Selected Online Publications


Single copies of the articles can be downloaded and printed for the reader's personal research and studied for informational purposes only.


Brenner DJ. Breast Cancer Management interview. Breast Cancer Management.. (2014) 3(4), 315-319. [PDF]

Fazel R, Gerber TC, Balter S, Brenner DJ, Carr JJ, Cerqueira MD, Chen J, Einstein AJ, Krumholz HM, Mahesh M, McCollough CH, Min JK, Morin RL, Nallamothu BK, Nasir K, Redberg RF, Shaw LJ. Approaches to enhancing radiation safety in cardiovascular imaging: a scientific statement from the american heart association. Circulation. 2014 Nov 4. [PDF]

Xu Y, Zhang B, Messerli M, Randers-Pehrson G, Hei TK, Brenner DJ. Metabolic oxygen consumption measurement with a single-cell biosensor after particle microbeam irradiation. Mutagenesis. 2014 Sep 13. [Epub ahead of print] [abstract]

Balajee AS, Bertucci A, Taveras M, Brenner DJ. Multicolour FISH analysis of ionising radiation induced micronucleus formation in human lymphocytes. Radiat Environ Biophys.. 2014 Oct 22. [Epub ahead of print] [abstract]

Goudarzi M, Mak TD, Chen C, Smilenov LB, Brenner DJ, Fornace AJ. The effect of low dose rate on metabolomic response to radiation in mice. Radiat Environ Biophys. 2014 Jul 22. [abstract] [PDF]

Brown JM, Carlson DJ, Brenner DJ. Dose escalation, not “new biology,” can account for the efficacy of stereotactic body radiation therapy with non-small cell lung cancer. In reply to Rao et al. Int J Radiat Oncol Biol Phys. 2014 Jul 1;89(3):693-4. [abstract] [PDF]

Repin M, Turner HC, Garty G, Brenner DJ. Next generation platforms for high-throughput biodosimetry. Radiat Prot Dosimetry. 2014 Jun;159(1-4):105-10. [abstract] [PDF]

Shuryak I, Lubin JH, Brenner DJ. Potential for adult-based epidemiological studies to characterize overall cancer risks associated with a lifetime of CT scans. Radiat Res. 2014 Jun;181(6):584-91. [abstract] [PDF]

Halm BM, Franke AA, Lai JF, Turner HC, Brenner DJ, Zohrabian VM, Dimauro R. γ-H2AX foci are increased in lymphocytes in vivo in young children 1 h after very low-dose X-irradiation: a pilot study. Pediatr Radiol. 2014 Apr 23.[abstract] [PDF]

Laiakis EC, Mak TD, Anizan S, Amundson SA, Barker CA, Wolden SL, Brenner DJ, Fornace AJ Jr.
Development of a Metabolomic Radiation Signature in Urine from Patients Undergoing Total Body Irradiation. Radiat Res. 2014 Mar 27. [abstract] [PDF]

Lyulko OV, Garty G, Randers-Pehrson G, Turner HC, Szolc B, Brenner DJ. Fast Image Analysis for the Micronucleus Assay in a Fully Automated High-Throughput Biodosimetry System. Radiat Res. 2014 Feb 6. [abstract] [PDF]

Turner HC, Sharma P, Perrier JR, Bertucci A, Smilenov L, Johnson G, Taveras M, Brenner DJ, Garty G. The RABiT: high-throughput technology for assessing global DSB repair. Radiat Environ Biophys. 2014 Jan 30. [abstract] [PDF]

Brown JM, Carlson DJ, Brenner DJ. The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved? Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):254-62. [abstract] [PDF]

Grad M, Young EF, Smilenov L, Brenner DJ, Attinger D. A simple add-on microfluidic appliance for accurately sorting small populations of cells with high fidelity. J Micromech Microeng. 2013;23(11). [abstract] [PDF]

Goudarzi M, Weber W, Mak TD, Chung J, Doyle-Eisele M, Melo D, Brenner DJ, Guilmette RA, Fornace AJ. Development of urinary biomarkers for internal exposure by cesium-137 using a metabolomics approach in mice. Radiat Res. 2014 Jan;181(1):54-64. [abstract] [PDF]

Shuryak I, Smilenov LB, Kleiman NJ, Brenner DJ. Potential reduction of contralateral second breast-cancer risks by prophylactic mammary irradiation: validation in a breast-cancer-prone mouse model. PLoS One. 2013 Dec 20;8(12):e85795. [abstract] [PDF]

Brenner DJ, Vazquez M, Buonanno M, Amundson SA, Bigelow AW, Garty G, Harken AD, Hei TK, Marino SA, Ponnaiya B, Randers-Pehrson G, Xu Y. Integrated interdisciplinary training in the radiological sciences. Br J Radiol. 2014 Feb;87(1034):20130779. [abstract] [PDF]

Brenner DJ. What we know and what we don't know about cancer risks associated with radiation doses from radiological imaging. Br J Radiol. 2014 Jan 20. [abstract] [PDF]

Brenner DJ, Shuryak I, Jozsef G, Dewyngaert KJ, Formenti SC. Risk and risk reduction of major coronary events associated with contemporary breast radiotherapy. JAMA Intern Med. 2014 Jan;174(1):158-60. [PDF]

Buonanno M, Randers-Pehrson G, Bigelow AW, Trivedi S, Lowy FD, Spotnitz HM, Hammer SM, Brenner DJ. 207-nm UV light - a promising tool for safe low-cost reduction of surgical site infections. I: in vitro studies. PLoS One. 2013 Oct 16;8(10):e76968. [abstract] [PDF]

Grad M, Harken A, Randers-Pehrson G, Attinger D, Brenner DJ. An ultra-thin Schottky diode as a transmission particle detector for biological microbeams. J Instrum. 2012 Dec;7. pii: P12001. [abstract] [PDF]

Ponnaiya B, Amundson SA, Ghandhi SA, Smilenov LB, Geard CR, Buonanno M, Brenner DJ. Single-cell responses to ionizing radiation. Radiat Environ Biophys. 2013 Nov;52(4):523-30. [abstract] [PDF]

