Biology C2006 / F2402 - Spring 2011 - Schedule  Last modified:   May 02, 2011

Lecture #
M = Mowsh.
F= Firestein
H = Heicklen

 Date

 Topic

Recommended reading
B = Becker, 7th ed (6th in paren. if dif. )   
S = Sadava/Purves  9th ed (8th in paren if dif.)
Sh = Sherwood, 6th ed. (5th in paren)
 

Dates for 2011 midterm exams are 2/10/10, 3/10, & 4/14. Final  5/12 (Thurs).
 Please plan carefully as there will be NO makeups. Please email Dr. M  or Jessie
<jessie@biology.columbia.edu> immediately if you foresee any difficulties with these dates.

For 2010 notes and recommended readings in older editions of the texts see   2010 schedule or Older Schedules . For recordings of 2010 see lecture links '10.
Detailed outlines for each lecture will be posted the day before (for Dr. M). Recordings of the lecture will be posted afterwards.
1  M Tu 1/18 Introduction to course; Overview of the Cell & Methods of Cell Biology
 
B: Ch.4
S: Ch.5 (4)
2 M Th 1/20
Cytoskeleton (for each euk. organelle, see appropriate part of Sa. Ch. 4.3)


Introduction to Membrane Structure (next time)
B: Ch.15 p.425-427& table 15-2, & p.446-end.
S: Ch. 5.3 (4.3)

B: Ch 7
S: Ch 6.1 & 6.2 (5.1 & 5.2)
3 M Tu 1/25 Membrane structure, Cell-cell junctions & the ECM (Junctions will be next time.) See above & B. Ch.17 p. 484- 490 (496-501)
4 M Th 1/27 Cell & tissue types

Transport of small molecules
S: Ch. 40.1 p. 835-838 (857-860)
See below.
5 M Tu 2/1 Transport of small molecules across membranes B: Ch.8
S: Ch. 6.3 & 6.4 (5.3 & 5.4)
6M Th 2/3 Moving large molecules into (& out of) the cell; RME
 
B: Ch.12 esp. p. 342-356 (338-353)
S: Ch. 6.5 (5.5)
7 M

 

Tu 2/8 Sorting of Proteins to their Proper Place (more details in 12 & 13)


Intro to Structure of Nucleus & Chromatin
  (Details of chromatin next time.)


Transport into nuclei

B: Ch.22 p.696 (702) - end
S: Ch. 14.6 (12.5)

B: Ch.18 p. 530 - 538 (533 to 541)
S: Ch. 11.3, p. 215-216 (Ch 9.3 p. 187-188)

B: Ch.18 p.538 (541) - end
S. Ch. 5.3 (4.3)

*** Thurs 2/10 Exam #1 - Covers topics in lectures 1- 6 Review Session: 10:35 am
Exam times: 5:40 and 7:30 pm
The remaining schedule is updated; references are to the 9th ed. of Sadava.
8 M Tu 2/15 Nucleoli & Chromatin Structure

Intro to Regulation of Eukaryotic Gene Activity

See above.

B: Ch. 23 p. 721- 731 (727-737)
 
9 H Th 2/17 Regulation of Eukaryotic Transcription B: Ch. 23 p. 732 -744 (737-749)
S: Ch.16.3 & 16.4 (14.4)
10 H Tu 2/22 Animal Development 1 -- Stem cells S: Ch. 19
11 H Th 2/24 Animal Development 2 -- Sex Determination See above & S: Ch. 41.3 p. 867 (889)
12 M Tu 3/1 Post Transcriptional Regulation


Role of ER in protein sorting; Roles of rest of endomembrane system (Golgi, lysosomes, etc.-- wrap up next time)
B. Ch. 23 p. 744 (750)-end.
S: Ch.16.5 (14.5 & 14.6)

B: Ch.12 & end Ch. 22
S: Ch. 5.3 & 14.6 (4.3 & 12.5)
13 M Th 3/3 How proteins get to parts of EMS (see readings for previous lecture)
Next time: how proteins get to other organelles (mitochondria, peroxisomes, etc.)
See above.
14 M  Tu 3/8 Chemical communication 1 -- signaling -- Types of signals & receptors. Intracellular receptors for lipid soluble signals; G Proteins & 2nd messengers

