecture on Friday 10/17/08  (repeated Mon 10/27).            
12(M) Th
10/16/08
Transcription & the central dogma B: Ch. 21: 645-660 & 674-end.
S:
Ch. 12.1 -12.3
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13 (M) Friday
10/17/08
 
Translation and the genetic code.

417 IAB at 10:35 AM
Will be repeated after exam #2, on Mon 10/27/
08, 7:30-9 pm (see below)

B: Ch. 22 to p. 692
S:
Ch. 12.4 (12.5 next term)
LH LP M W O
  Tu
10/21/08
No lecture. Optional review session only. Questions answered at 5:40  class time and place. Lecture schedule will extend to include the first study day to compensate.

tRNA demo

Translation demo

         
Exam #2 Th
10/23/08
Exam #2. Covers topics of lectures 7 - 12. Optional review session (questions answered) at morning class time and place. 5:40 - 7:20 PM and
7:30 - 9:10PM **
Room(s) TBA
         
  Mon
10/27/08
Repeat of Lecture 13
Schermerhorn 614, 7:30-9pm.
           
14 (M) Tu
10/28/08
Wrap up of translation; Mutation 
 
Regulation of protein synthesis in prokaryotes.
B: Ch. 22: 692-695
S: Ch. 12.6

B: Ch. 23 to p. 717.

S:
Ch. 13.4
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15 (M)
 
Th 
10/30/08
Bacterial and viral reproduction.
We are 1/2-1 lecture behind. See outline for actual topics.
B: Ch. 20: 620-624 & Box 18A (p.511-512)
S:
Ch. 13.1-13.3
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-- Tu
11/4/08
ELECTION DAY - NO CLASS            
16 (M) Th
11/6/08
Restriction enzymes & recombinant DNA technology I. Gene cloning & forensics.  We are 1/2-1 lecture behind. See outline for actual topics. B: Ch. 18: 521-523 & Box 18C (530-531)
B: Ch 20: 629-end.
S: Ch. 16
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17 (M) Tu
11/11/08
 
Recombinant DNA tech. II. Blots and probes. Discoveries about Eukaryotic gene/genome structure. Introns and exons. We are 1/2-1 lecture behind. See outline for actual topics. (Introns next time) Same as previous lecture. Also
B: Ch. 21: 667-673.

S: Ch. 14.2 & 14.3
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18 (M) Th
11/13/08
Next time: Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term); intro to meiosis B: Ch. 19: 551-553 & 572-582.
S: Ch. 9.1-9.3
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19 (M) Tu
11/18/05
We are one lecture behind. See above.
Eukaryotic cell division II
& Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and simple inheritance.
B: Ch. 20: to p 612.
S: Ch. 9.4-9.5
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Exam #3 Th.
11/20/08
Exam #3: Covers topics of lectures 13-18.  Optional review session (questions answered) at morning class time and place. 5:40 - 7:20PM and
7:30 - 9:10M **
Room(s) TBA
         
20 (M)
 
Tu 11/25/08 Wrap up of euk. cell division (see reading for lect. 19) & then intro to
Eukaryotic genetics I: One gene at a time.
B: Ch. 20: 612-618
S: Ch. 10.1,10.2, & 10.4 pp. 225-228.
(skip dihybrid crosses for now)
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  11/27/08 Thanksgiving holiday            
 21(M) Tu  12/2/08 Euk. genetics, cont.  One Gene crosses & Genetic diseases. See readings above.
Next time: crosses with more than one gene at a time. Intro to Linkage and mapping
B: Ch. 20: 618-620
S:
Rest of Ch. 10; Ch. 17.1-17.3 & 17.5 (17.4 next term)
LH LP M W O
22 (M) Tu
12/4/08
See topic & readings for previous lecture.

 

Same as Lec. 21
 
LH LP M W O
23 (M) Tu
12/9/08
Wrap up of crossing over, linkage and mapping; then Darwinian evolution, population genetics and molecular evolution  (last lecture) Usual times & classrooms S: Ch. 1.1 & 1.2; Ch. 22 & Ch. 24 LH LP M W O
FINAL EXAM
Tuesday
Dec. 16
4-7   or
7-10
Exam #4.   EMPHASIZES LECTURES 19 - 23, but will refer back to entire course.
Important: This is not the usual date & time for a class that meets Tu-Th at 10:35. Please take this into account when buying tickets to go home.

 Rooms TBA 
         
***Exams are designed to be completed in 75 minutes. Students with a class conflict at 5:40 exam may take the exam at 7:30 (requires permission including proof of class conflict: CU printout of schedule). Students with class conflicts at 5:40 AND 7:30 should contact ________ (TBA) to search for an alternative.
*Download codes: LH, lecture notes in html, best for viewing on a screen; LP, lecture notes as pdf, best for printing; M, audio of lecture in mp3 format; W, audio of lecture in WMA format; PP, PowerPoint, if used in lecture; O, outlines for lectures 10-end.
Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. All of the 2007 lectures (on separate web page) are available for those who want to look ahead. There are links to figures in an older Purves (Savada) text embedded in the lectures.  Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject.
Savada and Purves refer to the same basic text: Sadava is the first author of the 8th edition, Purves was the first author of editions 1-7.
Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures, the handouts, and the  problems.  The texts should be used to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams.  You are only responsible for the links to the handouts, hard copies of which are provided in class).
  *, 2008 audio not available. Very similar 2007 version posted.
**. Truncated, missing 10 min. at end. See
last year's for complete lecture material