Buonanno M, Garty G, Grad M, Gendrel M, Hobert O, Brenner DJ. Microbeam irradiation of C. elegans nematode in microfluidic channels. Radiat Environ Biophys. 2013 Nov;52(4):531-7. [abstract] [PDF]

Schissler AJ, Rozenshtein A, Kulon ME, Pearson GD, Green RA, Stetson PD, Brenner DJ, D'Souza B, Tsai WY, Schluger NW, Einstein AJ. CT pulmonary angiography: increasingly diagnosing less severe pulmonary emboli. PLoS One. 2013 Jun 12;8(6):e65669. [abstract] [PDF]

Lyulko OV, Randers-Pehrson G, Brenner DJ. Simultaneous immersion Mirau interferometry. Rev Sci Instrum. 2013 May;84(5):053701. [abstract] [PDF]

Bigelow AW, Ponnaiya B, Targoff KL, Brenner DJ. UV microspot irradiator at Columbia University. Radiat Environ Biophys. 2013 Aug;52(3):411-7. Epub 2013 May 26. [abstract] [PDF]

Manuela Buonanno, Gerhard Randers-Pehrson, Alan W. Bigelow, Sheetal Trivedi, Franklin D. Lowy, Henry M. Spotnitz, Scott M. Hammer, David J. Brenner. 207-nm UV Light - A Promising Tool for Safe Low-Cost Reduction of Surgical Site Infections. I: In Vitro Studies. Plos One, Vol. 8 Iss. 10. Oct 2013. [PDF]

Brown JM, Brenner DJ, Carlson DJ. Dose escalation, not "new biology," can account for the efficacy of stereotactic body radiation therapy with non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2013 Apr 1;85(5):1159-60. [abstract] [PDF]

Xu Y, Turner HC, Garty G, Brenner DJ. A Rapid, Quantitative Method to Characterize The Human Lymphocyte Concentration for Automated High-Throughput Radiation Biodosimetry. Biomed. Eng. Res. Vol. 2 Iss. 1 PP. 16-19, March (2013). [PDF]

Grad, M., Bigelow, A.W., Garty, G., Attinger, D. and Brenner D.J. Optofluidic cell manipulation for a biological microbeam. Rev. Sci. Instrum. 84: 014301 (2013), PMCID: PMC3562345. [abstract] [PDF]

*Brenner DJ. Radiation and chest CT scans: are there problems? What should we do? Chest 142:549-50 (2012) [abstract] [PDF]

*Brenner DJ. Minimizing medically unwarranted computed tomography scans. Ann ICRP. 41:161-9 (2012).[abstract] [PDF]

*Brenner DJ. We can do better than effective dose for estimating or comparing low-dose radiation risks. Ann ICRP. 41:124-8 (2012). [abstract] [PDF]

*Brenner DJ, Hall EJ. Cancer Risks from CT Scans: Now We Have Data, What Next? Radiology. 265:330-1 (2012). [abstract] [PDF]

*Brenner DJ. Exploring two two-edged swords. Radiat Res. 178:7-16 (2012). [abstract] [PDF]

Shuryak I, Brenner DJ. Mechanistic analysis of the contributions of DNA and protein damage to radiation-induced cell death. Radiat Res. 178:17-24 (2012). [abstract] [PDF]

Becker SJ, Elliston CD, Dewyngaert K, Jozsef G, Brenner DJ, Formenti S. Breast radiotherapy in the prone position primarily reduces the maximum out-of-field measured dose to the ipsilateral lung. Med Phys. 39:2417-23 (2012). [abstract] [PDF]

Chen Y, Wang H, Zhang J, Garty G, Simaan N, Yao YL, Brenner DJ. Automated recognition of robotic manipulation failures in high-throughput biodosimetry Tool. Expert Syst Appl. 39:9602-11 (2012). [abstract] [PDF]

Milne EN, Brenner DJ, Shuryak I, Einstein AJ. The older, the better. Radiology. 263(1):306-7 (2012). [abstract] [PDF]

Brenner DJ, Sachs RK, Peters LJ, Withers HR, Hall EJ. We forget at our peril the lessons built into the α/β model. Int J Radiat Oncol Biol Phys. 82(4):1312-4 (2012). [abstract] [PDF]

Ng J, Shuryak I, Xu Y, Clifford Chao KS, Brenner DJ, Burri RJ. Predicting the Risk of Secondary Lung Malignancies Associated with Whole-Breast Radiation Therapy. Int J Radiat Oncol Biol Phys. Epub: Jan 13 (2012). [abstract] [PDF]

Einstein AJ, Elliston CD, Groves DW, Cheng B, Wolff SD, Pearson GD, Robert Peters M, Johnson LL, Bokhari S, Johnson GW, Bhatia K, Pozniakoff T, Brenner DJ. Effect of bismuth breast shielding on radiation dose and image quality in coronary CT angiography. J Nucl Cardiol. 19:100-8 (2012). [abstract] [PDF]

Shuryak, I., Brenner, D.J. and Ullrich, R.L. Radiation-induced carcinogenesis: mechanistically based differences between gamma-rays and neutrons, and interactions with DMBA. PLoS One. 6: 1-8. e28559 (2011), PMCID: PMC3237439. [abstract] [PDF]

David J. Brenner, PhD, DSc, Igor Shuryak, MD, PhD and Andrew J. Einstein, MD, PhD. Impact of Reduced Patient Life Expectancy on Potential Cancer Risks from Radiologic Imaging. Radiology. October 1, 2011. [abstract] [PDF]

Harken AD, Randers-Pehrson G, Johnson GW, Brenner DJ. The Columbia University proton-induced soft x-ray microbeam. Nucl Instrum Methods Phys Res B. 2011 Sep 15;269(18):1992-1996. [abstract] [PDF]

