Biology W 3031/4031 Genetics

Spring 2002

Review Sessions for Final Exam.

Thurs May 9 and Sun May 11 at 8:10 PM in Rm 800 Fairchild

Instructors:  James W. Erickson
614 A Fairchild
Office Hours: Wednesday 2:00-4:00 (or by appointment)

Scott Kachlany
Hammer Bldg HHSC 15th Floor Rm 1518
Office Hours: by appointment.

Lectures: T & Th. 6:10-7:25 -310 Fayerweather

Teaching Assistants:  There are no TAs for this course

There are no recitation sections. There will be pre-exam review sessions

Text book:

ìGenetics the Continuity of Lifeî, D.J. Fairbanks and W.R. Anderson.  1999.  Brooks/Cole. Student Companion, D.J. Fairbanks and W.R. Anderson.
Alternate Texts:
These excellent texts are a little more advanced than Fairbanks.  Both were recommended last semester and should be available new or used from the bookstore.  If you want to use one of these in place of Fairbanks thatís fine, but you will be responsible for figuring out which text chapters correspond to the lectures as they are presented in a very different order.  All three texts include excellent example problems.

"An Introduction to Genetic Analysis", 7th edition, A.J.F. Griffiths, J.H. Miller, D.T. Suzuki, R.C. Lewontin, and W.M. Gelbart.  2000, Freeman. And Solutions Manual, W. Fixsen.

"Genetics:  From Genes to Genomesî L.H. Hartwell, L. Hood, M.L. Goldberg, A.E. Reynolds, L.M. Silver, R.C. Veres. 2000, McGraw-Hill Higher Education.

Supplemental Texts:  It is often helpful to see how other authors cover similar material.  The following books or materials are on reserve in the Biology Library 6th floor Fairchild.

Basic Genetics texts/CDs:

"Principles of Genetics", 2nd edition. D.P. Snustad, M.J. Simmons. 1999.  "Study Guide and Problems Workbook" for Principles of Genetics 2nd edition,  H.J. Price, 1999.  I used Snustad as the course text in 1999/2000.  It's a good book and some students have found it clearer than Griffiths.

"Genetics", R.J. Brooker. 1st Edition 1998, Benjamin Cummings.  Another excellent Genetics text.

Advanced or Specialized texts: Growth of the Bacterial Cell.  J.L. Ingraham, O. Maaløe, F.C. Neidhardt.  An old text but it is a wonderful source of information on bacterial physiology with a useful primer on bacterial genetics.  Also, Physiology of the Bacterial Cell. F.C. Neidhardt, J.L. Ingraham, M Schaechter.  A newer verision of GBC.

Microbial Genetics.  2nd ed.  S. Maloy et al.  Very good on bacterial and phage techniques and on bacterial gene expression.
A Genetic Switch.  2nd ed.  M. Ptashne.  Very clear treatment of phage and bacterial gene expression.  Good intro to gene expression and on the logic of molecular genetic analysis.  This is an excellent book.

The lac operon. B. Müller-Hill (1996). A short history of a Genetic Paradigm.

The Eighth Day of Creation.  H. F. Judson (1979) An historical account of the dawn of molecular biology.  Very good and readable popular history of DNA structure, Genetic code, lac operon, and protein structure.  Includes the experiments and the personalities.

Molecular Cell Biolog.   H. Lodish et al.  A comprehensive advanced text.  If you want more details on DNA/RNA structure function, recombinant DNA methods, gene expression and developmental genetics look here.  Also try, Genes VII or VIII.  B. Lewin.

Developmental Biology.  6th ed.  S. Gilbert.  More advanced than Griffiths, but is useful topics in developmental gene regulation and cancer/disease genetics.

Exams, Homework, and Grades:
There will be two midterm exams and a final.  The final exam will be cumulative.  Your course grade will be determined by the exams (midterms 60%, final 40%).
Problems from the Text and old exam problems:
One of the best ways to learn Genetics is to solve problems on the material.  You should do ALL the relevant problems from the chapters.  The Student Companion contains complete solutions for the problems in the text.  In addition, a series of short problems and solutions (mostly past exam problems) are posted on the internet.   Be sure to do the problems in the text and especially from the web and donít fall too far behind.  You are unlikely to do well in this course if you donít do the problems or put them off until the last minute.

Course Schedule Spring 2002

Supplemental Material:

Lecture 1,2: websites | handouts and overheads 2001 material

Lecture 1,2: websites | handouts and overheads 2001 material

Lecture 7: websites | handouts 2002 material

Lecture 8: websites | handouts 2002 material

Lecture 9: websites | handouts 2002 material

Lecture 10: websites | handouts 2002 material

Lecture 11: websites | handouts 2002 material

Lecture 12: websites | handouts 2002 material


Additional Problems: Lectures 1-2 2002 material Answers to problems for Lectures 1-2  2002 material Lectures 5-7 2002 material. Answers to problems for Lectures 5-7 2002 material. Lectures 8-10 2002 material Answers to problems for Lectures 8-10 2002 material

Email questions from students with answers:

Questions and Answers Related to first exam

Previous year's exams.

Note the course structure has changed in 2002.  Some
old exam 2 material will now be included on 2002 exam 1.

2000 Exams:

Exam 1 Questions only
Exam 1 Questions & Answers
Exam 2 Questions only
Exam 2 Questions & Answers
Exam 3 Questions only
Exam 3 Questions & Answers
2001 Exams: Exam 1 Questions & Answers Exam 2 Questions & Answers Exam 3 Questions & Answers
2002 Exams: Exam 1 Questions & Answers
Exam 1  Grade Distribution

Exam 2 Questions & Answers
Exam 2  Grade Distribution