For Signaling overall: B. Ch. 14 & S. Ch. 7 (15); for hormones S. Ch. 41
B: Ch. 14 p. 392-406 (392-405)
S: Ch.7 (Ch.15)

S: Ch. 41, esp. 856-857 (878-879) -- receptors, & 861-863 (883-885) --thyroid

 
  *** Thurs  3/10 Review Session & Exam #2 - Covers topics in lectures 7 - 13.  See Info for Exam #2 for details. Review Session: 10:35 am
Exam times: 5:40 and 7:30 pm
  3/15, 3/17 Spring Vacation  -  no class!  
15 M Tu 3/22 Chemical communication 2 -- use of signals -- Homeostasis & Control of temperature

 

Control of Blood Glucose details (next time)

S: Ch. 40.1 & 40.4;
Sh: Ch 1 (homeostasis)
Sh: Ch. 17 p. 641-end (654-end) (temp.)

Ch. 41.3 p. 864- 865 (887) & 51.4 p. 1086 (50.4 p. 1087)
Sh: Ch. 19 p. 701-716 (719-733)

16 M Th 3/24 Chem. Commun. 3 -- Wrap up of homeostasis & Intro to Endocrinology -- (Major hormones & the HT/pituitary axis -- after electrical communication) B: Ch. 14 p. 406-419 (405-419).
S: Ch. 41
Sh: Ch. 18
17 F Tu 3/29 Electrical Communication 1  Notes are in word, not html For lect. 13 & 14, see B: Ch. 13 & S: Ch 45 (Ch 44)
18 F Th 3/31 Electrical Communication 2 Notes are in word, not html See above.
 19 M Tu 4/5 Wrap up of Electrical  Communication S: Ch. 46.1 (Ch 45.1) & figs. 47.1 & 47.10 (46.1 & 46.10)
20 M Thurs 4/7 Organization of the Nervous System & Intro to
Effectors: Skeletal & Smooth Muscle
B: Ch. 16 p. 461-473 (461-475)
S: Ch. 48.1 & 48.2 (Ch 47.1 & 47.2)
21 M Tu 4/12 Muscle contraction; heart & circulation (if time) See above & S: Ch 50.3 ( Ch 49.3)
  Thurs 4/14 Review Session & Exam #3 - Covers topics in lectures 14 -20 Review Session: 10:35 am
Exam times: 5:40 and 7:30 pm
  Tu 4/19 Jewish Holiday, no class  
22 M Th 4/21 Hormones -- Major ones

Stress response: Co-ordination of nervous & hormonal signals
See readings for lect 16 above

S: Ch. 41.3 p. 865-867 (887-888)  -- Stress
Sh: Ch. 19 p.698-701 (716-719)

23 M Tu 4/26 Kidney Function -- Salt & Water Homeostasis


Intro to immune response next time

S: Ch. 52.4 -52.6 (Ch 51.4-51.6)

S: Ch. 42 ( Ch 18).

24 M  Th 4/28 Molec. & Cell. details of Immune Response
PM lecture starts at 6:10.

If you want to read ahead, see Lect 23 & 24 of '09

S: Ch. 42 (Ch 18).
25 M Tu 5/3 Optional Additional Lecture: Regulation of the Cell Cycle & Cancer. Usual times & places.
 
B:  19 p. 582 -end (586-end) & Ch. 24
S: Ch. 11.2 (Ch 9.2) & Ch. 11.7 (Ch 17.4)
    5/3 to 5/5  Study Days. Optional Review before final TBA (prob. after study days)  
   Thurs 5/12 Exam #4 - EMPHASIZES LECTURES 21 - 24, but may refer back to the entire course. Exam will be at 4:10; later session for conflicts if needed. 6 pm for those in Sames' Orgo class.
Sherwood's Physiology  is completely optional, for those who like to read in more depth. See Textbooks for more details.