Shuryak I, Hahnfeldt P, Hlatky L, Sachs RK, Brenner DJ. Erratum to: A new view of radiation-induced cancer: integrating short- and long-term processes. Parts I and II. Radiat Environ Biophys. 2011 Aug 24. [abstract] [PDF]

Williams JP, Huser AK, Brenner DJ. Introduction. Int J Radiat Biol. 2011 Aug;87(8):747. [abstract] [PDF]

Garty G, Karam A, Brenner DJ. Infrastructure to support ultra high throughput biodosimetry screening after a radiological event. Int J Radiat Biol. 2011 Aug;87(8):754-65. Epub 2011 Jun 15. [abstract] [PDF]

Garty G, Chen Y, Turner HC, Zhang J, Lyulko OV, Bertucci A, Xu Y, Wang H, Simaan N, Randers-Pehrson G, Lawrence Yao Y, Brenner DJ. The RABiT: A Rapid Automated Biodosimetry Tool for radiological triage. II. Technological developments. Int J Radiat Biol. 2011 Aug;87(8):776-90. Epub 2011 May 11. [abstract] [PDF]

Brenner DJ, Shuryak I, Einstein AJ. Impact of Reduced Patient Life Expectancy on Potential Cancer Risks from Radiologic Imaging. Radiology. 2011 Jul 19. [abstract] [View online]

Barcellos-Hoff M.H., Brenner D.J., Brooks A.L., Formenti S., Hlatky L., Locke P.A., Shore R., Tenforde T., Travis E.L. and Williams J. Low-dose radiation knowledge worth the cost. Science 332:305-306 (2011). [abstract] [PDF]

Brenner D.J. We don't know enough about low-dose radiation risk. NatureNews Published online Apr. 5, 2011. [view online]

Brenner D.J. Are x-ray backscatter scanners safe for airport passenger screening? For most individuals, probably yes, but a billion scans per year raises long-term public health concerns. Radiology 259:6-10 (2011). [abstract] [PDF]

Chen C., Brenner D.J., Brown T.R. Identification of urinary biomarkers from x-irradiated mice using NMR spectroscopy. Radiat. Res. Epub ahead of print Feb. 21 (2011). [abstract] [PDF]

Templin T. Amundson S.A., Brenner D.J. and Smilenov L.B. Whole mouse blood microRNA as biomarkers for exposure to γ-rays and 56Fe ion. Int. J. Radiat. Biol. Epub ahead of print Jan. 28 (2011). [abstract] [PDF]

Turner H.C., Brenner D.J., Chen Y., Bertucci A., Zhang J., Wang H., Lyulko O.V., Xu Y., Shuryak I., Schaefer J., Simaan N., Randers-Pehrson G., Yao Y.L., Amundson S.A. and Garty G. Adapting the γ-H2AX Assay for Automated Processing in Human Lymphocytes. 1. Technological Aspects. Radiat. Res. 175:282-290 (2011). [abstract] [PDF]

Hricak H., Brenner D.J., Adelstein S.J., Frush D.P., Hall E.J., Howell R.W., McCollough C.H., Mettler F.A., Pearce M.S., Suleiman O.H., Thrall J.H. and Wagner L.K. Managing radiation use in medical imaging: A multifaceted challenge. Radiology 258:889-905 (2011). [abstract] [PDF]

Garty G., Grad M., Jones B.K., Xu Y., Xu J., Randers-Pehrson G., Attinger D. and Brenner DJ. Design of a novel flow-and-shoot microbeam. Radiat. Prot. Dosimetry 143:344-348 (2011). [abstract] [PDF]

Xu Y., Randers-Pehrson G., Marino S.A., Bigelow A.W., Akselrod M.S., Sykora J.G. and Brenner D.J. An accelerator-based neutron microbeam system for studies of radiation effects. Radiat. Prot. Dosimetry epub ahead of print Dec. 3 (2010). [abstract] [PDF]

Shuryak I., Sachs R.K. and Brenner D.J. A new view of radiation-induced cancer. Radiat. Prot. Dosimetry 143:358-364 (2010). [abstract] [PDF]

Shuryak I., Sachs R.K. and Brenner D.J. Cancer risks after radiation exposure in middle age. J. Natl. Cancer Inst. 102:1628-1636 (2010). [abstract] [PDF]

Brenner D.J. Slowing the increase in the population dose resulting from CT scans. Radiat. Res. 174:809-815 (2010). [abstract] [PDF]

Shuryak I., Ullrich R.L., Sachs R.K. and Brenner D.J. The Balance Between Initiation and Promotion in Radiation-Induced Murine Carcinogenesis. Radiat. Res. 174:357-366 (2010). [abstract] [PDF]

Kovalchuk O., Zemp F.J., Filkowski J., Altamirano A., Dickey J.S., Jenkins-Baker G., Marino S.A., Brenner D.J., Bonner W.M. and Sedelnikova O.A. microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways. Carcinogenesis 31:1882-1888 (2010). [abstract] [PDF]

Brenner D.J. and Hricak H. Radiation exposure from medical imaging: Time to regulate? JAMA 304:208-209 (2010). [abstract] [PDF]

Shuryak I. and Brenner D.J. Effects of radiation quality on interactions between oxidative stress, protein and DNA damage in Deinococcus radiodurans. Radiat. Environ. Biophys. 49:693-703 (2010). [abstract] [PDF]

Brenner D.J. Should we be concerned about the rapid increase in CT usage? Rev. Environ. Health 25:63-68 (2010). [abstract] [PDF]

Schettino G., Johnson G.W., Marino S.A. and Brenner D.J. Development of a method for assessing non-targeted radiation damage in an artificial 3D human skin model. Int. J. Radiat. Biol. 86:593-601 (2010). [abstract] [PDF]

Coy S.L., Krylov E.V., Schneider B.B., Covey T.R., Brenner D.J., Tyburski J.B. Patterson A.D., Krausz K.W., Fornace A.J. and Nazarov E.G. Detection of radiation-exposure biomarkers by differential mobility prefiltered mass spectrometry (DMS-MS). Int. J. Mass Spectrom. 291:108-117 (2010).[abstract] [PDF]

