Spring 2002
Review Sessions for Final Exam.
Thurs May 9 and Sun May 11 at 8:10 PM in Rm 800 Fairchild
Instructors: James W. Erickson
614 A Fairchild
jwe7@columbia.edu
854-4625
Office Hours: Wednesday 2:00-4:00 (or by appointment)
Scott Kachlany
Hammer Bldg HHSC 15th Floor Rm 1518
sk564@columbia.edu
305-1483
Office Hours: by appointment.
Lectures: T & Th. 6:10-7:25 -310 Fayerweather
Teaching Assistants: There are no TAs for this course
There are no recitation sections. There will be pre-exam review sessions
Text book:
ìGenetics the Continuity of Lifeî, D.J. Fairbanks and W.R. Anderson. 1999. Brooks/Cole. Student Companion, D.J. Fairbanks and W.R. Anderson.Alternate Texts:
These excellent texts are a little more advanced than Fairbanks. Both were recommended last semester and should be available new or used from the bookstore. If you want to use one of these in place of Fairbanks thatís fine, but you will be responsible for figuring out which text chapters correspond to the lectures as they are presented in a very different order. All three texts include excellent example problems.Supplemental Texts: It is often helpful to see how other authors cover similar material. The following books or materials are on reserve in the Biology Library 6th floor Fairchild."An Introduction to Genetic Analysis", 7th edition, A.J.F. Griffiths, J.H. Miller, D.T. Suzuki, R.C. Lewontin, and W.M. Gelbart. 2000, Freeman. And Solutions Manual, W. Fixsen.
"Genetics: From Genes to Genomesî L.H. Hartwell, L. Hood, M.L. Goldberg, A.E. Reynolds, L.M. Silver, R.C. Veres. 2000, McGraw-Hill Higher Education.
Basic Genetics texts/CDs:
"Genetics", R.J. Brooker. 1st Edition 1998, Benjamin Cummings. Another excellent Genetics text.
Microbial Genetics. 2nd ed. S. Maloy et al.
Very good on bacterial and phage techniques and on bacterial gene expression.
A Genetic Switch. 2nd ed. M. Ptashne. Very clear
treatment of phage and bacterial gene expression. Good intro to gene
expression and on the logic of molecular genetic analysis. This is
an excellent book.
The lac operon. B. Müller-Hill (1996). A short history of a Genetic Paradigm.
The Eighth Day of Creation. H. F. Judson (1979) An historical account of the dawn of molecular biology. Very good and readable popular history of DNA structure, Genetic code, lac operon, and protein structure. Includes the experiments and the personalities.
Molecular Cell Biolog. H. Lodish et al. A comprehensive advanced text. If you want more details on DNA/RNA structure function, recombinant DNA methods, gene expression and developmental genetics look here. Also try, Genes VII or VIII. B. Lewin.
Developmental Biology. 6th ed. S. Gilbert. More advanced than Griffiths, but is useful topics in developmental gene regulation and cancer/disease genetics.
There will be two midterm exams and a final. The final exam will be cumulative. Your course grade will be determined by the exams (midterms 60%, final 40%).Problems from the Text and old exam problems:
One of the best ways to learn Genetics is to solve problems on the material. You should do ALL the relevant problems from the chapters. The Student Companion contains complete solutions for the problems in the text. In addition, a series of short problems and solutions (mostly past exam problems) are posted on the internet. Be sure to do the problems in the text and especially from the web and donít fall too far behind. You are unlikely to do well in this course if you donít do the problems or put them off until the last minute.
Supplemental Material:
Lecture 1,2: websites | handouts and overheads 2001 material
Lecture 7: websites | handouts 2002 material
Lecture 8: websites | handouts 2002 material
Lecture 9: websites | handouts 2002 material
Lecture 10: websites | handouts 2002 material
Lecture 11: websites | handouts 2002 material
Lecture 12: websites | handouts 2002 material
Lecture:
Email questions from students with answers:
Previous year's exams.
Note the course structure has changed in 2002. Some
old exam 2 material will now be included on 2002 exam 1.
2000 Exams:
