Last updated: 08/07/11 06:24 PM



Corrections

Biology C2005 and F2401: Intro Bio

HANDOUTS (click on handout name to download)
Lec.: 1 . 2 . 3 . 4 . 5 . 6 . 7 . 8 . 9 . 10 . 11 .12 . 13 . 14 . 15 . 16 . 17 . 18 . 19 . 20 . 21 . 22 . 23
Lec. 1 1-1 Functional groups
  1-2 Exponential growth
  1-3 Flow of glucose through metabolic pathways
Lec. 2 2-1 Polarity I  
  2-2 Polarity II
  2-3 Important polymers summary
  2-4 Linkages in polymers
  2-5 Minimal medium for E. coli; Bond strengths; Macromolecules
  2-6 Carbohydrates
  2-7 Glucose ring formation
  2-8 Glucose chair views; disaccharides as chairs
  2-9 Lipids
Lec. 3 3-1 Amino acids and peptides
  3-2 Amino acids (all 20)
  3-3 Polypeptides
  3-4 Paper chromatography
Lec. 4 4-1 Protein structure: 4 levels
  4-2 Protein structure: domains, space-filling and ribbon models. 
  4-3 Protein separation methods
Lec. 5    
Lec. 6 5-1 Derivation of the Michaelis-Menten equation
(numbered 5-x) 5-2a-d Enzyme kinetics mechanism, Michaelis-Menten graph, Competitive and non-competitive inhibition graphs
  5-3a-c Allopurinol--A competitive inhibitor example; competitive and non-competitive inhibition schemes
  5-4 Enzyme inhibition summary
Lec. 7 7-1a,b; 7-3; 7-4a,b,c Regeneration of ATP and NAD, NAD structure, 1st 5 steps, oxidation of gkyceradehyde-3-PO4, energy levels in glycolysis
  7-2 Glycolytic pathway
Lec. 8 8-1 Krebs Cycle
  8-2; 8-5a,b Electron transport energy levels, ATP synthetase structure and mechanism
  8-3 Electron transport chain
  8-4 Mitochondria and the electron transport chain in the membrane
  8-6 Outline of energy metabolism
Lec. 9 9-1, 9-3 Fatty acid and triglyceride metabolism
  9-2 Transamination and deamination; serine biosynthesis
9-4 Hyaluronic acid biosynthesis (a polysaccharide)
9-5 You are what you eat?
     
    Dr. Mowshowitz's  handouts will be posted here online after each lecture.
Handouts are provided in class because they are intended to be used on the spot. Extra paper copies of all handouts will be placed in the cubby boxes on the 7the floor of Mudd, outside Dr. M's office, after the evening lecture.  Scanned copies of the handouts will be posted here after each lecture. (Links to most handouts are in each individual lecture.)
Lec. 10 10-1 Structure of Nucleotides (pdf)
  10-2 Shorthand
  10-3 Base Pairing, Structure of Chain, etc.
  10-4 Bases & Tautomers
Lec. 11 11-1 11-1 -- Meselson-Stahl Experiment (pdf)
  11-2  11-2 -- Synthesis of DNA -- Where the Energy Comes From (html)
  11-3  11-3 -- DNA Replication - Details at Fork (pdf)
Lec. 12 12-A 12-A -- PCR
  12-B 12-B = Comparison of RNA & DNA synthesis
Articles from NY Times -- not on web -- on back of 12A.
Lec. 13 13-A 13A -- code table & tRNA structure
  13-B 13B -- Protein Synthesis
     
Lec. 14 14-A 14A -- Wobble & Ribosome Structure
14-B 14B -- tRNA Loading
     
Lec. 15 15-A 15A -- Induction & Feedback Inhibition vs Repression
  15-B 15B -- Operons
     
Lec.  16 16-A 16A -- Plasmid vs Fragment & Integration of Fragment
  16-B 16B -- Complementation
     
Lec. 17 17-A 17A -- Viral Life Cycle
  17-B 17B -- Restriction enzymes & Overview of Making a Chimeric Plasmid
  17-C 17C -- Blots
  17-D 17D -- Examples of Restriction Enzymes, & RFLPs
   
Lec. 18 18-A 18A -- A Cloning Vehicle
  18-B 18B -- How to make a library
  18-C 18C = Introns & Splicing 
     
Lec. 19 19A 19A  = Meiosis/Mitosis    
  19B 19B = Chromosome squashes, karyotypes & chromosome structure
Lec. 20 20A 20A = Meiotic Chromosome Cycle 
  20B 20B = Super Cycle & Nondisjunction
     
Lec. 21 21A 21A -- Monohybrid Crosses
  21B 21B -- Pedigrees
     
Lec. 22 22A 22A -- Dihybrid Crosses
  22B 22B -- Independent Assortment & Linkage
     
Lec. 23 23A 23A -- Crossing Over & Recombination Frequency
  23B 23B --  Hardy Weinberg Law
  23C 23C = How to measure RF's in diploids. This handout is on the web only-- no paper copies.
  Reminder!! Handouts not on web (and extra copies of all handouts) are in boxes on 7th Floor Mudd outside 744.