Brenner D.J. Contralateral second breast cancers: prediction and prevention. J. Natl. Cancer Inst. 102:444-445 (2010). [abstract] [PDF]

Brenner D.J. Medical imaging in the 21st century - Getting the best bang for the rad. N. Engl. J. Med. 362:943-945 (2010). [abstract] [PDF]

Einstein A.J., Elliston C.D., Arai A.E., Chen M.Y., Mather R., Pearson G.D., Delapaz R.L., Nickoloff E., Dutta A. and Brenner D.J. Radiation dose from single-heartbeat coronary CT angiography performed with a 320-detector row volume scanner. Radiology 254:698-706 (2010). [abstract] [PDF]

Randers-Pehrson G., Johnson G.W., Marino S.A., Xu Y., Dymnikov A.D. and Brenner D.J. The Columbia University sub-micron charged particle beam. Nucl. Instrum. Methods Phys. Res. A. 609:294-299 (2009). [abstract] [PDF]

Garty G., Chen Y., Salerno A., Turner H., Zhang J., Lyulko O., Bertucci A., Xu Y., Wang H., Simaan N., Randers-Pehrson G., Yao Y.L., Amundson S.A. and Brenner D.J. The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys. 98:209-17 (2010). [abstract] [PDF]

Brenner D.J. Extrapolating radiation-induced cancer risks from low doses to very low doses. Health Phys. 97:505-509 (2009). [abstract] [PDF]

Kirkpatrick J.P., Brenner D.J. and Orton C.G. Point/Counterpoint. The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery. Med. Phys. 36:3381-3384 (2009). [abstract] [PDF]

Brenner D.J., Elliston C.D., Hall E.J. and Paganetti H. Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator. Phys. Med. Biol. 54:6065-6078 (2009). [abstract] [PDF]

Shuryak I. and Brenner D.J. A model of interactions between radiation-induced oxidative stress, protein and DNA damage in Deinococcus radiodurans. J. Theor. Biol. 261:305-317 (2009). [abstract] [PDF]

Shuryak I., Hahnfeldt P., Hlatky L., Sachs R.K. and Brenner D.J. A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: Approach. Radiat. Environ. Biophys. 48:263-274 (2009). [abstract] [PDF]

Shuryak I., Hahnfeldt P., Hlatky L., Sachs R.K. and Brenner D.J. A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. Radiat. Environ. Biophys. 48:275-286 (2009). [abstract] [PDF]

Bigelow A.W., Garty G., Funayama T., Randers-Pehrson G., Brenner D.J. and Geard C. Expanding the question-answering potential of single-cell microbeams at RARAF, USA. J. Radiat. Res. 50: Suppl. A:A21-A28, 2009. [PDF]

Hei T.K., Ballas L.K., Brenner D.J., Geard C.R. Advances in radiobiological studies using a microbeam. J. Radiat. Res. 50 Suppl. A:A7-A12 (2009). [abstract] [PDF]

Bertucci A., Pocock R.D., Randers-Pehrson G., Brenner D.J. Microbeam irradiation of the C. elegans nematode. J. Radiat. Res. 50 Suppl. A:A49-A54 (2009). [abstract] [PDF]

Bigelow A.W., Geard C.R., Randers-Pehrson G., and Brenner D.J. Microbeam-integrated multiphoton imaging system. Rev. Sci. Instrum.79:123707 (2008). [abstract] [PDF]

Brenner DJ. Should computed tomography be the modality of choice for imaging Crohn's disease in children? The radiation risk perspective. Gut 57:1489-1490 (2008). [abstract] [PDF]

Ahuja A.K., Barber R.C., Hardwick R.J., Weil M.M., Genik P.C., Brenner D.J. and Dubrova Y.E. The effects of Atm haploinsufficiency on mutation rate in the mouse germ line and somatic tissue. Mutagenesis 23:367-370 (2008). [abstract] [PDF]

Brenner DJ. The linear-quadratic model is an appropriate methodology for determining isoeffective doses at large doses per fraction. Semin. Radiat. Oncol. 18:234-239 (2008). [abstract] [PDF]

Bigelow A.W., Brenner D.J., Garty G. and Randers-Pehrson G. Single-particle/single-cell ion microbeams as probes of biological mechanisms. IEEE Trans. Plasma Sci. 36:1424-1431 (2008). [abstract] [PDF]

Hei T.K., Zhou H., Ivanov V.N., Hong M., Lieberman H.B., Brenner D.J., Amundson S.A., and Geard C.R. Mechanism of radiation-induced bystander effects: a unifying model. J. Pharm. Pharmacol. 60:943-950 (2008). [abstract] [PDF]

Brenner D.J. Effective dose: a flawed concept that could and should be replaced. Br. J. Radiol. 81:521-523 (2008). [abstract] [PDF]

Brenner D.J. and Huda W. Effective dose: A useful concept in diagnostic radiology? Radiat. Prot. Dosimetry 128:503-508 (2008). [abstract] [PDF]

Hall E.J. and Brenner D. J. Cancer risks from diagnostic radiology. Br. J. Radiol. 81:362-378 (2008). [abstract] [PDF]

Brenner D.J. and Hall E.J. Secondary neutrons in clinical proton radiotherapy: A charged issue. Radiother. Oncol. 86:165-170 (2008). [abstract] [PDF]

Shuryak I., Sachs R.K. and Brenner D.J. Biophysical models of radiation bystander effects: 1. Spatial effects in three-dimensional tissues. Radiat. Res. 168:741-749 (2007) [abstract] [PDF]

Brenner D.J. and Hall E.J. Computed Tomography - An increasing source of radiation exposure. N. Engl. J. Med. 357:2277-2284 [PDF]

Sachs R.K., Shuryak I., Brenner D.J., Fakir H., Hlatky L. and Hahnfeldt P. Second cancers after fractionated radiotherapy: Stochastic population dynamics effects. J. Theoretical Biol. 249:518-531 (2007). [abstract] [PDF]

Hodgson D.C., Koh E-S., Tran T.H., Heydarian M., Tsang R., Pintilie M., Xu T., Huang L., Sachs R.K. and Brenner D.J. Individualized estimates of second cancer risks after contemporary radiation therapy for Hodgkin lymphoma. Cancer 110:2576-2586 (2007). [abstract] [PDF]

Kleinman N.J., David J., Elliston C.D., Hopkins K.M., Smilenov L.B., Brenner D.J., Worgul B.V., Hall E.J. and Lieberman H.B. Mrad9 and atm haploinsufficiency enhance spontaneous and x-ray-induced cataractogenesis in mice. Radiat. Res. 168:567-573 (2007). [abstract] [PDF]

Brenner D.J., Shuryak I., Russo S. and Sachs R.K. Reducing second breast cancers: a potential role for prophylactic mammary irradiation. J. Clin. Oncol. 25:4868-4872 (2007). [abstract] [PDF]

Nikolaev A., Oks E.M., Savkin K., Yushkov G.Yu., Brenner D.J., Johnson G., Randers-Pehrson G., Brown I.G. and MacGill R.A. Surface resistivity tailoring of ceramic insulators for an ion microprobe application. Surface & Coatings Technology 201:8120-8122 (2007). [PDF]

Sedelnikova O.A., Nakamura A., Kovalchuk O., Koturbash I., Mitchell S.A., Marino S.A., Brenner D.J. and Bonner W.M. DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Res. 67:4295-4302 (2007). [abstract] [PDF]

Koh E.S., Tran T.H., Heydarian M., Sachs R.K., Tsang R.W., Brenner D.J., Pintilie M., Xu T., Chung J., Paul N. and Hodgson D.C. A comparison of mantle versus involved-field radiotherapy for Hodgkin's lymphoma: reduction in normal tissue dose and second cancer risk. Radiat. Oncol. 2:13 (2007). [abstract] [PDF]

Brenner D.J. Induced second cancers after prostate-cancer radiotherapy: No cause for concern? Int. J. Radiat. Oncol. Biol. Phys. 65:637-639 (2006). [abstract] [PDF]

Brenner D.J. It is time to retire the computed tomography dose index (CTDI) for CT quality assurance and dose optimization. Med. Phys. 33:1189-1190 (2006). [abstract] [PDF]

Brenner D.J. and Sachs R.K. Estimating radiation-induced cancer risks at very low doses: rationale for using a linear no-threshold approach. Radiat. Environ. Biophys. 44:253-256 (2006). [abstract] [PDF]

Garty G., Ross G.J., Bigelow A.W., Randers-Pehrson G. and Brenner D.J. Testing the stand-alone microbeam at Columbia University. Radiat. Prot. Dosimetry 122:292-296 (2006). [abstract] [PDF]

Hall E.J., Worgul B.V., Smilenov L., Elliston C.D. and Brenner D.J. The relative biological effectiveness of densely ionizing heavy-ion radiation for inducing ocular cataracts in wild type versus mice heterzygous for the ATM gene. Radiat. Environ. Biophys. 45:99-104 (2006). [abstract] [PDF]

Shuryak I., Sachs R.K., Hlatky L., Little M.P., Hahnfeldt P. and Brenner D.J. Radiation-induced leukemia at doses relevant to radiation therapy: Modeling mechanisms and estimating risks. JNCI 98:1974-1806 (2006). [abstract] [PDF]

Ross G.J., Bigelow A.W., Randers-Pehrson G., Peng C.C. and Brenner D.J. Phase-based cell imaging techniques for microbeam irradiations. Nucl. Instrum. Methods Phys. Res. B 241:387-391 (2005). [PDF]

Garty G., Ross G.J., Bigelow A., Randers-Pehrson G. and Brenner D.J. A microbeam irradiator without an accelerator. Nucl. Instrum. Methods Phys. Res. B 241:392-396 (2005). [PDF]

Bigelow A.W., Randers-Pehrson G., Kelly R.P. and Brenner D.J. Laser ion source for Columbia University's microbeam. Nucl. Instrum. Methods Phys. Res. B 241: 874-879 (2005). [PDF]

Garty G., Randers-Pehrson G. and Brenner D.J. Development of a secondary-electron ion-microscope for microbeam diagnostics. Nucl. Instrum. Methods Phys. Res. B 231:60-64 (2005) [PDF]

Bigelow A.W., Ross G.J., Randers-Pehrson G. and Brenner D.J. The Columbia University Microbeam II endstation for cell imaging and irradiation. Nucl. Instrum. Methods Phys. Res. B 231:202-206 (2005) [PDF]

Ross G.J., Garty G., Randers-Pehrson G. and Brenner D.J. A single-particle/single-cell microbeam based on an isotopic alpha source. Nucl. Instrum. Methods Phys. Res. B 231:207-211 (2005) [PDF]

Zhou H., Ivanov V.N., Gillespie J., Geard C.R., Amundson S.A., Brenner D.J., Yu Z., Lieberman H.B. and Hei T.K. Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2  signaling pathway. PNAS 102:14641-14646 (2005) [abstract] [PDF]

Brenner D.J. Letter to the Editor: Is it time to retire the CTDI for CT quality assurance and dose optimization? Med. Phys. 32:3225-3226 (2005). [abstract] [PDF]

Belyakov O.V., Mitchell S.A., Parikh D., Randers-Pehrson G., Marino S.A., Amundson S.A., Geard C.R. and Brenner D.J. Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away. PNAS 102:14203-14208 (2005) [abstract] [PDF]

Sachs R.K. and Brenner D.J. Solid tumor risks after high doses of ionizing radiation. PNAS 102:13040-13045 (2005). [abstract] [PDF]

Brenner D.J. and Georgsson M.A. Mass Screening With CT Colonography: Should the radiation exposure be of concern? Gastroenterology 129:328-337 (2005). [abstract] [PDF]

Hall E.J., Brenner D.J., Worgul B. and Smilenov L. Genetic susceptibility to radiation. Adv. Space Res. 35:249-253 (2005). [abstract] [PDF]

Hande M.P., Azizova T.V., Burak L.E., Khokhryakov V.F., Geard C.R. and Brenner D.J. Complex chromosome aberrations persist in individuals many years after occupational exposure to densely ionizing radiation: An mFISH study. Genes Chromosomes Cancer 44:1-9 (2005). [abstract] [PDF]

Vives S., Loucas B., Vazquez M., Brenner D.J., Sachs R.K., Hlatky L., Cornforth M., Arsuaga J. SCHIP: statistics for chromosome interphase positioning based on interchange data. Bioinformatics 21:3181-3182 (2005). [abstract] [PDF]

Worgul B.V., Smilenov L., Brenner D.J., Vazquez M., Hall E.J. Mice heterozygous for the ATM gene are more sensitive to both X-ray and heavy ion exposure than are wildtypes. Adv. Space Res. 35:254-259 (2005). [abstract] [PDF]

Brenner D.J. and Elliston C.D. In response to Radiation risk of body CT: What to tell our patients and other questions. (R.E. Levatter) Radiology 234:968-970 (2005). [abstract] [PDF]

Brenner D.J. Fractionation and late rectal toxicology. Int. J. Radiat. Oncol. Biol. Phys. 60:1013-1015 (2004). [abstract] [PDF]

Ponnaiya B., Jenkins-Baker G., Brenner D.J., Hall E.J., Randers-Pehrson G. and Geard C.R. Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiat. Res. 162:426-432 (2004). [abstract] [PDF]

Mitchell C.R., Azizova T.V., Hande M.P., Burak L.E., Tsakok J.M., Khokhryakov V.F., Geard C.R. and Brenner D.J. Stable intrachromosomal biomarkers of past exposure to densely ionizing radiation in several chromosomes of exposed individuals. Radiat. Res. 162:257-263 (2004). [abstract] [PDF]

Arsuaga J., Greulich-Bose K.M., Vazquez M., Bruckner M., Hahnfeldt P., Brenner D.J., Sachs R. and Hlatky L. Chromosome spatial clustering inferred from radiogenic aberrations. Int. J. Radiat. Biol. 80:507-515 (2004). [abstract] [PDF]

Brenner D.J. and Elliston C.D. Estimated radiation risks potentially associated with full-body CT screening. Radiology 232:735-738 (2004).  [abstract] [PDF]

Mitchell S.A., Marino S.A., Brenner D.J. and Hall E.J. Bystander effect and adaptive response in C3H 10T½ cells. Int. J. Radiat. Biol. 80:465-472 (2004). [PDF]

Brenner D.J. and Hall E.J. Risk of cancer from diagnostic X-rays. Lancet 363:2192 (2004). [abstract] [PDF]

Brenner D.J. Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer. Radiology 231:440-445 (2004). [abstract] [PDF]

Mitchell S.A., Randers-Pehrson G., Brenner D.J. and Hall E.J. The Bystander Response in C3H 10T(1/2) Cells: The Influence of Cell-to-Cell Contact. Radiat. Res. 161:397-401 (2004). [abstract] [PDF]

Brenner D.J., Doll R., Goodhead D.T., Hall E.J., et al. Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know. Proc. Natl. Acad. Sci. USA 100:13761-13766 (2003). [abstract] [PDF]

Brenner D.J. Hypofractionation for prostate cancer radiotherapy––what are the issues? Int. J. Radiat. Oncol. Biol. Phys. 57:912-914 (2003). [abstract] [PDF]

Zhou H., Randers-Pehrson G., Geard C.R., Brenner D.J., Hall E.J. and Hei T.K. Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells. Radiat. Res. 160:512-516 (2003). [abstract] [PDF]

Hall E.J. and Brenner D.J. The weight of evidence does not support the suggestion that exposure to low doses of X rays increases longevity. Radiology 229:18-19 (2003). [abstract] [PDF]

Fowler J.F., Ritter M.A., Chappell R.J. and Brenner D.J. What hypofractionated protocols should be tested for prostate cancer? Int. J. Radiat. Oncol. Biol. Phys. 56:1093-1104 (2003). [abstract] [PDF]

Brenner D.J. and Sachs R.K. Domestic radon risks may be dominated by bystander effects- But the risks are unlikely to be greater than we thought. Heath Phys 85:103-108 (2003). [abstract] [PDF]

Hande M.P., Azizova T.V., Geard C.R., Burak L.E., Mitchell C.R., Khokhryakov V.F., Vasilenko E.K. and Brenner D.J. Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome. Am. J. Hum. Genet. 72:1162-1170 (2003). [abstract] [PDF]

Brenner D.J. and Hall E.J. Mortality patterns in British and US radiologists: what can we really conclude? BJR 76:1-2 (2003). [abstract] [PDF]

Cornforth M.N., Greulich-Bode K.M., Loucas B.D., Arsuaga J., Vázquez M., Sachs R.K., Brückner M., Molls M., Hahnfeldt P., Hlatky L. and Brenner D.J. Chromosomes are predominantly located randomly with respect to each other in interphase human cells. J. Cell Biol. 159:237-244 (2002). [abstract] [PDF]

Brenner D.J., Sawant S.G., Hande M.P., Miller R.C., Elliston C.D., Fu Z., Randers-Pehrson G. and Marino SA. Routine screening mammography: how important is the radiation-risk side of the benefit-risk equation? Int. J. Radiat. Biol. 78:1065-1067 (2002) [abstract] [PDF]

Brenner D.J. and Hall E.J. Microbeams: a potent mix of physics and biology. Summary of the 5th International Workshop on Microbeam Probes of Cellular Radiation Response. Radiat. Prot. Dosimetry 99:283-286 (2002) [abstract] [PDF]

Worgul B.V., Smilenov L., Brenner D.J., Junk A., Zhou W. and Hall E.J. Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts. Proc. Natl. Acad. Sci. USA 99:9836-9839 (2002). [abstract] [PDF]

Brenner D.J. and Sachs R.K. Do low dose-rate bystander effects influence domestic radon risks? Int. J. Radiat. Biol. 78:593-604 (2002). [abstract] [PDF]

Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D. and Armour E.P. Direct evidence that prostate tumors show high sensitivity to fractionation (low a/b ratio), similar to late-responding normal tissue. Int. J. Radiat. Oncol. Biol. Phys. 52:6-13 (2002). [abstract] [PDF]

Brenner D.J., Martinez A.A., Edmundson G.K., Mitchell C., Thames H.D. and Armour E.P. In response to Dr. Lee. Int. J. Radiat. Oncol. Biol. Phys. 53:1393 [abstract] [PDF]

Brenner D.J. Estimating cancer risks from pediatric CT: Going from the qualitative to the quantitative.. Pediatr. Radiol. 32:228-231 (2002). [abstract] [PDF]

Brenner D.J. and Elliston C.D. The potential impact of bystander effects on radiation risks in a Mars mission. Radiat. Res. 156:612-617 (2001). [abstract] [PDF]

Brenner D.J., Elliston C.D., Hall E.J. and Berdon W.E. Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR 176:289-296 (2001). [abstract] [PDF]

Brenner D.J. and Hall E.J. Dose rate does matter in endovascular brachytherapy. Cardiovasc. Radiat. Med. 2:254-255 (2001). [abstract] [PDF]

Brenner D.J., Little J.B. and Sachs R.K. The bystander effect in radiation oncogenesis II. A quantitative model. Radiat. Res. 155:402-408 (2001). [abstract] [PDF]

Brenner D.J. and Miller R.C. Long-term efficacy of intracoronary irradiation in inhibiting in-stent restenosis. Circulation 103:1330-1332 (2001). [abstract] [PDF]

Brenner D.J., Okladnikova N., Hande P., Burak L., Geard C.R. and Azizova T. Biomarkers specific to densely-ionising (high LET) radiations. Radiat. Prot. Dosimetry 97:69-73 (2001). [abstract] [PDF]

Brenner D.J. and Raabe O.G. Topics Under Debate: Is the Linear-No-Threshold Hypothesis Appropriate for Use in Radiation Protection? Radiat. Prot. Dosim. 97: 279-285 (2001). [abstract] [PDF]

Ponomarev A.L., Cucinotta F.A., Sachs R.K., Brenner D.J. and Peterson L.E. Extrapolation of the DNA fragment-size distribution after high-dose irradiation to predict effects at low doses. Radiat. Res. 156:594-597 (2001). [abstract] [PDF]

Ponomarev A.L., Cucinotta F.A., Sachs R.K. and Brenner D.J. Monte Carlo predictions of DNA fragment-sized distributions for large sizes after HZE particle irradiation. Phys. Med. 17:153-6 Suppl. (2001). [abstract] [PDF]

Randers-Pehrson G., Geard C.R., Johnson G., Elliston C.D. and Brenner D.J. The Columbia University single-ion microbeam. Radiat. Res. 156:210-214 (2001). [abstract] [PDF]

Sawant S.G., Randers-Pehrson G., Geard C.R., Brenner D.J. and Hall E.J. The bystander effect in radiation oncogenesis I. Transformation in C3H 10T1/2 cells in vitro can be initiated in the unirradiated neighbors of irradiated cells. Radiat. Res. 155:397-401 (2001). [abstract] [PDF]

Smilenov L.B., Brenner D.J. and Hall E.J. Modest increased sensitivity to radiation oncogenesis in ATM heterozygous versus wild-type mammalian cells. Cancer Res. 61:5710-5713 (2001). [abstract] [PDF]

Brenner D.J. Rutherford, the Curies, and Radon. Med. Phys. 27:618 (2000). [abstract] [PDF]

Brenner D.J. Towards optimal external-beam fractionation for prostate cancer. Int. J. Radiat. Oncol. Biol. Phys. 48:315-316 (2000). [abstract] [PDF]

Brenner D.J., Curtis R.E., Hall E.J. and Ron E. Second Malignancies in Prostate Cancer Patients After Radiotherapy Compared to Surgery. Cancer 88:398-406 (2000). [abstract] [PDF]

Brenner D.J. and Sachs R.K. Protraction effects in radiation studies: basic biophysics. Radiat. Res. 156:736-737 (2000). [abstract] [PDF]

Brenner D.J., Schiff P.B. and Zablotska L.B. Adjuvant radiotherapy for DCIS. Lancet 355:2071 (2000). [abstract] [PDF]

Dymnikov A.D., Brenner D.J., Johnson G. and Randers-Pehrson G. Theoretical study of short electrostatic lens for the Columbia ion microprobe. Rev. Sci. Instr. 71:1646-1650 (2000). [abstract] [PDF]

Miller R.C., Marino, S.A., Napoli J., Shah H., Hall, E.J., Geard C.R. and Brenner D.J. Oncogenic transformation in C3H10T½ cells by low-energy neutrons. Int. J. Radiat. Biol. 76:327-334 (2000). [abstract] [PDF]

Ponomarev A.L., Brenner D.J., Hlatky L.R., and Sachs R.K. A polymer, random walk model for the size-distribution of large DNA fragments after high linear energy transfer radiation. Radiat. Environ. Biophys. 39:111-120 (2000). [abstract] [PDF]

Brenner D.J. Does fractionation decrease the risk of breast cancer induced by low-LET radiation? Radiat. Res. 151:225-229 (1999). [abstract] [PDF]

Brenner D.J. The relative effectiveness of exposure to 131I at low doses. Health Phys. 76:180-185 (1999). [abstract]

Brenner D.J. and Hall E.J. Fractionation and protraction for radiotherapy of prostate carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 43:1095-1101 (1999). [abstract] [PDF]

Brenner D.J., Leu C-S, Beatty J.F., and Shefer R.E. Clinical relative biological effectiveness of low-energy x-ray emitted by miniature x-ray devices. Phys. Med. Biol. 44:323-333 (1999). [abstract] [PDF]

Brenner D.J. and Sachs R.K. A more robust biologically based ranking criterion for treatment plans. Int. J. Radiat. Oncol. Biol. Phys. 43:697-698 (1999). [abstract] [PDF]

Hall E.J., Miller R.C. and Brenner D.J. Radiobiological principles in intravascular irradiation. Cardiovasc. Radiat. Med. 1:42-47 (1999). [abstract] [PDF]

Johnson K.L., Brenner D.J., Geard C.R., Nath J., and Tucker J.D. Chromosome aberrations of clonal origin in irradiated and unexposed individuals: Assessment and implications. Radiat. Res. 152:1-5 (1999). [abstract] [PDF]

Johnson K.L., Brenner D.J., Nath J., Tucker J.D., and Geard C.R. Radiation-induced breakpoint misrejoining in human chromosomes: Random or non-random? Int. J. Radiat. Biol. 75:131-141 (1999). [abstract] [PDF]

Miller R.C., Marino S.A., Martin S.G., Komatsu K., Geard C.R., Brenner D.J. and Hall E.J. Neutron-energy-dependent cell survival and oncogenic transformation. J. Radiat. Res. 40:53-59 Suppl (1999). [abstract] [PDF]

Miller R.C., Randers-Pehrson G., Geard C.R., Hall E.J., and Brenner D.J. The oncogenic transforming potential of the passage of single alpha particles through mammalian cell nuclei. Proc. Nat. Acad. Sci. USA 96:18-22 (1999). [abstract] [PDF]

Smith L.G., Miller R.C., Richards M., Brenner D.J. and Hall E.J. Investigation of hypersensitivity to fractionated low-dose radiation exposure. Int. J. Radiat. Oncol. Biol. Phys. 45:187-191 (1999). [abstract] [PDF]

Brenner D.J. and Zaider M. Estimating RBEs at clinical doses from microdosimetric spectra. Med Phys. 25:1055-1057 (1998). [abstract] [PDF]

Brenner D.J., Hlatky L.R., Hahnfeldt P.J., Huang Y., and Sachs R.K. The linear-quadratic model and most other common radiobiological models result in similar predictions of time-dose relationships. Radiat. Res. 150:83-91 (1998). [abstract] [PDF]

Brenner D.J., Lubin, J.H. and Ron E. Moving from under the lamppost: can epidemiologists and radiobiologists work together? Nucl Med 37:25-31 (1998). [abstract] [PDF]

Hall E.J., Schiff P.B., Hanks G.E., Brenner D.J., Russo J., Chen J. Sawant S.G., and Pandita T.K. A preliminary report: Frequency of A-T heterozygotes among prostate cancer patients with severe late responses to radiation therapy. Cancer J. Sci. Am. 4:385-389 (1998). [abstract]

Randers-Pehrson G. and Brenner D.J. A practical target system for accelerator-based BNCT which may effectively double the dose rate. Med. Phys. 25:894-6 (1998). [abstract] [PDF]

Sachs R.K., Brenner D.J., Hahnfeldt P.J. and Hlatky L.R. A formalism for analysing large-scale clustering of radiation-induced breaks along chromosomes. Int. J. Radiat. Biol. 74:185-206 (1998). [abstract] [PDF]

Brenner D. J. Radiation biology in brachytherapy. J. Surg. Oncol. 65:66-70 (1997). [abstract] [PDF]

Brenner D.J., Schiff P.B., Huang Y., and Hall E.J. Pulsed dose-rate (PDR) brachytherapy: Design of convenient (daytime only) schedules. Int. J. Radiat. Oncol. Biol. Phys. 39: 809-815 (1997). [abstract] [PDF]

Sachs R.K., Hahnfeld P., and Brenner D.J. Review: The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair. Int. J. Radiat. Biol. 72:351-374 (1997). [abstract] [PDF]

Sachs R.K., Chen A.M., and Brenner D.J. Review: Proximity effects in the production of chromosome aberrations by ionizing radiation. Int. J. Radiat. Biol. 71:1-19 (1997). [abstract] [PDF]

Brenner D.J. Direct biological evidence for a significant neutron dose to survivors of the hiroshima A bomb. Radiat. Res. 145:501-507 (1996). [abstract] [PDF]

Brenner D.J., Hall E.J., Randers-Pehrson G., Huang Y., Johnson G.W., Miller R.W., Wu B., Vazquez M.E., Medvedovsky C. and Worgul B.V. Quantitative comparisons of continuous and pulsed low dose-rate regimens in a model late-effect system. Int. J. Radiat. Oncol. Biol. Phys. 34:905-910 (1996). [abstract] [PDF]

Brenner D.J., Hlatky L.R., Hahnfeldt P.J., Hall E.J., and Sachs R.K. A convenient extension of the linear-quadratic model to include redistribution and reoxygenation. Int. J. Radiat. Oncol. Biol. Phys. 32:379-390 (1995). [abstract] [PDF]

Brenner D.J., Miller R.C., Huang Y. and Hall E.J. The biological effectiveness of radon-progeny aplha particles. III. Quality factors. Radiat. Res. 142:61-69 (1995). [abstract] [PDF]

Brenner D.J. and Sachs R.K. Chromosomal 'fingerprints' of prior exposure to densely-ionizing radiation. Radiat. Res. 140:134-142 (1994). [abstract] [PDF]

Brenner D.J., Hall E.J., Huang Y.P., and Sachs R.K. Optimizing the time course of brachytherapy and other accelerated radiotherapeutic protocols. Int. J. Radiat. Oncol. Biol. Phys. 29:893-901 (1994). [abstract]

Brenner D.J. The significance of dose rate in assessing the hazards of domestic radon exposure. Health Physics 67:76-79 (1994). [abstract]

Hahnfeldt P., Hearst J.E., Brenner D.J., Sachs R.K., and Hlatky L.R. Polymer models for interphase chromosomes. Proc. Nat. Acad. Sci. USA 90:7854-7858 (1993). [abstract] [PDF]